SCHEMBL18383151

SCHEMBL18383151

N#Cc1cc(N2C(=O)c3ccc4c5c(ccc(c35)C2=O)C(=O)N(c2ccc(C#N)c(C#N)c2)C4=O)ccc1N

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.44
USP2 O75604 3/20 0.44
KEAP1 Q14145 3/20 0.44
NFE2L2 Q16236 3/20 0.44
MEN1 O00255 3/20 0.44
L3MBTL1 Q9Y468 1/20 0.42
POLB P06746 2/20 0.41
APAF1 O14727 1/20 0.41
NPC1 O15118 3/20 0.41
RAB9A P51151 3/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA9 Q16790 1/20 0.41
ALDH1A1 P00352 5/20 0.40
KDM4E B2RXH2 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
MAPT P10636 1/20 0.40
HTT P42858 1/20 0.40
LMNA P02545 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23017534 0.91 POLB (0.41) KMT2AUSP2KEAP1NFE2L2MEN1
SCHEMBL5574945 0.91 POLB (0.49) KMT2AUSP2KEAP1NFE2L2MEN1
SCHEMBL18436037 0.87 POLB (0.45) KMT2AUSP2KEAP1NFE2L2MEN1
SCHEMBL17995366 0.84 POLB (0.42) KMT2AUSP2KEAP1NFE2L2MEN1
SCHEMBL18215026 0.83 POLB (0.41) KMT2AUSP2KEAP1NFE2L2MEN1
SCHEMBL31513527 0.83 NPC1 (0.44) KMT2AUSP2KEAP1NFE2L2MEN1
SCHEMBL20028955 0.83 MEN1 (0.45) KMT2AUSP2KEAP1NFE2L2MEN1
SCHEMBL25575134 0.83 MEN1 (0.45) KMT2AUSP2KEAP1NFE2L2MEN1
SCHEMBL18214082 0.81 POLB (0.38) KMT2AUSP2KEAP1NFE2L2MEN1
SCHEMBL20980539 0.80 ALDH1A1 (0.42) KMT2AUSP2KEAP1NFE2L2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230263048-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-08-17 US disclosed
US-20230200212-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-06-22 US disclosed
US-11616203-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-03-28 US disclosed
US-20220146812-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-05-12 US disclosed
US-20220106343-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-04-07 US disclosed
US-11228004-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-01-18 US disclosed
US-20210376261-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-12-02 US disclosed
US-RE48809-E1 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-11-02 US disclosed
US-20210206785-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-07-08 US disclosed
US-11024807-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-06-01 US disclosed
US-20190315788-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-10-17 US disclosed
US-20190296252-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-09-26 US disclosed
US-20190280214-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2019-09-12 US disclosed
US-20180145268-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2018-05-24 US disclosed
US-9978956-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-05-22 US disclosed
US-20180134954-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2018-05-17 US disclosed
US-20180134718-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2018-05-17 US disclosed
US-9929360-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-03-27 US disclosed
US-20180083207-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2018-03-22 US disclosed
US-20170018721-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-01-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (15 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180083207-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ZFR, SOD1, NDUFS2 KMT2A 3400/4885USP2 4615/4885KEAP1 1563/4885
US-11616203-B2 Organic electroluminescent materials and devices ICOSLG, APOL1, OXA1L KMT2A 3158/4885USP2 4337/4885KEAP1 1094/4885
US-11228004-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, ICOSLG KMT2A 843/4885USP2 3894/4885KEAP1 900/4885
US-20220106343-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ICOSLG KMT2A 2109/4885USP2 4559/4885KEAP1 631/4885
US-20230200212-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, SIRT2, OCIAD1 KMT2A 2417/4885USP2 2238/4885KEAP1 1054/4885
US-20170018721-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES AOX1, RPS4X, MLX KMT2A 2690/4885USP2 3854/4885KEAP1 3490/4885
US-20230263048-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, ODC1 KMT2A 3598/4885USP2 4793/4885KEAP1 967/4885
US-20210376261-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, TPO KMT2A 1926/4885USP2 3721/4885KEAP1 928/4885
US-20180134954-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OSBP, OCIAD1, OCIAD2 KMT2A 4600/4885USP2 4810/4885KEAP1 3861/4885
US-20190280214-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LEF1, OCIAD1, OCIAD2 KMT2A 2295/4885USP2 3286/4885KEAP1 1718/4885
US-20180134718-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, SLCO4C1 KMT2A 3996/4885USP2 4714/4885KEAP1 1468/4885
US-20210206785-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OSBP KMT2A 2169/4885USP2 4359/4885KEAP1 316/4885
US-20190296252-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES NR1D2, NR1D1, NR1H2 KMT2A 3186/4885USP2 4368/4885KEAP1 1760/4885
US-20190315788-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES L1CAM, LEF1, ZYX KMT2A 2042/4885USP2 4324/4885KEAP1 1160/4885
US-20180145268-A1 Organic Electroluminescent Materials and Devices OCIAD2, OCIAD1, SOAT2 KMT2A 3110/4885USP2 4312/4885KEAP1 1621/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.