SCHEMBL1490590

SCHEMBL1490590

CC(C)(O)C(C)(C)OB(O)c1ccc(CN)cc1

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
F11 P03951 1/20 0.47
ABAT P80404 1/20 0.35
LOXL2 Q9Y4K0 4/20 0.35
F10 P00742 1/20 0.35
NOS3 P29474 2/20 0.33
NOS1 P29475 2/20 0.33
NOS2 P35228 2/20 0.33
KEAP1 Q14145 1/20 0.33
NFE2L2 Q16236 1/20 0.33
HRH3 Q9Y5N1 1/20 0.33
LPL P06858 2/20 0.32
LIPG Q9Y5X9 2/20 0.32
ST14 Q9Y5Y6 3/20 0.32
KDM4E B2RXH2 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
MAOB P27338 1/20 0.30
PSIP1 O75475 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9986342 0.85 PPARG (0.37) NOS3NOS1LPLLIPG
SCHEMBL3036815 0.84 ENPP2 (0.39) F11LOXL2F10NOS3NOS1
SCHEMBL1129027 0.83 LPL (0.32) LPLLIPG
SCHEMBL18705952 0.83 LPL (0.32) LPLLIPG
SCHEMBL54815 0.81 MAPK1 (0.32)
SCHEMBL1774449 0.81 LTA4H (0.40) SMN1; SMN2
SCHEMBL17315637 0.81 RXRA (0.42) KDM4E
SCHEMBL3393899 0.81 HRH3 (0.40) NOS3NOS1NOS2HRH3LPL
SCHEMBL6607206 0.81 PPARG (0.34) LPLLIPG
SCHEMBL19433226 0.80 CA2 (0.42) LPLLIPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115154422-B CD44 targeting and ROS response nano micelle pharmaceutical composition, and preparation method and application thereof 四川大学 2023-07-07 CN claimed
CN-115154422-A CD44 targeting and ROS responding nano micelle medicine composition, preparation method and application 四川大学 2022-10-11 CN claimed
US-12611617-B2 Chromatographic columns and separation devices comprising a superficially porous material; and use thereof for supercritical fluid chromatography and other chromatography WATERS TECHNOLOGIES CORPORATION (US) 2026-04-28 US disclosed
US-20240293799-A1 CHROMATOGRAPHIC MATERIALS WATERS TECHNOLOGIES CORPORATION (US) 2024-09-05 US disclosed
US-11992824-B2 Chromatographic materials WATERS TECHNOLOGIES CORPORATION 2024-05-28 US disclosed
US-20230312577-A1 DUAL KINASE-BROMODOMAIN INHIBITORS MONASH UNIVERSITY (AU) 2023-10-05 US disclosed
CN-115154422-B CD44 targeting and ROS response nano micelle pharmaceutical composition, and preparation method and application thereof 四川大学 2023-07-07 CN disclosed
US-20230173406-A1 CHROMATOGRAPHIC COLUMNS AND SEPARATION DEVICES COMPRISING A SUPERFICIALLY POROUS MATERIAL; AND USE THEREOF FOR SUPERCRITICAL FLUID CHROMATOGRAPHY AND OTHER CHROMATOGRAPHY WATERS TECHNOLOGIES CORPORATION (US) 2023-06-08 US disclosed
EP-4165045-A1 DUAL KINASE-BROMODOMAIN INHIBITORS Monash University (AU) 2023-04-19 EP disclosed
US-11577179-B2 Chromatographic columns and separation devices comprising a superficially porous material; and use thereof for supercritical fluid chromatography and other chromatography WATERS TECHNOLOGIES CORPORATION (US) 2023-02-14 US disclosed
CN-115154422-A CD44 targeting and ROS responding nano micelle medicine composition, preparation method and application 四川大学 2022-10-11 CN disclosed
EP-3936226-A2 CHROMATOGRAPHIC COLUMNS AND SEPARATION DEVICES COMPRISING A SUPERFICIALLY POROUS MATERIAL; AND USE THEREOF FOR SUPERCRITICAL FLUID CHROMATOGRAPHY AND OTHER CHROMATOGRAPHY Waters Technologies Corporation (US) 2022-01-12 EP disclosed
US-20210331138-A1 CHROMATOGRAPHIC MATERIALS WATERS TECHNOLOGIES CORPORATION (US) 2021-10-28 US disclosed
CN-111205310-A Heterocyclic fused pyrimidine derivative, and pharmaceutical composition and application thereof 上海迪诺医药科技有限公司 2020-05-29 CN disclosed
US-10265679-B2 Chromatographic materials WATERS TECHNOLOGIES CORPORATION (US) 2019-04-23 US disclosed
US-20180326399-A1 CHROMATOGRAPHIC MATERIALS WATERS TECHNOLOGIES CORPORATION 2018-11-15 US disclosed
US-20160184736-A1 CHROMATOGRAPHIC COLUMNS AND SEPARATION DEVICES COMPRISING A SUPERFICIALLY POROUS MATERIAL; AND USE THEREOF FOR SUPERCRITICAL FLUID CHROMATOGRAPHY AND OTHER CHROMATOGRAPHY WATERS TECHNOLOGIES CORPORATION (US) 2016-06-30 US disclosed
WO-2015140566-A1 PYRAZOLO-PYRIMIDINES AS INHIBITORS OF BTK REDX PHARMA PLC (GB) 2015-09-24 WO disclosed
US-7897609-B2 Aryl substituted imidazonaphthyridines 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-03-01 US disclosed
US-20070219228-A1 Aryl substituted imidazonaphthyridines 3M INNOVATIVE PROPERTIES COMPANY 2007-09-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12611617-B2 Chromatographic columns and separation devices comprising a superficially porous material; and use thereof for supercritical fluid chromatography and other chromatography F11, F12, F2 F11 1/4885ABAT 4788/4885LOXL2 1442/4885
US-20180326399-A1 CHROMATOGRAPHIC MATERIALS HAX1, CXCR1, YBX1 F11 6/4885ABAT 4406/4885LOXL2 2586/4885
US-20230173406-A1 CHROMATOGRAPHIC COLUMNS AND SEPARATION DEVICES COMPRISING A SUPERFICIALLY POROUS MATERIAL; AND USE THEREOF FOR SUPERCRITICAL FLUID CHROMATOGRAPHY AND OTHER CHROMATOGRAPHY SPECC1L, CCL5, CCR5 F11 680/4885ABAT 4790/4885LOXL2 2920/4885
US-20240293799-A1 CHROMATOGRAPHIC MATERIALS HAX1, CXCR1, YBX1 F11 6/4885ABAT 4406/4885LOXL2 2586/4885
US-20070219228-A1 Aryl substituted imidazonaphthyridines IL2, IRF3, EIF2AK2 F11 4805/4885ABAT 174/4885LOXL2 3916/4885
US-20230312577-A1 DUAL KINASE-BROMODOMAIN INHIBITORS MAP2K2, BRPF3, BRDT F11 4155/4885ABAT 3540/4885LOXL2 1750/4885
US-20160184736-A1 CHROMATOGRAPHIC COLUMNS AND SEPARATION DEVICES COMPRISING A SUPERFICIALLY POROUS MATERIAL; AND USE THEREOF FOR SUPERCRITICAL FLUID CHROMATOGRAPHY AND OTHER CHROMATOGRAPHY SPECC1L, CCL5, CCR5 F11 680/4885ABAT 4790/4885LOXL2 2920/4885
US-11577179-B2 Chromatographic columns and separation devices comprising a superficially porous material; and use thereof for supercritical fluid chromatography and other chromatography SEPTIN9, PORCN, SPECC1L F11 3232/4885ABAT 4596/4885LOXL2 2884/4885
US-20210331138-A1 CHROMATOGRAPHIC MATERIALS HAX1, CXCR1, YBX1 F11 6/4885ABAT 4406/4885LOXL2 2586/4885
US-11992824-B2 Chromatographic materials HAX1, CXCR1, YBX1 F11 6/4885ABAT 4406/4885LOXL2 2586/4885
US-10265679-B2 Chromatographic materials HAX1, CXCR1, YBX1 F11 6/4885ABAT 4406/4885LOXL2 2586/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.