SCHEMBL9489459

SCHEMBL9489459

O=[N+]([O-])c1ccc2ccccc2c1Br

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.60
HPRT1 P00492 1/20 0.56
TSHR P16473 4/20 0.49
TDP1 Q9NUW8 3/20 0.49
CASP6 P55212 1/20 0.47
CTSB P07858 3/20 0.47
POLB P06746 1/20 0.47
CYP3A4 P08684 2/20 0.46
HNF4A P41235 2/20 0.44
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
MAPT P10636 3/20 0.42
KDM4E B2RXH2 2/20 0.42
NCEH1 Q6PIU2 1/20 0.41
CYP2A6 P11509 1/20 0.41
HSD17B10 Q99714 1/20 0.41
CYP1A2 P05177 1/20 0.40
CYP2D6 P10635 1/20 0.40
ALOX15 P16050 1/20 0.40
MAPK1 P28482 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL899430 0.81 ALDH1A1 (0.71) ALDH1A1HPRT1TSHRTDP1CASP6
SCHEMBL23014004 0.79 GRIN2D (0.47) ALDH1A1HPRT1TSHRTDP1CASP6
SCHEMBL187452 0.78 TSHR (0.65) ALDH1A1HPRT1TSHRTDP1CASP6
SCHEMBL1645671 0.78 ALDH1A1 (0.62) ALDH1A1HPRT1TSHRTDP1CASP6
SCHEMBL9488319 0.78 GPR35 (0.50) ALDH1A1HPRT1TSHRTDP1CYP3A4
SCHEMBL3057901 0.77 ALDH1A1 (0.60) ALDH1A1HPRT1TSHRTDP1CASP6
SCHEMBL9187297 0.77 ALDH1A1 (0.60) ALDH1A1HPRT1TSHRTDP1CASP6
SCHEMBL5941163 0.77 ALDH1A1 (0.60) ALDH1A1HPRT1TSHRTDP1CASP6
SCHEMBL1135597 0.77 ALDH1A1 (0.60) ALDH1A1HPRT1TSHRTDP1CASP6
SCHEMBL7985136 0.77 ALDH1A1 (0.60) ALDH1A1HPRT1TSHRTDP1CASP6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114591177-A Synthesis method of 1-bromo-2-nitronaphthalene 苏州锋华新材料科技有限公司 2022-06-07 CN claimed
CN-103555343-B Isothiocyano-containing naphthalene-series liquid crystal monomeric compound and preparation method thereof YANTAI DERUN LIQUID CRYSTAL MATERIALS CO LTD 2015-07-15 CN claimed
CN-103555343-A Isothiocyano-containing naphthalene-series liquid crystal monomeric compound and preparation method thereof YANTAI DERUN LIQUID CRYSTAL MATERIALS CO LTD 2014-02-05 CN claimed
US-20260082804-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2026-03-19 US disclosed
US-20250324904-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2025-10-16 US disclosed
US-12338217-B2 Nitrogen-containing compound, electronic element and electronic device SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2025-06-24 US disclosed
US-20250115554-A1 NITROGEN-CONTAINING COMPOUND, ELECTRONIC ELEMENT AND ELECTRONIC DEVICE SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2025-04-10 US disclosed
US-12187681-B2 Ion channel antagonists/blockers and uses thereof SHANGHAI EAST HOSPITAL (CN) 2025-01-07 US disclosed
US-12108662-B2 Compound for organic electronic element, organic electronic element using same and electronic device therefor DUK SAN NEOLUX CO., LTD. (KR) 2024-10-01 US disclosed
US-20240262838-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND USES THEREOF GUANGZHOU CHINARAY OPTOELECTRONIC MATERIALS LTD. (CN) 2024-08-08 US disclosed
US-12041851-B2 Compound and organic light emitting device comprising same LG CHEM, LTD. (KR) 2024-07-16 US disclosed
WO-2013122364-A2 COMPOUND FOR ORGANIC ELECTRICAL ELEMENT, ORGANIC ELECTRICAL ELEMENT COMPRISING SAME, AND ELECTRONIC DEVICE THEREWITH 덕산하이메탈(주) (KR) 2013-08-22 WO disclosed
WO-2013122364-A2 COMPOUND FOR ORGANIC ELECTRICAL ELEMENT, ORGANIC ELECTRICAL ELEMENT COMPRISING SAME, AND ELECTRONIC DEVICE THEREWITH 덕산하이메탈(주) (KR) 2013-08-22 WO disclosed
WO-2013105747-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME AND ELECTRONIC DEVICE THEREOF 덕산하이메탈(주) (KR) 2013-07-18 WO disclosed
WO-2013081315-A1 COMPOUND FOR ORGANIC ELECTRONIC DEVICE, ORGANIC ELECTRONIC DEVICE COMPRISING SAME AND ELECTRONIC DEVICE COMPRISING THE ORGANIC ELECTRONIC DEVICE 덕산하이메탈(주) (KR) 2013-06-06 WO disclosed
WO-2013081315-A1 COMPOUND FOR ORGANIC ELECTRONIC DEVICE, ORGANIC ELECTRONIC DEVICE COMPRISING SAME AND ELECTRONIC DEVICE COMPRISING THE ORGANIC ELECTRONIC DEVICE 덕산하이메탈(주) (KR) 2013-06-06 WO disclosed
EP-0325892-B1 PROCESS FOR THE PREPARATION OF HALOGENATED PRIMARY AMINES CIBA-GEIGY AG (CH) 1993-02-03 EP disclosed
EP-0473552-A1 Process for the preparation of halogenated aromatic primary amines CIBA-GEIGY AG (CH) 1992-03-04 EP disclosed
US-4960936-A Process for the preparation of halogenated aromatic primary amines CIBA-GEIGY CORPORATION (US) 1990-10-02 US disclosed
EP-0325892-A2 Process for the preparation of halogenated primary amines CIBA-GEIGY AG (CH) 1989-08-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12338217-B2 Nitrogen-containing compound, electronic element and electronic device MNS1, NOS1, NPM1 ALDH1A1 2804/4885HPRT1 1455/4885TSHR 4631/4885
US-20260082804-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LBR, LDLR, LIFR ALDH1A1 2980/4885HPRT1 3366/4885TSHR 157/4885
US-20250115554-A1 NITROGEN-CONTAINING COMPOUND, ELECTRONIC ELEMENT AND ELECTRONIC DEVICE MNS1, NOS1, NPM1 ALDH1A1 2804/4885HPRT1 1455/4885TSHR 4631/4885
US-20240262838-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND USES THEREOF NPR1, NPR3, NUCB2 ALDH1A1 2557/4885HPRT1 391/4885TSHR 3509/4885
US-20250324904-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES MLX, LOXL1, LOXL4 ALDH1A1 2321/4885HPRT1 4159/4885TSHR 1084/4885
US-12108662-B2 Compound for organic electronic element, organic electronic element using same and electronic device therefor OR51E2, WEE2, WEE1 ALDH1A1 725/4885HPRT1 436/4885TSHR 4619/4885
US-12041851-B2 Compound and organic light emitting device comprising same CRY1, CYP1A1, TRPA1 ALDH1A1 25/4885HPRT1 164/4885TSHR 4715/4885
US-12187681-B2 Ion channel antagonists/blockers and uses thereof CACNA1F, CACNA1S, CACNA1D ALDH1A1 1001/4885HPRT1 1050/4885TSHR 2953/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.