SCHEMBL1970452

SCHEMBL1970452

N#CC1(C(=O)O)CCOCC1

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.37
DPP4 P27487 1/20 0.33
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10846854 0.98 LMNA (0.36) LMNADPP4ALDH1A1
SCHEMBL248308 0.83
Hydrochloric Acid SCHEMBL9422815 0.80
SCHEMBL21938458 0.80 LMNA (0.36) LMNADPP4
SCHEMBL12436912 0.80 LMNA (0.36) LMNADPP4ALDH1A1
SCHEMBL2087384 0.78 ALDH1A1 (0.40) ALDH1A1
SCHEMBL5551595 0.78
SCHEMBL10847408 0.77 TSHR (0.36) ALDH1A1
SCHEMBL24770416 0.77 LMNA (0.34) LMNADPP4ALDH1A1
SCHEMBL2275815 0.76 ALDH1A1 (0.44) LMNADPP4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080306287-A1 Process for Preparing Tetrahydropyran-4-Carboxylic Acid Compound UBE INDUSTRIES, LTD. (JP) 2008-12-11 US claimed
EP-4727938-A1 BICYCLIC HETEROAROMATIC COMPOUNDS FOR TREATING NEUROLOGICAL DISORDERS Prothena Biosciences Limited (IE) 2026-04-22 EP disclosed
EP-3858833-B9 AMINONORBORNANE DERIVATIVE AND MANUFACTURE METHOD THEREOF AND USE THEREOF TRANSTHERA SCIENCES NANJING INC (CN) 2026-03-11 EP disclosed
US-12473285-B2 DCN-1 modulating compounds and methods of use thereof CELLARITY, INC. (US) 2025-11-18 US disclosed
EP-3858833-B1 AMINONORBORNANE DERIVATIVE AND MANUFACTURE METHOD THEREOF AND USE THEREOF TRANSTHERA SCIENCES NANJING INC (CN) 2025-10-22 EP disclosed
US-12391679-B2 Benzamide-substituted bicyclic imidazo- and pyrazolo-fused -pyridine, -pyrimide, and -pyridazine compounds for treatment of inflammatory diseases ONCO3R THERAPEUTICS BV (BE) 2025-08-19 US disclosed
US-20250257063-A1 DCN-1 MODULATING COMPOUNDS AND METHODS OF USE THEREOF THAMES PHARMA PARTNERS 2025-08-14 US disclosed
US-20250163057-A1 DCN-1 MODULATING COMPOUNDS AND METHODS OF USE THEREOF THAMES PHARMA PARTNERS 2025-05-22 US disclosed
WO-2025096956-A1 DCN-1 MODULATING COMPOUNDS AND METHODS OF USE THEREOF CELLARITY, INC. (US) 2025-05-08 WO disclosed
US-12291534-B2 Aminonorbornane derivative and manufacture method therefor and use thereof TRANSTHERA SCIENCES (NANJING), INC. (CN) 2025-05-06 US disclosed
US-7300953-B2 Process for preparing nitrile compound, carboxylic acid compound or carboxylic acid ester compound UBE INDUSTRIES, LTD (JP) 2007-11-27 US disclosed
EP-1856110-A1 OXYINDOLE DERIVATIVES AS 5HT4 RECEPTOR AGONISTS Pfizer, Inc. (US) 2007-11-21 EP disclosed
CN-101061102-A Process for producing tetrahydropyran-4-carboxylic acid compound UBE INDUSTRIES (JP) 2007-10-24 CN disclosed
US-20070043107-A1 Processes for preparing alkyl 3-(4-tetrahydropyranyl)-3-oxopropanoate compound and 4-acyltetrahydropyrane UBE INDUSTRIES, LTD. (JP) 2007-02-22 US disclosed
US-20060287541-A1 Subjecting a 4-substituted tetrahydropyran-4-carboxylic acid compound to to decarboxylation in the presence of a metal catalyst for producing 4-substituted tetrahydropyran UBE INDUSTRIES, LTD. (JP) 2006-12-21 US disclosed
EP-1700852-A1 PROCESSES FOR PRODUCING ALKYL 3-(4-TETRAHYDROPYRANYL)-3-OXOPROPIONATE COMPOUND AND 4-ACYLTETRAHYDROPYRAN Ube Industries, Ltd. (JP) 2006-09-13 EP disclosed
US-20060194842-A1 Oxyindole derivatives PFIZER INC. 2006-08-31 US disclosed
WO-2006090279-A1 OXYINDOLE DERIVATIVES AS 5HT4 RECEPTOR AGONISTS PFIZER JAPAN INC. (JP) 2006-08-31 WO disclosed
EP-1671937-A1 METHOD FOR PRODUCING NITRILE COMPOUND, CARBOXYLIC ACID COMPOUND OR CARBOXYLATE COMPOUND Ube Industries, Ltd. (JP) 2006-06-21 EP disclosed
WO-2006054688-A1 PROCESS FOR PRODUCING TETRAHYDROPYRAN-4-CARBOXYLIC ACID COMPOUND UBE INDUSTRIES, LTD. (JP) 2006-05-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060287541-A1 Subjecting a 4-substituted tetrahydropyran-4-carboxylic acid compound to to decarboxylation in the presence of a metal catalyst for producing 4-substituted tetrahydropyran CBR1, ALDH18A1, ME1 LMNA 4534/4885DPP4 1881/4885ALDH1A1 39/4885
US-12473285-B2 DCN-1 modulating compounds and methods of use thereof DCUN1D1, DCUN1D2, DCUN1D4 LMNA 2115/4885DPP4 3868/4885ALDH1A1 822/4885
US-20080306287-A1 Process for Preparing Tetrahydropyran-4-Carboxylic Acid Compound ADH1A, ADH1C, HPD LMNA 4054/4885DPP4 951/4885ALDH1A1 29/4885
US-12291534-B2 Aminonorbornane derivative and manufacture method therefor and use thereof BTK, LCK, SYK LMNA 3192/4885DPP4 4466/4885ALDH1A1 3912/4885
US-20070043107-A1 Processes for preparing alkyl 3-(4-tetrahydropyranyl)-3-oxopropanoate compound and 4-acyltetrahydropyrane DHPS, OXER1, CYP4A11 LMNA 3899/4885DPP4 1140/4885ALDH1A1 312/4885
US-20060194842-A1 Oxyindole derivatives HTR4, HTR5A, HRH4 LMNA 4515/4885DPP4 295/4885ALDH1A1 2553/4885
US-20250163057-A1 DCN-1 MODULATING COMPOUNDS AND METHODS OF USE THEREOF DCUN1D1, DCUN1D2, DCUN1D4 LMNA 2115/4885DPP4 3868/4885ALDH1A1 822/4885
US-12391679-B2 Benzamide-substituted bicyclic imidazo- and pyrazolo-fused -pyridine, -pyrimide, and -pyridazine compounds for treatment of inflammatory diseases IL5, IL15, IL1A LMNA 1910/4885DPP4 1054/4885ALDH1A1 1043/4885
US-20250257063-A1 DCN-1 MODULATING COMPOUNDS AND METHODS OF USE THEREOF DCUN1D1, DCUN1D2, DCUN1D4 LMNA 2115/4885DPP4 3868/4885ALDH1A1 822/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.