Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 5/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 4/20 | 0.42 |
| ▸ | HTR1A | P08908 | 4/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9944001 | 0.84 | HTT (0.34) | ALDH1A1CYP1A2CYP2D6KDM4EMAPT | |
| SCHEMBL4982126 | 0.84 | CYP3A4 (0.40) | ALDH1A1ADRA2CADRA2AADRA2BKDM4E | |
| SCHEMBL29699897 | 0.83 | ALDH1A1 (0.47) | ALDH1A1ADRA2CADRA2AADRA2BHTR1A | |
| SCHEMBL8961842 | 0.83 | ALDH1A1 (0.47) | ALDH1A1ADRA2CADRA2AADRA2BHTR1A | |
| SCHEMBL8961940 | 0.83 | ALDH1A1 (0.47) | ALDH1A1ADRA2CADRA2AADRA2BHTR1A | |
| SCHEMBL8503481 | 0.82 | GABRA1 (0.38) | ALDH1A1KDM4E | |
| SCHEMBL14457913 | 0.81 | XPO1 (0.38) | ALDH1A1ADRA2CHTR1AKCNH2ADRB2 | |
| SCHEMBL8961862 | 0.80 | ALDH1A1 (0.48) | ALDH1A1ADRA2CADRA2AADRA2BHTR1A | |
| SCHEMBL7240943 | 0.80 | RIPK1 (0.36) | — | |
| SCHEMBL2325955 | 0.80 | RIPK1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12251370-B2 | Small molecule inhibitors of the BfrB:Bfd interaction | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2025-03-18 | — | — | US | disclosed |
| US-20220031661-A1 | SMALL MOLECULE INHIBITORS OF THE BFRB:BFD INTERACTION | UNIVERSITY OF KANSAS | 2022-02-03 | — | — | US | disclosed |
| US-10266503-B1 | Sulfoxide ligand metal catalyzed oxidation of olefins | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2019-04-23 | — | — | US | disclosed |
| US-9656985-B2 | Surfactant-enabled transition metal-catalyzed chemistry | MYCELL TECHNOLOGIES, LLC (US) | 2017-05-23 | — | — | US | disclosed |
| US-9656986-B2 | Compositions comprising TPGS-750-M | MYCELL TECHNOLOGIES, LLC (US) | 2017-05-23 | — | — | US | disclosed |
| US-9656985-B2 | Surfactant-enabled transition metal-catalyzed chemistry | MYCELL TECHNOLOGIES, LLC (US) | 2017-05-23 | — | — | US | disclosed |
| US-9656986-B2 | Compositions comprising TPGS-750-M | MYCELL TECHNOLOGIES, LLC (US) | 2017-05-23 | — | — | US | disclosed |
| US-20170073322-A1 | Surfactant-Enabled Transition Metal-Catalyzed Chemistry | MYCELL TECHNOLOGIES, LLC (US) | 2017-03-16 | — | — | US | disclosed |
| US-20170073322-A1 | Surfactant-Enabled Transition Metal-Catalyzed Chemistry | MYCELL TECHNOLOGIES, LLC (US) | 2017-03-16 | — | — | US | disclosed |
| US-20160347677-A1 | Surfactant-Enabled Transition Metal-Catalyzed Chemistry | MYCELL TECH LLC (US) | 2016-12-01 | — | — | US | disclosed |
| US-20160347677-A1 | Surfactant-Enabled Transition Metal-Catalyzed Chemistry | MYCELL TECH LLC (US) | 2016-12-01 | — | — | US | disclosed |
| US-20160340332-A1 | Compositions Comprising TPGS-750-M | MYCELL TECH LLC (US) | 2016-11-24 | — | — | US | disclosed |
| US-20160340332-A1 | Compositions Comprising TPGS-750-M | MYCELL TECH LLC (US) | 2016-11-24 | — | — | US | disclosed |
| US-8785665-B2 | Surfactant-enabled transition metal-catalyzed chemistry | MYCELL TECHNOLOGIES, LLC (US) | 2014-07-22 | — | — | US | disclosed |
| US-8785665-B2 | Surfactant-enabled transition metal-catalyzed chemistry | MYCELL TECHNOLOGIES, LLC (US) | 2014-07-22 | — | — | US | disclosed |
| EP-2506970-A1 | SURFACTANT-ENABLED TRANSITION METAL-CATALYZED CHEMISTRY | Mycell Holdings Limited (US) | 2012-10-10 | — | — | EP | disclosed |
| WO-2011068895-A1 | SURFACTANT-ENABLED TRANSITION METAL-CATALYZED CHEMISTRY | MyCell Holdings Limited (US) | 2011-06-09 | — | — | WO | disclosed |
| US-20110130562-A1 | Surfactant-Enabled Transition Metal-Catalyzed Chemistry | MyCell Holdings Limited | 2011-06-02 | — | — | US | disclosed |
| US-20110130562-A1 | Surfactant-Enabled Transition Metal-Catalyzed Chemistry | MyCell Holdings Limited | 2011-06-02 | — | — | US | disclosed |
| US-20070155975-A1 | Cross-metathesis reaction of functionalized and substituted olefins using group 8 transition metal carbene complexes as metathesis catalysts | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2007-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070155975-A1 | Cross-metathesis reaction of functionalized and substituted olefins using group 8 transition metal carbene complexes as metathesis catalysts | OXER1, OSTC, OXSR1 | ALDH1A1 1898/4885ADRA2C 3139/4885ADRA2A 3516/4885 |
| US-12251370-B2 | Small molecule inhibitors of the BfrB:Bfd interaction | BLVRB, TFPI, ETFB | ALDH1A1 2584/4885ADRA2C 4693/4885ADRA2A 4712/4885 |
| US-20160340332-A1 | Compositions Comprising TPGS-750-M | S100A10, S100A6, TPR | ALDH1A1 4415/4885ADRA2C 4839/4885ADRA2A 4719/4885 |
| US-20170073322-A1 | Surfactant-Enabled Transition Metal-Catalyzed Chemistry | SOD1, SMURF1, MUC1 | ALDH1A1 3372/4885ADRA2C 4790/4885ADRA2A 4377/4885 |
| US-20110130562-A1 | Surfactant-Enabled Transition Metal-Catalyzed Chemistry | SOD1, SMURF1, MUC1 | ALDH1A1 3372/4885ADRA2C 4790/4885ADRA2A 4377/4885 |
| US-20160347677-A1 | Surfactant-Enabled Transition Metal-Catalyzed Chemistry | SOD1, SMURF1, MUC1 | ALDH1A1 3372/4885ADRA2C 4790/4885ADRA2A 4377/4885 |
| US-20220031661-A1 | SMALL MOLECULE INHIBITORS OF THE BFRB:BFD INTERACTION | BLVRB, TFPI, ETFB | ALDH1A1 2584/4885ADRA2C 4693/4885ADRA2A 4712/4885 |
| US-10266503-B1 | Sulfoxide ligand metal catalyzed oxidation of olefins | YAP1, ICOSLG, SPIN3 | ALDH1A1 1012/4885ADRA2C 784/4885ADRA2A 1935/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.