SCHEMBL10028008

SCHEMBL10028008

COCC(COCC(COCC(COC)OC)OC)OC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKD3 O94806 2/20 0.41
PRKCG P05129 2/20 0.41
PRKCB P05771 2/20 0.41
PRKCA P17252 2/20 0.41
PRKCH P24723 2/20 0.41
PRKCI P41743 2/20 0.41
PRKCE Q02156 2/20 0.41
PRKCQ Q04759 2/20 0.41
PRKCZ Q05513 2/20 0.41
PRKCD Q05655 2/20 0.41
PRKD1 Q15139 2/20 0.41
LPAR1 Q92633 7/20 0.39
LPAR3 Q9UBY5 7/20 0.39
LPAR6 P43657 5/20 0.39
LPAR4 Q99677 5/20 0.39
LPAR5 Q9H1C0 5/20 0.39
LPAR2 Q9HBW0 5/20 0.39
ALDH1A1 P00352 2/20 0.35
AKT1 P31749 1/20 0.32
MAPK1 P28482 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL820179 1.00 PRKD3 (0.41) PRKD3PRKCGPRKCBPRKCAPRKCH
SCHEMBL13225891 1.00 PRKD3 (0.41) PRKD3PRKCGPRKCBPRKCAPRKCH
SCHEMBL51157 0.90
SCHEMBL13166788 0.89 CYP2C9 (0.44) PRKD3PRKCGPRKCBPRKCAPRKCH
SCHEMBL19067466 0.89 CYP2C9 (0.44) PRKD3PRKCGPRKCBPRKCAPRKCH
SCHEMBL19546092 0.89 PRKD3 (0.36) PRKD3PRKCGPRKCBPRKCAPRKCH
SCHEMBL19749216 0.87 LPAR1 (0.42) PRKD3PRKCGPRKCBPRKCAPRKCH
SCHEMBL12355616 0.87 PRKD3 (0.39) PRKD3PRKCGPRKCBPRKCAPRKCH
SCHEMBL14730146 0.87 PRKD3 (0.35) PRKD3PRKCGPRKCBPRKCAPRKCH
SCHEMBL26709585 0.87 LPAR1 (0.42) PRKD3PRKCGPRKCBPRKCAPRKCH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11773277-B2 Use of an ultraviolet radiation absorbing polymer composition (UVRAP) as an UV absorbing agent in a coating for non-living and non-keratinous materials BASF SE 2023-10-03 US disclosed
EP-2906246-B1 VEGF NEUTRALIZING PRODRUGS COMPRISING RANIBIZUMAB FOR THE TREATMENT OF OCULAR CONDITIONS CHARACTERIZED BY OCULAR NEOVASCULARIZATION ASCENDIS PHARMA OPHTHALMOLOGY DIV A/S (DK) 2023-07-26 EP disclosed
US-20180042996-A1 Hydrogel-Linked IL-1ra Prodrug ASCENDIS PHARMA OSTEOARTHRITIS DIVISION A/S (DK) 2018-02-15 US disclosed
US-20170281481-A1 Topical composition comprising plant extracts LINNEA SA (CH) 2017-10-05 US disclosed
US-8741283-B2 Adenosine deaminase anticancer therapy SIGMA-TAU RARE DISEASES, S.A. (PT) 2014-06-03 US disclosed
US-8268318-B2 Polyalkylene oxides having hindered ester-based biodegradable linkers ENZON PHARMACEUTICALS, INC. (US) 2012-09-18 US disclosed
US-8110559-B2 Hindered ester-based biodegradable linkers for oligonucleotide delivery ENZON PHARMACEUTICALS, INC. (US) 2012-02-07 US disclosed
US-8071741-B2 Stable recombinant adenosine deaminase DEFIANTE FARMACEUTICA, S.A. (PT) 2011-12-06 US disclosed
US-20100279408-A1 POLYMERIC SHORT INTERFERING RNA CONJUGATES ENZON PHARMACEUTICALS, INC. (US) 2010-11-04 US disclosed
US-20100234444-A1 HINDERED ESTER-BASED BIODEGRADABLE LINKERS FOR OLIGONUCLEOTIDE DELIVERY ENZON PHARMACEUTICALS, INC. (US) 2010-09-16 US disclosed
US-20090232833-A1 POLYALKYLENE OXIDES HAVING HINDERED ESTER-BASED BIODEGRADABLE LINKERS ENZON PHARMACEUTICALS, INC. (US) 2009-09-17 US disclosed
US-20090202573-A1 POLYMERIC CONJUGATES CONTAINING POSITIVELY-CHARGED MOIETIES ENZON PHARMACEUTICALS, INC. (US) 2009-08-13 US disclosed
US-20090047270-A1 ENZYMATIC ANTICANCER THERAPY ENZON PHARMACEUTICALS, INC. (US) 2009-02-19 US disclosed
US-20090047271-A1 STABLE RECOMBINANT ADENOSINE DEAMINASE ENZON PHARMACEUTICALS, INC. (US) 2009-02-19 US disclosed
US-20090017004-A1 POLYMERIC DRUG DELIVERY SYSTEMS CONTAINING AN AROMATIC ALLYLIC ACID ENZON PHARMACEUTICALS, INC. (US) 2009-01-15 US disclosed
US-20090016985-A1 POLYMERIC DRUG DELIVERY SYSTEM CONTAINING A MULTI-SUBSTITUTED AROMATIC MOIETY ENZON PHARMACEUTICALS, INC. (US) 2009-01-15 US disclosed
US-20080159964-A1 USE OF ADENOSINE DEAMINASE FOR TREATING PULMONARY DISEASE ENZON PHARMACEUTICALS, INC. (US) 2008-07-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100279408-A1 POLYMERIC SHORT INTERFERING RNA CONJUGATES SNRPE, RNASE1, PHAX PRKD3 2283/4885PRKCG 3375/4885PRKCB 3488/4885
US-20090047270-A1 ENZYMATIC ANTICANCER THERAPY RNASE1, ADA, DCTD PRKD3 2630/4885PRKCG 2192/4885PRKCB 1875/4885
US-20080159964-A1 USE OF ADENOSINE DEAMINASE FOR TREATING PULMONARY DISEASE ADA, AMPD2, AMPD1 PRKD3 1038/4885PRKCG 623/4885PRKCB 838/4885
US-20090017004-A1 POLYMERIC DRUG DELIVERY SYSTEMS CONTAINING AN AROMATIC ALLYLIC ACID AADAC, ACSS2, ANXA6 PRKD3 4642/4885PRKCG 4213/4885PRKCB 4440/4885
US-20090202573-A1 POLYMERIC CONJUGATES CONTAINING POSITIVELY-CHARGED MOIETIES PIGO, PHOSPHO1, PAICS PRKD3 3204/4885PRKCG 1971/4885PRKCB 3225/4885
US-20090016985-A1 POLYMERIC DRUG DELIVERY SYSTEM CONTAINING A MULTI-SUBSTITUTED AROMATIC MOIETY ABCB1, PAICS, ABCG2 PRKD3 4671/4885PRKCG 4829/4885PRKCB 4834/4885
US-20090232833-A1 POLYALKYLENE OXIDES HAVING HINDERED ESTER-BASED BIODEGRADABLE LINKERS CES2, PLOD3, FASN PRKD3 4095/4885PRKCG 3061/4885PRKCB 2523/4885
US-20180042996-A1 Hydrogel-Linked IL-1ra Prodrug IL1A, IL1B, IL1R1 PRKD3 2914/4885PRKCG 2097/4885PRKCB 1744/4885
US-20090047271-A1 STABLE RECOMBINANT ADENOSINE DEAMINASE ADA, CDA, DCTD PRKD3 752/4885PRKCG 1493/4885PRKCB 1540/4885
US-20170281481-A1 Topical composition comprising plant extracts CHMP4B, EXOSC9, EXOSC5 PRKD3 2648/4885PRKCG 2080/4885PRKCB 2509/4885
US-20100234444-A1 HINDERED ESTER-BASED BIODEGRADABLE LINKERS FOR OLIGONUCLEOTIDE DELIVERY VEGFA, DCLRE1B, MSN PRKD3 4454/4885PRKCG 4060/4885PRKCB 3895/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.