SCHEMBL1730358

SCHEMBL1730358

O=S(=O)([O-])c1c(O)ccc2ccccc12.[Na+]

nearest known ligand 0.50

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 1/20 0.50
PTPN22 Q9Y2R2 1/20 0.48
POLB P06746 1/20 0.46
HKDC1 Q2TB90 1/20 0.45
G6PD P11413 1/20 0.45
MAPT P10636 3/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
HSD17B10 Q99714 2/20 0.44
CYP1A2 P05177 2/20 0.44
USP2 O75604 1/20 0.44
PAK1 Q13153 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
HCRTR1 O43613 1/20 0.44
HSD17B2 P37059 1/20 0.42
KDM4E B2RXH2 2/20 0.42
ALDH1A1 P00352 2/20 0.42
GAA P10253 2/20 0.42
GLA P06280 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3692997 0.96 ERN1 (0.50) ERN1PTPN22POLBHKDC1G6PD
SCHEMBL2761906 0.96 ERN1 (0.50) ERN1PTPN22POLBHKDC1G6PD
SCHEMBL11046405 0.82 ERN1 (0.55) ERN1PTPN22POLBHKDC1G6PD
SCHEMBL29625740 0.82 ERN1 (0.55) ERN1PTPN22POLBHKDC1G6PD
SCHEMBL564094 0.81 ERN1 (0.53) ERN1PTPN22POLBHKDC1G6PD
SCHEMBL3035364 0.81 ERN1 (0.53) ERN1PTPN22POLBHKDC1G6PD
SCHEMBL7203177 0.79 ERN1 (0.52) ERN1PTPN22POLBHKDC1G6PD
SCHEMBL1730362 0.79 ERN1 (0.52) ERN1PTPN22POLBHKDC1G6PD
SCHEMBL20885914 0.79 ERN1 (0.52) ERN1PTPN22POLBHKDC1G6PD
SCHEMBL3233249 0.79 CA1 (0.41) ERN1HSD17B10ALDH1A1HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1584 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-214916020-U Alkali fusion device for producing 2-naphthol and 2-naphthol production system 内蒙古美力坚科技化工有限公司 2021-11-30 CN claimed
CN-106459939-B Lipase variants and polynucleotides encoding same 诺维信公司 2026-05-22 CN disclosed
US-12630812-B2 Subtilase variants and polynucleotides encoding same NOVOZYMES A/S (DK) 2026-05-19 US disclosed
US-20260132388-A1 LIPASE VARIANTS AND MICROCAPSULE COMPOSITIONS COMPRISING SUCH LIPASE VARIANTS NOVOZYMES A/S (DK) 2026-05-14 US disclosed
EP-4739760-A1 WASHING METHOD FOR REMOVING PROTEINACEOUS STAINS Novozymes A/S (DK) 2026-05-13 EP disclosed
CN-122029266-A Use of xyloglucanases for replacing optical brighteners 诺维信公司 2026-05-12 CN disclosed
EP-3607038-B1 CLEANING COMPOSITIONS AND USES THEREOF NOVOZYMES AS (DK) 2026-05-06 EP disclosed
EP-4735563-A1 DETERGENT COMPOSITION COMPRISING LIPASES Novozymes A/S (DK) 2026-05-06 EP disclosed
EP-3708660-B1 POLYPEPTIDES NOVOZYMES AS (DK) 2026-04-29 EP disclosed
EP-4729596-A2 DETERGENT COMPOSITION COMPRISING AMYLASE AND PROTEASE VARIANTS Novozymes A/S (DK) 2026-04-22 EP disclosed
US-7344236-B2 Ink-jet cloth printing ink and an ink-jet recording method KONICA-MINOLTA HOLDINGS, INC. (JP) 2008-03-18 US disclosed
US-7341622-B2 Ink-jet ink production method and ink-jet recording method KONICA MINOLTA HOLDINGS, INC. (JP) 2008-03-11 US disclosed
US-20050217536-A1 Ink-jet ink production method and ink-jet recording method KONICA MINOLTA HOLDINGS, INC. (JP) 2005-10-06 US disclosed
US-20050057631-A1 Ink-jet cloth printing ink and an ink-jet recording method KONICA MINOLTA HOLDINGS, INC. (JP) 2005-03-17 US disclosed
EP-1514969-A1 An ink-jet cloth printing ink and an ink-jet recording method KONICA MINOLTA HOLDINGS, INC. (JP) 2005-03-16 EP disclosed
US-6733113-B2 Ink-jet recording method and ink-jet recording apparatus KONICA CORPORATION (JP) 2004-05-11 US disclosed
US-20030043238-A1 Ink-jet recording method and ink-jet recording apparatus KONICA CORPORATION (JP) 2003-03-06 US disclosed
EP-0718704-A1 Electrophotographic toner and developer MITA INDUSTRIAL CO. LTD. (JP) 1996-06-26 EP disclosed
US-4390340-A Tanning agent, its preparation and its use for retanning BASF AKTIENGESELLSCHAFT (DE) 1983-06-28 US disclosed
US-4120960-A DIURETICS, SALURESIS THE BOOTS COMPANY LIMITED (GB) 1978-10-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260132388-A1 LIPASE VARIANTS AND MICROCAPSULE COMPOSITIONS COMPRISING SUCH LIPASE VARIANTS LIPE, LPL, PNLIP ERN1 1645/4885PTPN22 1563/4885POLB 1126/4885
US-12630812-B2 Subtilase variants and polynucleotides encoding same RNASE1, PEPD, DPP9 ERN1 431/4885PTPN22 927/4885POLB 550/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.