SCHEMBL147844

SCHEMBL147844

CCCOC(=O)c1ccc(N(C)C)cc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.66
TSHR P16473 5/20 0.66
ESR1 P03372 2/20 0.66
CHRM1 P11229 1/20 0.66
SLC6A2 P23975 1/20 0.66
KDR P35968 1/20 0.66
TDP1 Q9NUW8 1/20 0.66
LMNA P02545 4/20 0.62
HPGD P15428 5/20 0.59
MAPT P10636 5/20 0.59
HSD17B10 Q99714 3/20 0.58
CYP3A4 P08684 2/20 0.58
KDM4E B2RXH2 4/20 0.58
NPC1 O15118 3/20 0.58
SMN1; SMN2 Q16637 3/20 0.58
RAB9A P51151 3/20 0.58
MAPK1 P28482 2/20 0.58
GAA P10253 1/20 0.58
L3MBTL1 Q9Y468 1/20 0.55
STS P08842 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1506126 0.91 ALDH1A1 (0.65) ALDH1A1TSHRESR1CHRM1SLC6A2
SCHEMBL357704 0.90 LMNA (0.68) ALDH1A1TSHRESR1LMNAHPGD
Padimate A SCHEMBL15372 0.88 ALDH1A1 (0.65) ALDH1A1TSHRESR1LMNAHPGD
SCHEMBL16231260 0.87 ALDH1A1 (0.61) ALDH1A1TSHRESR1TDP1LMNA
SCHEMBL7536250 0.87 ALDH1A1 (0.68) ALDH1A1TSHRESR1LMNAHPGD
SCHEMBL10885904 0.87 ALDH1A1 (0.68) ALDH1A1TSHRESR1LMNAHPGD
SCHEMBL4595623 0.87 ALDH1A1 (0.68) ALDH1A1TSHRESR1LMNAHPGD
SCHEMBL873127 0.87 ALDH1A1 (0.68) ALDH1A1TSHRESR1LMNAHPGD
Padimate A SCHEMBL28088966 0.87 ALDH1A1 (0.63) ALDH1A1TSHRESR1LMNAHPGD
SCHEMBL194303 0.87 ALDH1A1 (0.68) ALDH1A1TSHRESR1LMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 219 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12622847-B2 Organosilicon compound and dental composition containing same KURARAY NORITAKE DENTAL INC. (JP) 2026-05-12 US disclosed
EP-4029839-B1 GLASS POWDER AND CHEMICAL POLYMERIZATION INITIATOR G C DENTAL IND CORP (JP) 2026-05-06 EP disclosed
US-12600867-B2 Method of coating article, use for coating article, and polymerizable composition GC CORPORATION (JP) 2026-04-14 US disclosed
US-12569409-B2 Dental polymerizable composition GC CORPORATION (JP) 2026-03-10 US disclosed
US-12564543-B2 Dental composition KURARAY NORITAKE DENTAL INC. (JP) 2026-03-03 US disclosed
US-12527725-B2 Solvent-free dental adhesive composition KURARAY NORITAKE DENTAL INC. (JP) 2026-01-20 US disclosed
US-12478561-B2 Dental composition and dental restorative kit GC CORPORATION (JP) 2025-11-25 US disclosed
EP-4649938-A1 DENTAL COMPOSITION Kuraray Noritake Dental Inc. (JP) 2025-11-19 EP disclosed
US-12460021-B2 Glass powder and chemical polymerization initiator GC CORPORATION (JP) 2025-11-04 US disclosed
US-12377026-B2 Dental adhesive material kit KURARAY NORITAKE DENTAL INC. (JP) 2025-08-05 US disclosed
US-7615582-B2 One-pack type adhesive composition for dental use KURARAY MEDICAL INC. (JP) 2009-11-10 US disclosed
CN-1331894-C Photoepolymerization initiater TOKUYAMA CORP (JP) 2007-08-15 CN disclosed
US-20070100020-A1 One-pack type adhesive composition for dental use KURARAY MEDICAL INC. (JP) 2007-05-03 US disclosed
EP-1695685-A1 ONE-PACK TYPE ADHESIVE COMPOSITION FOR DENTAL USE Kuraray Medical Inc. (JP) 2006-08-30 EP disclosed
US-7084182-B2 Photopolymerization initiator TOKUYAMA CORPORATION (JP) 2006-08-01 US disclosed
EP-1457190-B1 Photopolymerization initiator TOKUYAMA CORP (JP) 2006-06-21 EP disclosed
CN-1537870-A Photoepolymerization initiater ��ʽ�����ɽ 2004-10-20 CN disclosed
US-20040180983-A1 Photopolymerization initiator TOKUYAMA DENTAL CORPORATION (JP) 2004-09-16 US disclosed
EP-1457190-A1 Photopolymerization initiator Tokuyama Corporation (JP) 2004-09-15 EP disclosed
EP-0475086-A1 Photo-sensitive polymer composition HITACHI, LTD. (JP) 1992-03-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12569409-B2 Dental polymerizable composition VCL, ACR, TPO ALDH1A1 1945/4885TSHR 312/4885ESR1 4502/4885
US-12600867-B2 Method of coating article, use for coating article, and polymerizable composition SARS1, SPIN1, ESPL1 ALDH1A1 3420/4885TSHR 4346/4885ESR1 2600/4885
US-12527725-B2 Solvent-free dental adhesive composition CDH1, ITGA1, ITGB8 ALDH1A1 1885/4885TSHR 3896/4885ESR1 1345/4885
US-20070100020-A1 One-pack type adhesive composition for dental use CDH1, COL1A1, COL2A1 ALDH1A1 419/4885TSHR 4681/4885ESR1 1004/4885
US-12564543-B2 Dental composition CAD, ARCN1, MAT1A ALDH1A1 306/4885TSHR 4074/4885ESR1 1812/4885
US-12622847-B2 Organosilicon compound and dental composition containing same MSL1, ITGA1, ITGAL ALDH1A1 668/4885TSHR 4185/4885ESR1 1639/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.