Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9600152 | 0.81 | KMT2A (0.50) | L3MBTL1KMT2APRMT1TDP1LMNA | |
| SCHEMBL10875431 | 0.81 | ALDH1A1 (0.55) | L3MBTL1KMT2APRMT1TDP1LMNA | |
| SCHEMBL5516006 | 0.79 | KMT2A (0.49) | L3MBTL1KMT2APRMT1TDP1LMNA | |
| SCHEMBL29596510 | 0.78 | HRH1 (0.50) | L3MBTL1KMT2APRMT1TDP1LMNA | |
| SCHEMBL1272069 | 0.78 | KMT2A (0.47) | L3MBTL1KMT2APRMT1TDP1LMNA | |
| SCHEMBL1272072 | 0.78 | LMNA (0.54) | L3MBTL1KMT2APRMT1TDP1LMNA | |
| SCHEMBL51377 | 0.78 | HRH1 (0.50) | L3MBTL1KMT2APRMT1TDP1LMNA | |
| SCHEMBL1457801 | 0.78 | L3MBTL1 (0.47) | L3MBTL1KMT2APRMT1TDP1LMNA | |
| SCHEMBL496697 | 0.78 | TDP1 (0.54) | L3MBTL1KMT2ATDP1LMNAHRH1 | |
| Potassium Ion SCHEMBL9065490 | 0.77 | ALDH1A1 (0.55) | L3MBTL1KMT2APRMT1TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4150232-A | NICKEL ELECTROPLATING BATH BRIGHTENER ADDITIVES | CILAG-CHEMIE A.G. (CH) | 1979-04-17 | — | — | US | disclosed |
| US-4148797-A | LEVELING AND BRIGHTENING AGENT FOR NICKEL ELECTROPLATING BATHS | CILAG-CHEMIE A.G. (CH) | 1979-04-10 | — | — | US | disclosed |
| US-4120859-A | (N-Substituted-pyridyl)-alkyl sulfonic acid betaines as electroplating additives | CILAG-CHEMIE A.G. (CH) | 1978-10-17 | — | — | US | disclosed |
| US-4067785-A | PYRIDYL ALKYL SULFONIC ACID BETAINES | CILAG-CHEMIE A.G. (CH) | 1978-01-10 | — | — | US | disclosed |