SCHEMBL114253

SCHEMBL114253

CC(=O)c1oc(C)c2ccccc12

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.47
CA12 O43570 2/20 0.43
CA9 Q16790 2/20 0.43
CYP2C19 P33261 6/20 0.41
EYA3 Q99504 2/20 0.41
MAPT P10636 2/20 0.41
HTT P42858 2/20 0.41
MITF O75030 1/20 0.41
LMNA P02545 1/20 0.41
TP53 P04637 1/20 0.40
HSD17B10 Q99714 1/20 0.40
KDM4E B2RXH2 3/20 0.39
CYP2C9 P11712 1/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
HPGD P15428 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
KMT2A Q03164 1/20 0.37
MCL1 Q07820 1/20 0.37
ALDH1A1 P00352 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7861729 0.83 MCL1 (0.49) CYP2C19EYA3MAPTHTTKDM4E
SCHEMBL26637997 0.82 FLT3 (0.51) GAACA12CA9MAPTLMNA
SCHEMBL2790486 0.82 KDM4E (0.41) GAACYP2C19EYA3MAPTTP53
SCHEMBL9399721 0.79 SMN1; SMN2 (0.38) GAACYP2C19EYA3MAPTLMNA
SCHEMBL27917704 0.79 KDM4E (0.40) GAACYP2C19EYA3MAPTHTT
SCHEMBL25419958 0.76 HPGD (0.48) GAACYP2C19MAPTLMNATP53
SCHEMBL2607276 0.74 CYP1A2 (0.47) CYP2C19EYA3MAPTLMNAHSD17B10
SCHEMBL114250 0.72 KMT2A (0.60) HTTLMNATP53HSD17B10KDM4E
SCHEMBL9657351 0.72 CYP2C19 (0.63) GAACA12CA9CYP2C19EYA3
SCHEMBL181822 0.69 THRB (0.52) GAACA12CA9MAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 397 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018145219-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING ADDICTIONS BY MEANS OF AVERSIVE COUNTERCONDITIONING SERANI MOSTAZAL JORGE (CL) 2018-08-16 WO claimed
EP-1385470-B1 FRAGRANT MIXTURES WITH INCREASED STRENGTH OF ODOR SYMRISE GMBH & CO KG (DE) 2007-08-08 EP claimed
US-12630783-B2 Muguet type fragrance compounds SYMRISE AG (DE) 2026-05-19 US disclosed
US-12630781-B2 Fragrance or flavour mixture SYMRISE AG (DE) 2026-05-19 US disclosed
US-12625123-B2 Device and method for the analytical and sensory determination of the release of an active substance from a release system SYMRISE AG (DE) 2026-05-12 US disclosed
EP-4731617-A1 USE OF DIHYDROPYRAN DERIVATIVES AS AROMA CHEMICALS BASF SE (DE) 2026-04-29 EP disclosed
EP-4728447-A1 ENVIRONMENTAL ATTRIBUTES FOR AROMA CHEMICAL BASF SE (DE) 2026-04-22 EP disclosed
EP-4077299-B1 SUBSTITUTED 4-METHYLENE-TETRAHYDROPYRANS, 4-METHYL-DIHYDROPYRANS AND 4-METHYL-TETRAHYDROPYRANS AND USE THEREOF AS AROMA CHEMICALS BASF SE (DE) 2026-04-01 EP disclosed
US-12590265-B2 1-norbornan-2-ylpropan-2-one as a fragrance SYMRISE AG (DE) 2026-03-31 US disclosed
US-12583833-B2 Enrichment of a diastereomer in Magnolan SYMRISE AG (DE) 2026-03-24 US disclosed
US-12577495-B2 Fragrance mixtures containing 1-(4,4-dimethylcyclohexen-1-yl) ethanon SYMRISE AG (DE) 2026-03-17 US disclosed
US-20070254826-A1 Novel uses of 4-methyl-5-hydroxy-hexanoic acid lactone SYMRISE GMBH & CO. KG (DE) 2007-11-01 US disclosed
EP-1385470-B1 FRAGRANT MIXTURES WITH INCREASED STRENGTH OF ODOR SYMRISE GMBH & CO KG (DE) 2007-08-08 EP disclosed
US-20070072789-A1 2-Methyl-5-phenylpentanal used as a rose odoriferous substance SYMRISE GMBH & CO. KG (DE) 2007-03-29 US disclosed
US-20070037733-A1 Use of 3-cyclohexenyl-1-propanol as a fragrance SYMRISE GMBH & CO. KG (DE) 2007-02-15 US disclosed
US-20070020210-A1 Methods of reducing the perception of body odors with olfactory adaptation and cross-adapting agents MONELL CHEMICAL SENSES CENTER 2007-01-25 US disclosed
US-20060211597-A1 Cis-3,3,5-trimethylcyclohexyl esters SYMRISE AG (DE) 2006-09-21 US disclosed
US-20060166857-A1 4,8-Dimethyl-7-nonen-2-one and 4,8-dimethylnonan-2-one used as perfumes SYMRISE GMBH & CO. KG (DE) 2006-07-27 US disclosed
US-20060135400-A1 4-Cyclohexyl-2-butanol as an odiferous substance SYMRISE GMBH & CO. KG (DE) 2006-06-22 US disclosed
US-20020192174-A1 Perfume mixtures with increased odor intensity SYMRISE GMBH & CO. KG (DE) 2002-12-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12583833-B2 Enrichment of a diastereomer in Magnolan TRPA1, ENO1, ADH1A GAA 4499/4885CA12 199/4885CA9 292/4885
US-12577495-B2 Fragrance mixtures containing 1-(4,4-dimethylcyclohexen-1-yl) ethanon ALG3, FAAH, FAAH2 GAA 3796/4885CA12 2480/4885CA9 2509/4885
US-12630783-B2 Muguet type fragrance compounds MGAT1, RFT1, CPT1A GAA 4754/4885CA12 3951/4885CA9 4250/4885
US-12625123-B2 Device and method for the analytical and sensory determination of the release of an active substance from a release system TAS2R7, TAS2R42, TAS2R39 GAA 593/4885CA12 276/4885CA9 374/4885
US-12590265-B2 1-norbornan-2-ylpropan-2-one as a fragrance OR10J3, TAS2R40, TAS2R50 GAA 1921/4885CA12 2947/4885CA9 3370/4885
US-12630781-B2 Fragrance or flavour mixture NOTUM, FFAR2, FFAR1 GAA 3192/4885CA12 1246/4885CA9 2845/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.