Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | KDM6B | O15054 | 1/20 | 0.32 |
| ▸ | KDM5C | P41229 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.32 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17853277 | 0.97 | ALDH1A1 (0.53) | ALDH1A1LMNASLC15A2TDP1ACHE | |
| SCHEMBL17853276 | 0.97 | ALDH1A1 (0.53) | ALDH1A1LMNASLC15A2TDP1ACHE | |
| SCHEMBL17776318 | 0.97 | ALDH1A1 (0.53) | ALDH1A1LMNASLC15A2TDP1ACHE | |
| SCHEMBL10086608 | 0.97 | ALDH1A1 (0.53) | ALDH1A1LMNASLC15A2TDP1ACHE | |
| SCHEMBL18769029 | 0.97 | ALDH1A1 (0.53) | ALDH1A1LMNASLC15A2TDP1ACHE | |
| SCHEMBL18768950 | 0.97 | ALDH1A1 (0.53) | ALDH1A1LMNASLC15A2TDP1ACHE | |
| SCHEMBL17853275 | 0.97 | ALDH1A1 (0.53) | ALDH1A1LMNASLC15A2TDP1ACHE | |
| SCHEMBL22198371 | 0.97 | ALDH1A1 (0.53) | ALDH1A1LMNASLC15A2TDP1ACHE | |
| SCHEMBL22198424 | 0.97 | ALDH1A1 (0.53) | ALDH1A1LMNASLC15A2TDP1ACHE | |
| SCHEMBL17971011 | 0.97 | ALDH1A1 (0.53) | ALDH1A1LMNASLC15A2TDP1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118019889-A | Method for producing chemi-thermo-mechanical fibre pulp from non-woody plant material, and an automated line for producing said pulp by said method | 瑞利夫业法国有限公司 | 2024-05-10 | — | — | CN | disclosed |
| US-20230346948-A1 | Lipid conjugated peptide inhibitors of PICK1 | UNIVERSITY OF COPENHAGEN (DK) | 2023-11-02 | — | — | US | disclosed |
| US-20230285576-A1 | TREATMENT OF CANCER USING A CYCLODEXTRIN-CONTAINING POLYMER-TOPOISOMERASE INHIBITOR CONJUGATE AND A PARP INHIBITOR | ELLIPSES PHARMA LTD (GB) | 2023-09-14 | — | — | US | disclosed |
| CN-111606806-A | Degradable photoresist resin monomer synthesized from dimethyl bicyclo [3.3.1] nonane diketone and synthesis method thereof | 徐州博康信息化学品有限公司 | 2020-09-01 | — | — | CN | disclosed |
| EP-3100728-B1 | PHARMACEUTICAL COMPOSITIONS COMPRISING PRASUGREL AND CYCLODEXTRIN DERIVATIVES AND METHODS OF MAKING AND USING THE SAME | CYDEX PHARMACEUTICALS INC (US) | 2019-11-20 | — | — | EP | disclosed |
| WO-2019078522-A1 | CEREBLON PROTEIN DEGRADATION INDUCING COMPOUND, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER, CONTAINING SAME AS ACTIVE INGREDIENT | 한국화학연구원 | 2019-04-25 | — | — | WO | disclosed |
| US-10111863-B2 | Pharmaceutical compositions comprising prasugrel and cyclodextrin derivatives and methods of making and using the same | CYDEX PHARMACEUTICALS, INC. (US) | 2018-10-30 | — | — | US | disclosed |
| US-20170355743-A1 | INSULIN RECEPTOR PARTIAL AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2017-12-14 | — | — | US | disclosed |
| WO-2017205964-A1 | AMINOSTEROID DERIVATIVES AND PROCESS FOR PRODUCING SAME | UNIVERSITé LAVAL (CA) | 2017-12-07 | — | — | WO | disclosed |
| US-20170274091-A1 | BENZODIAZEPINES AND CONJUGATES THEREOF | IMMUNOGEN, INC. | 2017-09-28 | — | — | US | disclosed |
| US-20110160159-A1 | TREATMENT OF CANCER | CERULEAN PHARMA INC. | 2011-06-30 | — | — | US | disclosed |
| US-7968545-B2 | Compositions useful as inhibitors of voltage-gated ion channels | VERTEX PHARMACEUTICALS INC. (US) | 2011-06-28 | — | — | US | disclosed |
| US-20110152512-A1 | CYCLODEXTRIN-BASED POLYMERS FOR THERAPEUTICS DELIVERY | CERULEAN PHARMA INC. | 2011-06-23 | — | — | US | disclosed |
| WO-2010132711-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING PRASUGREL AND CYCLODEXTRIN DERIVATIVES AND METHODS OF MAKING AND USING THE SAME | CYDEX PHARMACEUTICALS, INC. (US) | 2010-11-18 | — | — | WO | disclosed |
| US-20100291056-A1 | Pharmaceutical Compositions Comprising Prasugrel and Cyclodextrin Derivatives and Methods of Making and Using the Same | CITIBANK, N.A., AS ADMINISTRATIVE AGENT | 2010-11-18 | — | — | US | disclosed |
| US-20100273193-A1 | Triacetone Triperoxide and Diacetone Diperoxide Derivatives, Method for the Preparation and Use Thereof | BAM Bundesanstalt fur Materialforschung und-pruefung (DE) | 2010-10-28 | — | — | US | disclosed |
| US-4524207-A | Process for preparing substituted 1,3-dihydrospiro[benzo(c)thiophene]s | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1985-06-18 | — | — | US | disclosed |
| US-4409229-A | Antidepressive and tranquilizing substituted 1,3-dihydrospiro[benzo(c)thiophene]s | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1983-10-11 | — | — | US | disclosed |
| EP-0030092-A1 | Guanidine derivatives, processes for their manufacture and pharmaceutical compositions containing them | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1981-06-10 | — | — | EP | disclosed |
| US-4021546-A | Pro-drug forms of digoxin and method of preparing and using same | INTERX RESEARCH CORPORATION (US) | 1977-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230285576-A1 | TREATMENT OF CANCER USING A CYCLODEXTRIN-CONTAINING POLYMER-TOPOISOMERASE INHIBITOR CONJUGATE AND A PARP INHIBITOR | PARP1, TOP1, PARP2 | ALDH1A1 536/4885LMNA 1474/4885SLC15A2 3876/4885 |
| US-10111863-B2 | Pharmaceutical compositions comprising prasugrel and cyclodextrin derivatives and methods of making and using the same | P2RY6, GP6, PFKP | ALDH1A1 2763/4885LMNA 3458/4885SLC15A2 2627/4885 |
| US-20230346948-A1 | Lipid conjugated peptide inhibitors of PICK1 | PEBP1, DAB2IP, PDCD6IP | ALDH1A1 4699/4885LMNA 4373/4885SLC15A2 4234/4885 |
| US-20170274091-A1 | BENZODIAZEPINES AND CONJUGATES THEREOF | GABBR1, GABRA1, GABBR2 | ALDH1A1 246/4885LMNA 1844/4885SLC15A2 1379/4885 |
| US-20100291056-A1 | Pharmaceutical Compositions Comprising Prasugrel and Cyclodextrin Derivatives and Methods of Making and Using the Same | P2RY6, GP6, PFKP | ALDH1A1 2763/4885LMNA 3458/4885SLC15A2 2627/4885 |
| US-20100273193-A1 | Triacetone Triperoxide and Diacetone Diperoxide Derivatives, Method for the Preparation and Use Thereof | NASP, HSD17B1, PM20D2 | ALDH1A1 145/4885LMNA 3250/4885SLC15A2 1997/4885 |
| US-20170355743-A1 | INSULIN RECEPTOR PARTIAL AGONISTS | INSR, GPR119, IRS1 | ALDH1A1 4716/4885LMNA 4484/4885SLC15A2 2837/4885 |
| US-20110160159-A1 | TREATMENT OF CANCER | TOP1, TOP2A, TOP2B | ALDH1A1 1266/4885LMNA 1598/4885SLC15A2 3450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.