SCHEMBL148292

SCHEMBL148292

CCCOC(=O)c1ccc(N(CC)CC)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.64
TSHR P16473 4/20 0.64
ESR1 P03372 2/20 0.64
TDP1 Q9NUW8 2/20 0.64
CHRM1 P11229 1/20 0.64
SLC6A2 P23975 1/20 0.64
KDR P35968 1/20 0.64
LMNA P02545 5/20 0.61
HPGD P15428 3/20 0.55
SMN1; SMN2 Q16637 3/20 0.54
KMT2A Q03164 3/20 0.53
MEN1 O00255 2/20 0.53
STS P08842 1/20 0.53
RAB9A P51151 2/20 0.52
CYP1A2 P05177 2/20 0.51
CYP2D6 P10635 2/20 0.51
CYP2C19 P33261 2/20 0.51
MAPK1 P28482 1/20 0.51
NR1H2 P55055 1/20 0.51
RNASEL Q05823 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15315056 0.91 MAPT (0.58) ALDH1A1TSHRESR1TDP1CHRM1
SCHEMBL7601276 0.89 ALDH1A1 (0.63) ALDH1A1TSHRESR1LMNAHPGD
SCHEMBL5709852 0.87 ALDH1A1 (0.66) ALDH1A1TSHRESR1LMNAHPGD
SCHEMBL65692 0.86 CA12 (0.61) ALDH1A1TSHRESR1TDP1LMNA
SCHEMBL49950 0.85 ALDH1A1 (0.84) ALDH1A1TSHRESR1TDP1CHRM1
SCHEMBL63768 0.85 LMNA (0.55) ALDH1A1TSHRESR1TDP1CHRM1
SCHEMBL147844 0.84 ALDH1A1 (0.66) ALDH1A1TSHRESR1TDP1CHRM1
SCHEMBL3676309 0.84 PKM (0.61) ALDH1A1TSHRESR1TDP1CHRM1
SCHEMBL27647504 0.83 ALDH1A1 (0.81) ALDH1A1TSHRESR1TDP1CHRM1
SCHEMBL28758641 0.83 ALDH1A1 (0.81) ALDH1A1TSHRESR1TDP1CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4029839-B1 GLASS POWDER AND CHEMICAL POLYMERIZATION INITIATOR G C DENTAL IND CORP (JP) 2026-05-06 EP disclosed
US-12600867-B2 Method of coating article, use for coating article, and polymerizable composition GC CORPORATION (JP) 2026-04-14 US disclosed
US-12569409-B2 Dental polymerizable composition GC CORPORATION (JP) 2026-03-10 US disclosed
US-12478561-B2 Dental composition and dental restorative kit GC CORPORATION (JP) 2025-11-25 US disclosed
US-12460021-B2 Glass powder and chemical polymerization initiator GC CORPORATION (JP) 2025-11-04 US disclosed
US-20250223219-A1 GLASS COMPOSITION GC CORPORATION (JP) 2025-07-10 US disclosed
US-20250213435-A1 DENTAL ADHESIVE COMPOSITION GC CORPORATION (JP) 2025-07-03 US disclosed
EP-3884921-B1 DENTAL POLYMERIZABLE COMPOSITION G C DENTAL IND CORP (JP) 2025-07-02 EP disclosed
EP-3884922-B1 DENTAL POLYMERIZABLE COMPOSITION G C DENTAL IND CORP (JP) 2025-06-18 EP disclosed
US-12329832-B2 Dental polymerizable composition GC CORPORATION (JP) 2025-06-17 US disclosed
US-20110172323-A1 PHOTOPOLYMERIZABLE COMPOSITIONS TOKUYAMA DENTAL CORPORATION (JP) 2011-07-14 US disclosed
EP-2280032-A1 PHOTOPOLYMERIZABLE COMPOSITIONS Tokuyama Dental Corporation (JP) 2011-02-02 EP disclosed
US-20100216096-A1 DENTAL FILLING/RESTORATION KIT TOKUYAMA DENTAL CORPORATION (JP) 2010-08-26 US disclosed
EP-2163234-A1 DENTAL FILLING/RESTORATION KIT Tokuyama Dental Corporation (JP) 2010-03-17 EP disclosed
US-7381423-B2 Use of nanodispersions in cosmetic end formulations CIBA SPECIALTY CHEMICALS CORP. (US) 2008-06-03 US disclosed
US-7084182-B2 Photopolymerization initiator TOKUYAMA CORPORATION (JP) 2006-08-01 US disclosed
EP-1457190-B1 Photopolymerization initiator TOKUYAMA CORP (JP) 2006-06-21 EP disclosed
US-20040180983-A1 Photopolymerization initiator TOKUYAMA DENTAL CORPORATION (JP) 2004-09-16 US disclosed
EP-1457190-A1 Photopolymerization initiator Tokuyama Corporation (JP) 2004-09-15 EP disclosed
EP-0475086-A1 Photo-sensitive polymer composition HITACHI, LTD. (JP) 1992-03-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12569409-B2 Dental polymerizable composition VCL, ACR, TPO ALDH1A1 1945/4885TSHR 312/4885ESR1 4502/4885
US-12600867-B2 Method of coating article, use for coating article, and polymerizable composition SARS1, SPIN1, ESPL1 ALDH1A1 3420/4885TSHR 4346/4885ESR1 2600/4885
US-20250213435-A1 DENTAL ADHESIVE COMPOSITION ITGA1, ITGA2, ITGB6 ALDH1A1 641/4885TSHR 2369/4885ESR1 92/4885
US-20110172323-A1 PHOTOPOLYMERIZABLE COMPOSITIONS RARA, RARB, RARG ALDH1A1 188/4885TSHR 4636/4885ESR1 510/4885
US-12329832-B2 Dental polymerizable composition DTYMK, DEK, VRK2 ALDH1A1 1052/4885TSHR 2191/4885ESR1 3540/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.