Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | CCR1 | P32246 | 2/20 | 0.56 |
| ▸ | CCR5 | P51681 | 2/20 | 0.56 |
| ▸ | CCR8 | P51685 | 2/20 | 0.56 |
| ▸ | METAP1 | P53582 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.56 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 6/20 | 0.48 |
| ▸ | TP53 | P04637 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30338847 | 1.00 | CYP2A6 (0.67) | CYP2A6KDM4ELMNACCR1CCR5 | |
| SCHEMBL24492857 | 0.83 | CYP2A6 (0.58) | CYP2A6KDM4ELMNACCR1CCR5 | |
| SCHEMBL9975012 | 0.83 | CYP2A6 (0.53) | CYP2A6KDM4ELMNACCR1CCR5 | |
| SCHEMBL24493076 | 0.83 | CYP2A6 (0.58) | CYP2A6KDM4ELMNACCR1CCR5 | |
| SCHEMBL22428515 | 0.83 | CYP2A6 (0.58) | CYP2A6KDM4ELMNACCR1CCR5 | |
| SCHEMBL2462770 | 0.82 | CYP2A6 (0.67) | CYP2A6KDM4ELMNACCR1CCR5 | |
| SCHEMBL9974933 | 0.82 | CYP2A6 (0.51) | CYP2A6KDM4ELMNACCR1CCR5 | |
| SCHEMBL12131379 | 0.81 | CCR1 (0.55) | CYP2A6KDM4ELMNACCR1CCR5 | |
| SCHEMBL16383308 | 0.81 | CYP2A6 (0.50) | CYP2A6KDM4ELMNACCR1CCR5 | |
| SCHEMBL24492848 | 0.80 | ATM (0.55) | CYP2A6KDM4ELMNACCR1CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250289818-A1 | HETEROCYCLIC DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND THEIR USE IN THE TREATMENT, AMELIORATION OR PREVENTION OF CANCER | TOLREMO THERAPEUTICS AG (CH) | 2025-09-18 | — | — | US | disclosed |
| CN-116507608-A | Compounds, compositions, and methods | 戴纳立制药公司 | 2023-07-28 | — | — | CN | disclosed |
| US-20230067929-A1 | HETEROCYCLIC DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND THEIR USE IN THE TREATMENT, AMELIORATION OR PREVENTION OF CANCER | TOLREMO THERAPEUTICS AG (CH) | 2023-03-02 | — | — | US | disclosed |
| US-10930853-B2 | Organic light-emitting device | SAMSUNG DISPLAY CO., LTD. (KR) | 2021-02-23 | — | — | US | disclosed |
| WO-2019164778-A1 | PROCESS FOR PREPARING 1-ARYLSULFONYL-PYRROLIDINE-2-CARBOXAMIDE TRANSIENT RECEPTOR POTENTIAL CHANNEL ANTAGONIST COMPOUNDS AND CRYSTALLINE FORMS THEREOF | GENENTECH, INC. (US) | 2019-08-29 | — | — | WO | disclosed |
| EP-3466932-A1 | PRODUCTION METHOD FOR BICYCLIC NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | Kobelco Eco-Solutions Co., Ltd (JP) | 2019-04-10 | — | — | EP | disclosed |
| US-10236454-B2 | Luminescent complexes and display devices | UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) | 2019-03-19 | — | — | US | disclosed |
| US-10186666-B2 | Condensed-cyclic compound and organic light emitting device including the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2019-01-22 | — | — | US | disclosed |
| WO-2019014460-A1 | EAAT2 ENHANCING MOLECULES | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2019-01-17 | — | — | WO | disclosed |
| US-9728805-B2 | Nonaqueous electrolyte and lithium secondary battery using the same | LG CHEM, LTD. (KR) | 2017-08-08 | — | — | US | disclosed |
| EP-2541663-B1 | NONAQUEOUS ELECTROLYTE AND LITHIUM SECONDARY BATTERY USING THE SAME | LG CHEMICAL LTD (KR) | 2017-01-18 | — | — | EP | disclosed |
| US-9120783-B2 | Substituted 3-heteroaroylamino-propionic acid derivatives and their use as pharmaceuticals | SANOFI (FR) | 2015-09-01 | — | — | US | disclosed |
| US-9029559-B2 | Substituted 3-heteroaroylamino-propionic acid derivatives and their use as pharmaceuticals | SANOFI (FR) | 2015-05-12 | — | — | US | disclosed |
| US-20140194445-A1 | SUBSTITUTED 3-HETEROAROYLAMINO-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI (FR) | 2014-07-10 | — | — | US | disclosed |
| US-20140135328-A1 | SUBSTITUTED 3-HETEROAROYLAMINO-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI (FR) | 2014-05-15 | — | — | US | disclosed |
| CN-103328468-A | Alpha-7 nicotinic receptor modulators for the treatment of pain, a psychotic disorder, cognitive impairment or alzheimer's disease | PROXIMAGEN LTD | 2013-09-25 | — | — | CN | disclosed |
| US-20130004859-A1 | NONAQUEOUS ELECTROLYTE AND LITHIUM SECONDARY BATTERY USING THE SAME | LG ENERGY SOLUTION, LTD. (KR) | 2013-01-03 | — | — | US | disclosed |
| US-20130004859-A1 | NONAQUEOUS ELECTROLYTE AND LITHIUM SECONDARY BATTERY USING THE SAME | LG ENERGY SOLUTION, LTD. (KR) | 2013-01-03 | — | — | US | disclosed |
| US-7867980-B2 | Lincosamide derivatives and antimicrobial agents comprising the same as active ingredient | MEIJI SEIKA KAISHA, LTD. (JP) | 2011-01-11 | — | — | US | disclosed |
| US-20100184746-A1 | LINCOSAMIDE DERIVATIVES AND ANTIMICROBIAL AGENTS COMPRISING THE SAME AS ACTIVE INGREDIENT | MEIJI SEIKA KAISHA LTD | 2010-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10236454-B2 | Luminescent complexes and display devices | PAICS, ILK, NOD2 | CYP2A6 4256/4885KDM4E 3060/4885LMNA 2172/4885 |
| US-20140135328-A1 | SUBSTITUTED 3-HETEROAROYLAMINO-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | CTSL, CTSF, CTSV | CYP2A6 363/4885KDM4E 3014/4885LMNA 473/4885 |
| US-20250289818-A1 | HETEROCYCLIC DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND THEIR USE IN THE TREATMENT, AMELIORATION OR PREVENTION OF CANCER | SLC10A1, SLC6A6, SLC10A6 | CYP2A6 249/4885KDM4E 3514/4885LMNA 2303/4885 |
| US-10186666-B2 | Condensed-cyclic compound and organic light emitting device including the same | CRY1, CRY2, CCNE2 | CYP2A6 2249/4885KDM4E 3752/4885LMNA 1208/4885 |
| US-20140194445-A1 | SUBSTITUTED 3-HETEROAROYLAMINO-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | CTSL, CTSF, CTSV | CYP2A6 363/4885KDM4E 3014/4885LMNA 473/4885 |
| US-20230067929-A1 | HETEROCYCLIC DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND THEIR USE IN THE TREATMENT, AMELIORATION OR PREVENTION OF CANCER | SLC10A1, SLC6A6, SLC10A6 | CYP2A6 202/4885KDM4E 3358/4885LMNA 2294/4885 |
| US-20100184746-A1 | LINCOSAMIDE DERIVATIVES AND ANTIMICROBIAL AGENTS COMPRISING THE SAME AS ACTIVE INGREDIENT | SIRT6, LAS1L, MRPS18A | CYP2A6 548/4885KDM4E 701/4885LMNA 99/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.