Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL195205 | 1.00 | CA12 (0.40) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9519385 | 0.90 | ALDH1A1 (0.40) | TDP1ALDH1A1MAPTATMHPGD | |
| SCHEMBL7805565 | 0.85 | CA12 (0.41) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL7811546 | 0.84 | RAB9A (0.43) | TDP1RAB9AALDH1A1DPP8DPP9 | |
| SCHEMBL10364355 | 0.83 | TDP1 (0.43) | TDP1RAB9AALDH1A1MAPTNPC1 | |
| SCHEMBL6398540 | 0.83 | TDP1 (0.43) | TDP1RAB9AALDH1A1MAPTNPC1 | |
| SCHEMBL8759638 | 0.83 | TDP1 (0.43) | TDP1RAB9AALDH1A1MAPTNPC1 | |
| SCHEMBL10370030 | 0.83 | RAB9A (0.42) | TDP1RAB9AALDH1A1DPP8DPP9 | |
| SCHEMBL7811544 | 0.82 | CCR5 (0.41) | TDP1RAB9AMAPTNPC1ATM | |
| SCHEMBL10370916 | 0.82 | RAB9A (0.42) | TDP1RAB9AALDH1A1DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8729260-B2 | Process for the preparation of carbapenem using cabapenem intermediates and recovery of cabapenem | SAVIOR LIFETEC CORPORATION (TW) | 2014-05-20 | — | — | US | disclosed |
| WO-2012114280-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF PYRROLIDINE THIOL DERIVATIVES USEFUL IN THE SYNTHESIS OF CARBAPENEM COMPOUNDS | ORCHID CHEMICALS AND PHARMACEUTICALS LIMITED (IN) | 2012-08-30 | — | — | WO | disclosed |
| US-20120035357-A1 | PROCESS FOR THE PREPARATION OF CARBAPENEM ANTIBIOTIC | ORCHID CHEMICALS & PHARMACEUTICALS LTD. (IN) | 2012-02-09 | — | — | US | disclosed |
| EP-2401278-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF CARBAPENEM ANTIBIOTIC | Orchid Chemicals&Pharmaceuticals Limited (IN) | 2012-01-04 | — | — | EP | disclosed |
| US-20110288289-A1 | Preparation of Carbapenem Intermediate and Their Use | SAVIOR LIFETEC CORPORATION (TW) | 2011-11-24 | — | — | US | disclosed |
| US-20110288290-A1 | PROCESS FOR THE PREPARATION OF CARBAPENEM USING CABAPENEM INTERMEDIATES AND RECOVERY OF CABAPENEM | SAVIOR LIFETEC CORPORATION (TW) | 2011-11-24 | — | — | US | disclosed |
| EP-2388261-A2 | Improved process for the preparation of carbapenem using carbapenem intermediates and recovery of carbapenem | Savior Lifetec Corporation (TW) | 2011-11-23 | — | — | EP | disclosed |
| US-D647009-S1 | Motor vehicle and/or toy replica thereof | TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) | 2011-10-18 | — | — | US | disclosed |
| WO-2010097686-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF CARBAPENEM ANTIBIOTIC | ORCHID CHEMICALS & PHARMACEUTICALS LTD (IN) | 2010-09-02 | — | — | WO | disclosed |
| EP-0528678-B1 | A pyrrolidylthiocarbapenem derivative with antibacterial activity | SHIONOGI & CO (JP) | 2001-05-23 | — | — | EP | disclosed |
| US-5703243-A | Intermediates for pyrrolidylthiocarbapenem derivative | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1997-12-30 | — | — | US | disclosed |
| US-5317016-A | Pyrrolidylthiocarbapenem derivative | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1994-05-31 | — | — | US | disclosed |
| EP-0528678-A1 | A pyrrolidylthiocarbapenem derivative | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1993-02-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120035357-A1 | PROCESS FOR THE PREPARATION OF CARBAPENEM ANTIBIOTIC | MGAM, PDHB, SI | CA12 1350/4885CA1 3995/4885CA2 2207/4885 |
| US-20110288289-A1 | Preparation of Carbapenem Intermediate and Their Use | SI, MGAM, IDE | CA12 2505/4885CA1 4566/4885CA2 4170/4885 |
| US-20110288290-A1 | PROCESS FOR THE PREPARATION OF CARBAPENEM USING CABAPENEM INTERMEDIATES AND RECOVERY OF CABAPENEM | MGAM, PMM2, PYGM | CA12 2285/4885CA1 4364/4885CA2 3453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.