Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | LPL | P06858 | 2/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6607206 | 0.95 | PPARG (0.34) | PPARGPPARALPLLIPGPRSS1 | |
| SCHEMBL1129027 | 0.85 | LPL (0.32) | LPLLIPG | |
| SCHEMBL18705952 | 0.85 | LPL (0.32) | LPLLIPG | |
| SCHEMBL1490590 | 0.85 | F11 (0.47) | LPLLIPGNOS3NOS1 | |
| SCHEMBL1774449 | 0.82 | LTA4H (0.40) | PPARGPPARALTA4H | |
| SCHEMBL17315637 | 0.82 | RXRA (0.42) | EPHX2TSHRCA2 | |
| SCHEMBL3393899 | 0.82 | HRH3 (0.40) | LPLLIPGTSHRNOS3NOS1 | |
| SCHEMBL19433226 | 0.82 | CA2 (0.42) | LPLLIPGENPP2TSHRCA1 | |
| SCHEMBL15194641 | 0.81 | CA1 (0.56) | LPLLIPGCA1CA2 | |
| SCHEMBL3234120 | 0.81 | ENPP2 (0.37) | LPLLIPGENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4129978-A1 | NANOPARTICLES COMPRISING DRUG DIMERS, AND USE THEREOF | Therabest Co., Ltd. (KR) | 2023-02-08 | — | — | EP | claimed |
| US-12377052-B2 | Dual-responsive nanoparticles for enhanced antibacterial efficacy | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2025-08-05 | — | — | US | disclosed |
| EP-4273143-B1 | DERIVATIVE OF 2,5-DIKETOPIPERAZINE COMPOUND, AND PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | DALIAN WZ PROBIOTICS AD HEALTH CO LTD (CN) | 2025-05-21 | — | — | EP | disclosed |
| US-20240261309-A1 | RETINOIC ACID PRECURSOR AND ANTICANCER DRUG COMPOSITION COMPRISING SAME | INDUSTRIAL COOPERATION FOUNDATION JEONBUK NATIONAL UNIVERSITY (KR) | 2024-08-08 | — | — | US | disclosed |
| US-20240140941-A1 | DERIVATIVE OF 2,5-DIKETOPIPERAZINE COMPOUND, AND PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | DALIAN WZ PROBIOTICS AD HEALTH CO., LTD (CN) | 2024-05-02 | — | — | US | disclosed |
| US-20230383035-A1 | PROTEIN-POLYMER NANOASSEMBLIES AND INTRACELLULAR PROTEIN DELIVERY | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-11-30 | — | — | US | disclosed |
| WO-2023220671-A1 | PRODRUGS USEFUL FOR REDUCING ANTHRACYCLINE CARDIOTOXICITY | WAKE FOREST UNIVERSITY HEALTH SCIENCES (US) | 2023-11-16 | — | — | WO | disclosed |
| EP-4273143-A1 | DERIVATIVE OF 2,5-DIKETOPIPERAZINE COMPOUND, AND PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | Dalian WZ Probiotics AD Health Co., Ltd (CN) | 2023-11-08 | — | — | EP | disclosed |
| US-11746172-B2 | Protein-polymer nanoassemblies and intracellular protein delivery | UNIVERSITY OF MASSACHUSETTS (US) | 2023-09-05 | — | — | US | disclosed |
| US-20230120021-A1 | NANOPARTICLES COMPRISING DRUG DIMERS, AND USE THEREOF | INDUSTRIAL COOPERATION FOUNDATION JEONBUK NATIONAL UNIVERSITY (KR) | 2023-04-20 | — | — | US | disclosed |
| US-20140255311-A1 | BIOCOMPATIBLE POLYMERIC NANOPARTICLES DEGRADE AND RELEASE CARGO IN RESPONSE TO BIOLOGICALLY RELEVANT LEVELS OF HYDROGEN PEROXIDE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-09-11 | — | — | US | disclosed |
| EP-2755965-A1 | NOVEL IMIDAZOLE AMINES AS MODULATORS OF KINASE ACTIVITY | Merck Patent GmbH (DE) | 2014-07-23 | — | — | EP | disclosed |
| EP-2704573-A1 | AMINOMETHYL BIARYL BENZOTRIAZOLE DERIVATIVES | Merck Sharp & Dohme Corp. (US) | 2014-03-12 | — | — | EP | disclosed |
| US-20140066443-A1 | AMINOMETHYL BIARYL BENZOTRIAZOLE DERIVATIVES | MERCK SHARP & DOHME LLC | 2014-03-06 | — | — | US | disclosed |
| WO-2013173834-A2 | TRIGGER-RESPONSIVE CHAIN-SHATTERING POLYMERS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2013-11-21 | — | — | WO | disclosed |
| WO-2013040059-A1 | NOVEL IMIDAZOLE AMINES AS MODULATORS OF KINASE ACTIVITY | MERCK PATENT GMBH (DE) | 2013-03-21 | — | — | WO | disclosed |
| WO-2012151136-A1 | AMINOMETHYL BIARYL BENZOTRIAZOLE DERIVATIVES | MERCK SHARP & DOHME CORP. (US) | 2012-11-08 | — | — | WO | disclosed |
| WO-2012123076-A1 | FERROCENE-BASED COMPOUNDS AND THEIR USE AS ROS REGULATING PRODRUGS | Ruprecht-Karls-Universität Heidelberg (DE) | 2012-09-20 | — | — | WO | disclosed |
| EP-2497775-A1 | Ferrocene-based compounds and their use as ROS regulating prodrugs | Ruprecht-Karls-Universität Heidelberg (DE) | 2012-09-12 | — | — | EP | disclosed |
| US-20110312905-A1 | STIMULUS-TRIGGERED PRODRUGS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140255311-A1 | BIOCOMPATIBLE POLYMERIC NANOPARTICLES DEGRADE AND RELEASE CARGO IN RESPONSE TO BIOLOGICALLY RELEVANT LEVELS OF HYDROGEN PEROXIDE | DBH, LPO, HAO2 | PPARG 3938/4885PPARA 3707/4885LPL 3076/4885 |
| US-11746172-B2 | Protein-polymer nanoassemblies and intracellular protein delivery | NUP205, PHLPP2, MSN | PPARG 4376/4885PPARA 4266/4885LPL 3929/4885 |
| US-20230120021-A1 | NANOPARTICLES COMPRISING DRUG DIMERS, AND USE THEREOF | ABCB1, PIN1, ABCG2 | PPARG 4424/4885PPARA 4153/4885LPL 4629/4885 |
| US-20240140941-A1 | DERIVATIVE OF 2,5-DIKETOPIPERAZINE COMPOUND, AND PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | WEE1, WEE2, CYP51A1 | PPARG 2591/4885PPARA 2385/4885LPL 2993/4885 |
| US-20140066443-A1 | AMINOMETHYL BIARYL BENZOTRIAZOLE DERIVATIVES | GRM2, GRM3, GRIN2C | PPARG 159/4885PPARA 352/4885LPL 3678/4885 |
| US-12377052-B2 | Dual-responsive nanoparticles for enhanced antibacterial efficacy | SBDS, LRBA, MAP2K1 | PPARG 4133/4885PPARA 3124/4885LPL 4211/4885 |
| US-20240261309-A1 | RETINOIC ACID PRECURSOR AND ANTICANCER DRUG COMPOSITION COMPRISING SAME | RARA, RARB, RARG | PPARG 1824/4885PPARA 1917/4885LPL 4344/4885 |
| US-20230383035-A1 | PROTEIN-POLYMER NANOASSEMBLIES AND INTRACELLULAR PROTEIN DELIVERY | NUP205, PHLPP2, MSN | PPARG 4376/4885PPARA 4266/4885LPL 3929/4885 |
| US-20110312905-A1 | STIMULUS-TRIGGERED PRODRUGS | PREP, ADAM10, DNPEP | PPARG 2531/4885PPARA 2577/4885LPL 564/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.