Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.38 |
| ▸ | NOS1 | P29475 | 2/20 | 0.38 |
| ▸ | NOS2 | P35228 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.32 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.32 |
| ▸ | HRH2 | P25021 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21711088 | 0.82 | CYP2A6 (0.35) | NOS2CYP2A6KDM4EL3MBTL1 | |
| SCHEMBL951059 | 0.79 | NOS3 (0.41) | NOS3NOS1NOS2PARP1DHFR | |
| SCHEMBL1145964 | 0.79 | ALDH1A1 (0.38) | CYP2A6DHFRKDM4EESR1ESR2 | |
| SCHEMBL336161 | 0.79 | SHBG (0.41) | CYP2A6KDM4EESR1ESR2EHMT2 | |
| SCHEMBL19050129 | 0.79 | PRMT5 (0.38) | NOS3NOS1NOS2CYP2A6DHFR | |
| SCHEMBL25759811 | 0.79 | NOS3 (0.36) | NOS3NOS1NOS2PARP1KDM4E | |
| SCHEMBL19791983 | 0.79 | USP7 (0.34) | NOS3NOS1NOS2PARP1DHFR | |
| SCHEMBL9128305 | 0.77 | NOS3 (0.35) | NOS3NOS1NOS2PARP1KDM4E | |
| SCHEMBL2597202 | 0.77 | NOS3 (0.35) | NOS3NOS1NOS2PARP1CHRNB2 | |
| SCHEMBL10268101 | 0.77 | NOS3 (0.56) | NOS3NOS1NOS2PARP1DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3143185-B1 | METHOD FOR THE ELECTROCHEMICAL AMINATION AT BORON DOPED DIAMOND ANODES | COVESTRO DEUTSCHLAND AG (DE) | 2018-10-03 | — | — | EP | claimed |
| EP-3143185-A1 | METHOD FOR PRODUCING 1.5-DIAMINONAPHTHALENE AND 1-AMINO-5-NITRONAPHTHALENE BY DIRECT ELECTROCHEMICAL AMINATION OF NON-ACTIVATED OR DEACTIVATED AROMATIC SYSTEMS ON BORON-DOPED DIAMOND ANODES | Covestro Deutschland AG (DE) | 2017-03-22 | — | — | EP | claimed |
| WO-2015173221-A1 | METHOD FOR PRODUCING 1.5-DIAMINONAPHTHALENE AND 1-AMINO-5-NITRONAPHTHALENE BY DIRECT ELECTROCHEMICAL AMINATION OF NON-ACTIVATED OR DEACTIVATED AROMATIC SYSTEMS ON BORON-DOPED DIAMOND ANODES | COVESTRO DEUTSCHLAND AG (DE) | 2015-11-19 | — | — | WO | claimed |
| WO-2023107597-A2 | BICYCLIC HETEROAROMATIC AMIDE COMPOUNDS AND USES THEREOF | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |
| US-20230128713-A1 | ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND DIAGNOSTIC COMPOSITION INCLUDING THE ORGANOMETALLIC COMPOUND | SAMSUNG ELECTRONICS CO LTD (KR) | 2023-04-27 | — | — | US | disclosed |
| US-20210353602-A1 | COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR | PLEXXIKON INC (US) | 2021-11-18 | — | — | US | disclosed |
| US-20210346358-A1 | COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR | PLEXXIKON INC (US) | 2021-11-11 | — | — | US | disclosed |
| US-20190150445-A1 | SUBSTITUTED HALOGEN(THIO)ACYL COMPOUNDS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-05-23 | — | — | US | disclosed |
| US-20180305830-A1 | METHOD FOR PRODUCING AMINO-FUNCTIONAL AROMATIC COMPOUNDS | COVESTRO DEUTSCHLAND AG (DE) | 2018-10-25 | — | — | US | disclosed |
| EP-3143185-B1 | METHOD FOR THE ELECTROCHEMICAL AMINATION AT BORON DOPED DIAMOND ANODES | COVESTRO DEUTSCHLAND AG (DE) | 2018-10-03 | — | — | EP | disclosed |
| EP-3362588-A1 | METHOD FOR PRODUCING AMINO-FUNCTIONAL AROMATIC COMPOUNDS | Covestro Deutschland AG (DE) | 2018-08-22 | — | — | EP | disclosed |
| EP-2314585-B1 | Condensed benzamide compounds as inhibitors of vanilloid receptor subtype 1 (VR1) activity | JAPAN TOBACCO INC (JP) | 2012-09-12 | — | — | EP | disclosed |
| CN-101542647-B | Magnetorheological formulation | BASF SE | 2012-07-25 | — | — | CN | disclosed |
| US-20120178743-A1 | NOVEL ADENINE COMPOUND AND USE THEREOF | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2012-07-12 | — | — | US | disclosed |
| US-20110263571-A1 | NOVEL AMIDE DERIVATIVE AND USE THEREOF AS MEDICINE | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2011-10-27 | — | — | US | disclosed |
| US-7557213-B2 | Substituted quinolones and methods of use | CHEMOCENTRYX, INC. (US) | 2009-07-07 | — | — | US | disclosed |
| US-7361679-B2 | 2-phenyl-3-heteroarylpropionic acid derivative or salt thereof and medicine containing the same | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2008-04-22 | — | — | US | disclosed |
| US-20070167443-A1 | Substituted quinolones and methods of use | CHEMOCENTRYX, INC. (US) | 2007-07-19 | — | — | US | disclosed |
| CN-1107057-C | 3-amino-1-cyanophenyl-uracils | BAYER AG (DE) | 2003-04-30 | — | — | CN | disclosed |
| CN-1239954-A | 3-amino-1-cyanophenyl-uracils | BAYER AG (DE) | 1999-12-29 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210346358-A1 | COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR | MAP3K20, MAP3K13, MAP3K8 | NOS3 3992/4885NOS1 3616/4885NOS2 3812/4885 |
| US-20070167443-A1 | Substituted quinolones and methods of use | TOP2A, NQO2, TOP2B | NOS3 3855/4885NOS1 4414/4885NOS2 3745/4885 |
| US-20210353602-A1 | COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR | MAP3K20, MAP3K13, MAP3K8 | NOS3 3992/4885NOS1 3616/4885NOS2 3812/4885 |
| US-20230128713-A1 | ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND DIAGNOSTIC COMPOSITION INCLUDING THE ORGANOMETALLIC COMPOUND | ORC3, LEF1, OCIAD1 | NOS3 2270/4885NOS1 862/4885NOS2 2140/4885 |
| US-20110263571-A1 | NOVEL AMIDE DERIVATIVE AND USE THEREOF AS MEDICINE | MMP9, MMP10, MMP2 | NOS3 125/4885NOS1 153/4885NOS2 107/4885 |
| US-20180305830-A1 | METHOD FOR PRODUCING AMINO-FUNCTIONAL AROMATIC COMPOUNDS | DDC, BTD, BCAT1 | NOS3 653/4885NOS1 955/4885NOS2 582/4885 |
| US-20190150445-A1 | SUBSTITUTED HALOGEN(THIO)ACYL COMPOUNDS | ACOT7, AGPAT5, TST | NOS3 4610/4885NOS1 4735/4885NOS2 4706/4885 |
| US-20120178743-A1 | NOVEL ADENINE COMPOUND AND USE THEREOF | ADORA1, HRH4, P2RY10 | NOS3 1042/4885NOS1 452/4885NOS2 681/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.