Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3447567 | 0.92 | THRB (0.49) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL3092716 | 0.87 | ALDH1A1 (0.46) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL1972023 | 0.85 | TSHR (0.60) | TSHRTHRBPOLBAPEX1HTT | |
| Hydrochloric Acid SCHEMBL6114873 | 0.83 | TSHR (0.66) | TSHRTHRBPOLBAPEX1HTT | |
| Hydrogen Sulfide SCHEMBL27984120 | 0.82 | TSHR (0.81) | TSHRTHRBPOLBAPEX1HTT | |
| Acetic Acid SCHEMBL27968233 | 0.81 | TSHR (0.78) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL19066401 | 0.80 | TSHR (0.84) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL14893 | 0.80 | TSHR (0.84) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL11583525 | 0.80 | TSHR (0.84) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL452716 | 0.79 | ALDH1A1 (0.41) | TSHRTHRBAPEX1ALDH1A1CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11975093-B2 | Composition comprising oil and polyion complex including cellulose-based cationic polymer with at least one fatty chain | L'OREAL (FR) | 2024-05-07 | — | — | US | disclosed |
| US-11819564-B2 | Composition comprising polyion complex particle and oil | L'OREAL (FR) | 2023-11-21 | — | — | US | disclosed |
| WO-2021039936-A1 | COMPOSITION COMPRISING POLYION COMPLEX AND TEXTURE AGENT | L'OREAL (FR) | 2021-03-04 | — | — | WO | disclosed |
| US-20200330363-A1 | COMPOSITION COMPRISING OIL AND POLYION COMPLEX INCLUDING CELLULOSE-BASED CATIONIC POLYMER WITH AT LEAST ONE FATTY CHAIN | L'OREAL (FR) | 2020-10-22 | — | — | US | disclosed |
| US-20200163864-A1 | COMBINATION OF POLYION COMPLEX PARTICLE AND NON-POLYMERIC ACID OR BASE HAVING TWO OR MORE DISSOCIATION CONSTANTS | L'OREAL (FR) | 2020-05-28 | — | — | US | disclosed |
| US-20200163866-A1 | COMPOSITION COMPRISING POLYION COMPLEX PARTICLE AND OIL | L'OREAL (FR) | 2020-05-28 | — | — | US | disclosed |
| EP-2194957-B1 | COMPOSITION COMPRISING AT LEAST ONE AMMONIUM SALT, AQUEOUS AMMONIA AND AT LEAST ONE AMINO ACID | L'ORÉAL (FR) | 2017-06-14 | — | — | EP | disclosed |
| WO-2013069165-A1 | COSMETIC COMPOSITION FOR KERATIN FIBERS | L'OREAL (FR) | 2013-05-16 | — | — | WO | disclosed |
| US-7862803-B2 | Oxidizing composition for treating keratin materials based on amphiphilic polymers of at least one ethylenically unsaturated monomer with a sulphonic group and comprising a hydrophobic portion | L'OREAL (FR) | 2011-01-04 | — | — | US | disclosed |
| US-7771491-B2 | Oxidation dye composition for keratin fibers, comprising at least one oxidation dye, at least one associative polymer, at least one nonionic cellulose-based compound not comprising a C8-C30 fatty chain, and at least one cationic polymer with a charge density of greater than 1 meq/g and not comprising a C8-C30 fatty chain | L'OREAL S.A. (FR) | 2010-08-10 | — | — | US | disclosed |
| US-20040074015-A1 | Oxidising composition for treating keratinous materials based on amphiphilic polymers of at least an ethylenically unsaturated monomer containing a sulfonic group and comprising a hydrophobic part | L'OREAL (FR) | 2004-04-22 | — | — | US | disclosed |
| US-20040049860-A1 | Oxidation dyeing composition for keratinous fibres comprising glycerine and a polyol other than glycerine in a specific ratio | L'OREAL (FR) | 2004-03-18 | — | — | US | disclosed |
| US-20040049861-A1 | Oxidation dyeing composition for keratinous fibres comprising an associative polymer and a pearling agent | L'OREAL S.A. (FR) | 2004-03-18 | — | — | US | disclosed |
| US-20040001796-A9 | Cosmetic compositions containing a methacrylic acid copolymer, a dimethicone, a nacreous agent and a cationic polymer, and uses thereof | L'OREAL S.A. (FR) | 2004-01-01 | — | — | US | disclosed |
| US-20030152534-A1 | Composition for dyeing keratin fibers comprising a particular aminosilicone | L'OREAL S.A. (FR) | 2003-08-14 | — | — | US | disclosed |
| US-20030140429-A1 | Keratin fibre dyeing composition comprising a particular aminosilicone | L'OREAL S.A. (FR) | 2003-07-31 | — | — | US | disclosed |
| US-20030108503-A1 | Cosmetic compositions containing a methacrylic acid copolymer, a silicone and a cationic polymer, and uses thereof | L'OREAL S.A. (FR) | 2003-06-12 | — | — | US | disclosed |
| US-20030103927-A1 | Cosmetic compositions containing a methacrylic acid copolymer, a silicone and a cationic polymer, and uses thereof | L'OREAL S.A. (FR) | 2003-06-05 | — | — | US | disclosed |
| US-20030103926-A1 | Cosmetic compositions containing a methacrylic acid copolymer, a dimethicone, a nacreous agent and a cationic polymer, and uses thereof | MAUBRU MIREILLE (FR) | 2003-06-05 | — | — | US | disclosed |
| US-20030103929-A1 | Cosmetic compositions containing a methacrylic acid copolymer, a silicone and a cationic polymer, and uses thereof | L'OREAL S.A. (FR) | 2003-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (15 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200330363-A1 | COMPOSITION COMPRISING OIL AND POLYION COMPLEX INCLUDING CELLULOSE-BASED CATIONIC POLYMER WITH AT LEAST ONE FATTY CHAIN | PRKCA, PRKCH, CUTA | TSHR 4639/4885THRB 3971/4885POLB 799/4885 |
| US-20030103927-A1 | Cosmetic compositions containing a methacrylic acid copolymer, a silicone and a cationic polymer, and uses thereof | KRT18, CUTA, MARK1 | TSHR 3152/4885THRB 2828/4885POLB 2779/4885 |
| US-20030103929-A1 | Cosmetic compositions containing a methacrylic acid copolymer, a silicone and a cationic polymer, and uses thereof | CUTA, KRT18, MUC1 | TSHR 3507/4885THRB 3113/4885POLB 2215/4885 |
| US-11975093-B2 | Composition comprising oil and polyion complex including cellulose-based cationic polymer with at least one fatty chain | PRKCA, PRKCH, CUTA | TSHR 4639/4885THRB 3971/4885POLB 799/4885 |
| US-20040001796-A9 | Cosmetic compositions containing a methacrylic acid copolymer, a dimethicone, a nacreous agent and a cationic polymer, and uses thereof | KRT18, CUTA, MUC1 | TSHR 3212/4885THRB 3636/4885POLB 2289/4885 |
| US-20030152534-A1 | Composition for dyeing keratin fibers comprising a particular aminosilicone | KRT18, TUBB8, TUBA8 | TSHR 4575/4885THRB 3408/4885POLB 1700/4885 |
| US-20030108503-A1 | Cosmetic compositions containing a methacrylic acid copolymer, a silicone and a cationic polymer, and uses thereof | KRT18, CUTA, ACR | TSHR 3215/4885THRB 3104/4885POLB 3036/4885 |
| US-20200163866-A1 | COMPOSITION COMPRISING POLYION COMPLEX PARTICLE AND OIL | PIK3CA, PTEN, PIK3CG | TSHR 3897/4885THRB 3892/4885POLB 336/4885 |
| US-20030140429-A1 | Keratin fibre dyeing composition comprising a particular aminosilicone | KRT18, TUBB3, TUBA3E | TSHR 4749/4885THRB 4315/4885POLB 1933/4885 |
| US-20030103926-A1 | Cosmetic compositions containing a methacrylic acid copolymer, a dimethicone, a nacreous agent and a cationic polymer, and uses thereof | KRT18, CUTA, MUC1 | TSHR 3212/4885THRB 3636/4885POLB 2289/4885 |
| US-20040049861-A1 | Oxidation dyeing composition for keratinous fibres comprising an associative polymer and a pearling agent | KRT18, COXFA4L2, TUBB4A | TSHR 4095/4885THRB 2705/4885POLB 542/4885 |
| US-20040049860-A1 | Oxidation dyeing composition for keratinous fibres comprising glycerine and a polyol other than glycerine in a specific ratio | KRT18, AKR1B10, ACAD10 | TSHR 4538/4885THRB 2802/4885POLB 320/4885 |
| US-11819564-B2 | Composition comprising polyion complex particle and oil | PIK3CA, PTEN, PIK3CG | TSHR 3897/4885THRB 3892/4885POLB 336/4885 |
| US-20200163864-A1 | COMBINATION OF POLYION COMPLEX PARTICLE AND NON-POLYMERIC ACID OR BASE HAVING TWO OR MORE DISSOCIATION CONSTANTS | PRKCA, PRKCI, PRKCG | TSHR 2767/4885THRB 3412/4885POLB 424/4885 |
| US-20040074015-A1 | Oxidising composition for treating keratinous materials based on amphiphilic polymers of at least an ethylenically unsaturated monomer containing a sulfonic group and comprising a hydrophobic part | KRT18, DSG1, CUTA | TSHR 4775/4885THRB 4760/4885POLB 2096/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.