SCHEMBL17995366

SCHEMBL17995366

C#Cc1ccc(N2C(=O)c3ccc4c5c(ccc(c35)C2=O)C(=O)N(c2ccc(C#N)c(C#N)c2)C4=O)cc1C#N

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 4/20 0.42
APAF1 O14727 1/20 0.42
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
ALDH1A1 P00352 4/20 0.39
HPGD P15428 3/20 0.39
LMNA P02545 2/20 0.39
CYP1A2 P05177 2/20 0.39
CYP2C19 P33261 2/20 0.39
CYP2C9 P11712 1/20 0.39
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
KDM4E B2RXH2 2/20 0.36
MAPK1 P28482 2/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
AR P10275 2/20 0.35
ESR1 P03372 1/20 0.34
ESR2 Q92731 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5574945 0.92 POLB (0.49) POLBAPAF1NPC1RAB9AALDH1A1
SCHEMBL18212393 0.91 POLB (0.38) POLBAPAF1NPC1RAB9AALDH1A1
SCHEMBL18211823 0.88 POLB (0.34) POLBAPAF1NPC1RAB9AALDH1A1
SCHEMBL18215026 0.84 POLB (0.41) POLBAPAF1NPC1RAB9AALDH1A1
SCHEMBL31513527 0.84 NPC1 (0.44) POLBAPAF1NPC1RAB9AALDH1A1
SCHEMBL23017534 0.84 POLB (0.41) POLBAPAF1NPC1RAB9AALDH1A1
SCHEMBL25575134 0.84 MEN1 (0.45) POLBAPAF1NPC1RAB9AALDH1A1
SCHEMBL20028955 0.84 MEN1 (0.45) POLBAPAF1NPC1RAB9AALDH1A1
SCHEMBL18383151 0.84 KMT2A (0.44) POLBAPAF1NPC1RAB9AALDH1A1
SCHEMBL18214082 0.80 POLB (0.38) POLBAPAF1NPC1RAB9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 306 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12048237-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-07-23 US disclosed
US-20240244955-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-07-18 US disclosed
US-12041846-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-07-16 US disclosed
US-12035618-B2 Electroluminescent devices UNIVERSAL DISPLAY CORPORATION (US) 2024-07-09 US disclosed
US-12035613-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-07-09 US disclosed
US-12035614-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-07-09 US disclosed
US-20240218004-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-07-04 US disclosed
US-20240224782-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-07-04 US disclosed
US-20240224783-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-07-04 US disclosed
US-20240209013-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-06-27 US disclosed
US-20160285016-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-09-29 US disclosed
US-20160260913-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-09-08 US disclosed
US-20160260908-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERAL DISPLAY CORPORATION (US) 2016-09-08 US disclosed
US-20160260909-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2016-09-08 US disclosed
US-20160254457-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2016-09-01 US disclosed
US-20160254460-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-09-01 US disclosed
US-20160240799-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-08-18 US disclosed
US-20160240800-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-08-18 US disclosed
US-20160240792-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2016-08-18 US disclosed
US-20160233429-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2016-08-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (19 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160260908-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, JUND POLB 2258/4885APAF1 3385/4885NPC1 226/4885
US-12035618-B2 Electroluminescent devices ELAVL1, ELAVL3, JUND POLB 1033/4885APAF1 3446/4885NPC1 1484/4885
US-20240244955-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES AOX1, SBDS, OCIAD2 POLB 585/4885APAF1 3998/4885NPC1 2114/4885
US-12041846-B2 Organic electroluminescent materials and devices OCIAD1, OSBP, OCIAD2 POLB 1008/4885APAF1 3025/4885NPC1 105/4885
US-20160254460-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES METTL3, L3MBTL3, CHRM1 POLB 4438/4885APAF1 3138/4885NPC1 3723/4885
US-20160240792-A1 Organic Electroluminescent Materials and Devices CBX2, DDX3X, CBX7 POLB 2434/4885APAF1 2043/4885NPC1 4260/4885
US-20160254457-A1 Organic Electroluminescent Materials and Devices PORCN, MAL2, CYBA POLB 47/4885APAF1 1418/4885NPC1 3762/4885
US-20240224783-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ICOSLG POLB 2524/4885APAF1 4321/4885NPC1 1965/4885
US-20240209013-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, SSB, L1CAM POLB 2714/4885APAF1 3377/4885NPC1 2692/4885
US-12048237-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, OSBP POLB 1485/4885APAF1 3302/4885NPC1 469/4885
US-20160233429-A1 Organic Electroluminescent Materials and Devices NBAS, TBCB, SLC1A2 POLB 1650/4885APAF1 4020/4885NPC1 1759/4885
US-12035614-B2 Organic electroluminescent materials and devices ZFR, SOD1, NDUFS2 POLB 390/4885APAF1 2673/4885NPC1 4236/4885
US-20160240799-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, OSBP2 POLB 3108/4885APAF1 2656/4885NPC1 2523/4885
US-20160260913-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES EML4, TYR, L1CAM POLB 898/4885APAF1 4591/4885NPC1 4195/4885
US-12035613-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, OTC POLB 1878/4885APAF1 4070/4885NPC1 1690/4885
US-20160240800-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OXER1, TECR, OR10J3 POLB 1700/4885APAF1 4786/4885NPC1 2843/4885
US-20160260909-A1 Organic Electroluminescent Materials and Devices PNMT, CYCS, NES POLB 3139/4885APAF1 2535/4885NPC1 4591/4885
US-20240224782-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES RER1, OCIAD2, OCIAD1 POLB 2201/4885APAF1 3852/4885NPC1 2566/4885
US-20240218004-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, CCND2 POLB 2336/4885APAF1 3549/4885NPC1 2560/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.