Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.62 |
| ▸ | CA1 known ✓ | P00915 | 2/20 | 0.59 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.52 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.50 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.50 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.49 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.49 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.48 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.47 |
| ▸ | LAP3 | P28838 | 1/20 | 0.47 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28842326 | 1.00 | CA2 (0.62) | CA2CA1GPR84GRIK1GRIK2 | |
| SCHEMBL28842327 | 1.00 | CA2 (0.62) | CA2CA1GPR84GRIK1GRIK2 | |
| SCHEMBL9950870 | 1.00 | CA2 (0.62) | CA2CA1GPR84GRIK1GRIK2 | |
| SCHEMBL1357451 | 1.00 | CA2 (0.62) | CA2CA1GPR84GRIK1GRIK2 | |
| SCHEMBL28842314 | 1.00 | CA2 (0.62) | CA2CA1GPR84GRIK1GRIK2 | |
| SCHEMBL28842452 | 1.00 | CA2 (0.62) | CA2CA1GPR84GRIK1GRIK2 | |
| SCHEMBL34463224 | 0.96 | CA2 (0.57) | CA2CA1GPR84GRIK1GRIK2 | |
| Norleucine SCHEMBL28842453 | 0.91 | CA2 (0.57) | CA2CA1GPR84GRIK1GRIK2 | |
| Norleucine SCHEMBL30646313 | 0.91 | CA2 (0.57) | CA2CA1GPR84GRIK1GRIK2 | |
| SCHEMBL29213762 | 0.89 | FABP3 (0.54) | CA2CA1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1892 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250025380-A1 | PERSONAL CARE DISSOLVABLE SHEET, COMPOSITIONS, METHODS OF MAKING AND USING THE SAME | IPX, LLC (US) | 2025-01-23 | — | — | US | claimed |
| EP-1799308-B1 | CONDITIONING SHAMPOOS WITH DETERGENT SOLUBLE SILICONES | COLGATE PALMOLIVE CO (US) | 2014-06-04 | — | — | EP | claimed |
| US-8535651-B2 | Water soluble polymer complexes with surfactants | WSP CHEMICALS & TECHNOLOGY, LLC (US) | 2013-09-17 | — | — | US | claimed |
| US-20120251475-A1 | WATER SOLUBLE POLYMER COMPLEXES WITH SURFACTANTS | WSP CHEMICALS & TECHNOLOGY, LLC (US) | 2012-10-04 | — | — | US | claimed |
| US-7754794-B2 | Methods of treating keratin based substrates | WSP CHEMICAL & TECHNOLOGY, LLC (US) | 2010-07-13 | — | — | US | claimed |
| US-7405188-B2 | Polymeric gel system and compositions for treating keratin substrates containing same | WSP CHEMICALS & TECHNOLOGY, LLC (US) | 2008-07-29 | — | — | US | claimed |
| EP-1799308-A1 | CONDITIONING SHAMPOOS WITH DETERGENT SOLUBLE SILICONES | Colgate-Palmolive Company (US) | 2007-06-27 | — | — | EP | claimed |
| WO-2006044296-A1 | CONDITIONING SHAMPOOS WITH DETERGENT SOLUBLE SILICONES | COLGATE-PALMOLIVE COMPANY (US) | 2006-04-27 | — | — | WO | claimed |
| US-20060079415-A1 | Conditioning shampoos with detergent soluble silicones | COLGATE-PALMOLIVE COMPANY | 2006-04-13 | — | — | US | claimed |
| US-20050276778-A1 | Water soluble polymer complexes with surfactants | WSP CHEMICALS & TECHNOLOGY, LLC (US) | 2005-12-15 | — | — | US | claimed |
| WO-2005099654-A1 | WATER SOLUBLE POLYMER COMPLEXES WITH SURFACTANTS | WSP CHEMICALS & TECHNOLOGY, LLC (US) | 2005-10-27 | — | — | WO | claimed |
| US-6939536-B2 | Cosmetic compositions containing water-soluble polymer complexes | WSP CHEMICALS & TECHNOLOGY, LLC (US) | 2005-09-06 | — | — | US | claimed |
| US-20050074417-A1 | Polymeric gel system and compositions for treating keratin substrates containing same | WSP CHEMICALS & TECHNOLOGY, LLC (US) | 2005-04-07 | — | — | US | claimed |
| US-20030064044-A1 | Cosmetic compositions containing water-soluble polymer complexes | CHEMLOGICS GROUP, LLC | 2003-04-03 | — | — | US | claimed |
| WO-2002083073-A2 | COSMETIC COMPOSITIONS CONTAINING WATER-SOLUBLE POLYMER COMPLEXES | WSP CHEMICAL & TECHNOLOGY LLC (US) | 2002-10-24 | — | — | WO | claimed |
| EP-1046390-A1 | Compositions and methods for cleaning and removing contaminants from hair | Calgon Corporation (US) | 2000-10-25 | — | — | EP | claimed |
| EP-4103335-B1 | BOTTLE ADAPTED FOR STORING A LIQUID COMPOSITION WITH AN AESTHETIC DESIGN SUSPENDED THEREIN | PROCTER & GAMBLE (US) | 2026-05-20 | — | — | EP | disclosed |
| EP-3894015-B1 | SHAMPOO COMPOSITION COMPRISING SHEET-LIKE MICROCAPSULES | PROCTER & GAMBLE (US) | 2026-05-20 | — | — | EP | disclosed |
| WO-1983003608-A1 | TETRA-SUBSTITUTED AMMONIUM SALT OF N-PHOSPHONOMETHYLGLYCINE AND THEIR USES AS HERBICIDES AND PLANT GROWTH REGULANTS | STAUFFER CHEMICAL CO (US) | 1983-10-27 | — | — | WO | disclosed |
| US-4120688-A | AMINOMETHYLPHOSPHONIC ACID | THE PROCTOR & GAMBLE COMPANY (US) | 1978-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060079415-A1 | Conditioning shampoos with detergent soluble silicones | SMURF1, SGMS1, SGMS2 | CA2 4542/4885CA1 4198/4885GPR84 797/4885 |
| US-20050074417-A1 | Polymeric gel system and compositions for treating keratin substrates containing same | KRT18, CUTA, S100A10 | CA2 296/4885CA1 492/4885GPR84 917/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.