SCHEMBL1133469

SCHEMBL1133469

CC(C)C1CCC(C)(OC(O)C(C)O)CC1

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30277969 0.84 L3MBTL1 (0.32) L3MBTL1
SCHEMBL3850142 0.77
SCHEMBL1133727 0.77
SCHEMBL6562843 0.76
SCHEMBL3630558 0.75
SCHEMBL5014867 0.75
SCHEMBL30659514 0.74 TRPA1 (0.33)
SCHEMBL28005980 0.73
SCHEMBL612218 0.73
SCHEMBL2480864 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 524 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10392371-B2 Compounds useful as modulators of TRPM8 SENOMYX, INC. (US) 2019-08-27 US claimed
US-20190099342-A1 COOLING PRODUCT SYMRISE AG (DE) 2019-04-04 US claimed
EP-2932858-A1 Homovanillic acid esters, in particular for achieving an impression of heat and/or spiciness Symrise AG (DE) 2015-10-21 EP claimed
EP-4103144-B1 COMPOSITIONS COMPRISING UV-FILTERS AND ONE OR MORE (BIO)-ALKANEDIOLS SYMRISE AG (DE) 2026-05-27 EP disclosed
EP-4110277-B1 COMPOSITIONS COMPRISING (BIO)-ALKANEDIOLS SYMRISE AG (DE) 2026-04-22 EP disclosed
EP-4725476-A2 COMPOSITIONS FOR REDUCING SALTY TASTE AND USES THEREOF Firmenich SA (CH) 2026-04-15 EP disclosed
EP-3045161-B1 Use of active mixtures of 1,2-hexanediol and 1,2-octanediol in cosmetic, pharmaceutical or dermatological emulsions SYMRISE AG (DE) 2026-03-25 EP disclosed
EP-4025675-B1 A PERFUME OIL MIXTURE SYMRISE AG (DE) 2026-03-18 EP disclosed
EP-4706780-A2 COMPOSITIONS COMPRISING UV-FILTERS AND ONE OR MORE (BIO)-ALKANEDIOLS Symrise AG (DE) 2026-03-11 EP disclosed
US-20260041094-A1 Compositions Comprising an Antimicrobial Boosting Agent SYMRISE AG (DE) 2026-02-12 US disclosed
US-20260034042-A1 Composition with Improved SPF and UVA Photoprotection SYMRISE AG (DE) 2026-02-05 US disclosed
US-20110034486-A1 USE OF PTEROCARPANS AS ACTIVE ANTI-CELLULITE INGREDIENTS SYMRISE GMBH & CO., KG (DE) 2011-02-10 US disclosed
WO-2010149798-A2 USE OF POLYOLS FOR ENHANCING THE COOLING EFFECT OF A COOLING SUBSTANCE AND COOLING MIXTURES HAVING AN ENHANCED COOLING EFFECT SYMRISE AG (DE) 2010-12-29 WO disclosed
EP-2186506-A1 Teeth cleaning compound containing menthol with reduced bitter sensation Symrise GmbH & Co. KG (DE) 2010-05-19 EP disclosed
EP-2033688-A2 Oxalic acid derivatives and their use as physiological cooling agents Symrise GmbH & Co. KG (DE) 2009-03-11 EP disclosed
EP-1958627-A2 Use of certain menthyl-3-oxocarbonic acid esters as physiological cooling agents Symrise GmbH & Co. KG (DE) 2008-08-20 EP disclosed
US-20080175800-A1 USE OF SPECIFIC MENTHYL 3-OXOCARBOXYLIC ACID ESTERS AS PHYSIOLOGICALLY ACTIVE COOLING SUBSTANCES SYMRISE GMBH & CO. KG (DE) 2008-07-24 US disclosed
US-20080096969-A1 N alpha-(Menthanecarbonyl)amino acid amides and use thereof as physiological cooling active ingredients SYMRISE GMBH & CO. KG (DE) 2008-04-24 US disclosed
EP-1913976-A1 N-alpha-(menthane carbonyl) amino acid amides and their use as physiological coolants Symrise GmbH & Co. KG (DE) 2008-04-23 EP disclosed
US-20070202188-A1 Use of alkene carboxlic acid n alkylamides as flavouring agents SYMRISE GMBH & CO. KG (DE) 2007-08-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190099342-A1 COOLING PRODUCT TRPA1, TRPV2, NISCH L3MBTL1 4627/4885
US-20260041094-A1 Compositions Comprising an Antimicrobial Boosting Agent TLR7, MYC, ERG28 L3MBTL1 3482/4885
US-10392371-B2 Compounds useful as modulators of TRPM8 TRPM8, TRPM4, TRPM6 L3MBTL1 3284/4885
US-20110034486-A1 USE OF PTEROCARPANS AS ACTIVE ANTI-CELLULITE INGREDIENTS FABP4, PLIN1, CPT1B L3MBTL1 2047/4885
US-20070202188-A1 Use of alkene carboxlic acid n alkylamides as flavouring agents TAS2R41, TAS2R1, TAS2R14 L3MBTL1 3554/4885
US-20080096969-A1 N alpha-(Menthanecarbonyl)amino acid amides and use thereof as physiological cooling active ingredients NMBR, RIMKLA, NAAA L3MBTL1 4785/4885
US-20080175800-A1 USE OF SPECIFIC MENTHYL 3-OXOCARBOXYLIC ACID ESTERS AS PHYSIOLOGICALLY ACTIVE COOLING SUBSTANCES ECI1, OTC, MDH2 L3MBTL1 1993/4885
US-20260034042-A1 Composition with Improved SPF and UVA Photoprotection TYR, ERG28, CUTA L3MBTL1 4497/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.