Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | ADH1B | P00325 | 1/20 | 0.35 |
| ▸ | ADH1C | P00326 | 1/20 | 0.35 |
| ▸ | ADH1A | P07327 | 1/20 | 0.35 |
| ▸ | ADH7 | P40394 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5367349 | 0.97 | LMNA (0.48) | LMNACNR1ADRA1ATDP1KDM4E | |
| Hydrochloric Acid SCHEMBL22575418 | 0.94 | ABCC3 (0.50) | LMNACNR1ADRA1ATDP1KDM4E | |
| Hydrazine SCHEMBL28481730 | 0.92 | LMNA (0.44) | LMNACNR1ADRA1ATDP1KDM4E | |
| Ammonia Solution, Strong SCHEMBL198005 | 0.90 | EPHX1 (0.46) | LMNACNR1ADRA1ATDP1KDM4E | |
| Ammonia Solution, Strong SCHEMBL197373 | 0.90 | EPHX1 (0.46) | LMNACNR1ADRA1ATDP1KDM4E | |
| SCHEMBL7775237 | 0.89 | TSHR (0.48) | LMNACNR1ADRA1ATDP1KDM4E | |
| SCHEMBL25132260 | 0.86 | EPHX1 (0.48) | LMNACNR1ADRA1ATDP1KDM4E | |
| SCHEMBL7776968 | 0.86 | EPHX1 (0.48) | LMNACNR1ADRA1ATDP1KDM4E | |
| Hydrochloric Acid SCHEMBL22575318 | 0.86 | ABCC3 (0.48) | LMNACNR1ADRA1ATDP1KDM4E | |
| SCHEMBL20033727 | 0.86 | EPHX1 (0.48) | LMNACNR1ADRA1ATDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118480173-A | Cationic polyester and preparation method and application thereof | 深圳市信必递生物科技有限公司 | 2024-08-13 | — | — | CN | disclosed |
| EP-3642253-B1 | BLOCKING AGENTS FOR AMINES, LATENT CURING AGENTS AND POLYURETHANE COMPOSITIONS | SIKA TECH AG (CH) | 2023-05-10 | — | — | EP | disclosed |
| US-11518736-B2 | Blocking agent for amines, latent hardeners and polyurethane compositions | SIKA TECHNOLOGY AG (CH) | 2022-12-06 | — | — | US | disclosed |
| CN-115368824-A | Fast curing migration-free compositions based on organic polymers containing silane groups | SIKA技术股份公司 | 2022-11-22 | — | — | CN | disclosed |
| EP-3394132-B1 | TWO-COMPONENT POLYURETHANE COMPOSITION | SIKA TECH AG (CH) | 2022-11-09 | — | — | EP | disclosed |
| EP-3394139-B1 | POLYURETHANE COMPOSITION WITH LOW PLASTICIZER MIGRATION | SIKA TECH AG (CH) | 2022-07-20 | — | — | EP | disclosed |
| US-20220144746-A1 | PROCESS FOR PRODUCING 2,2-DIALKYL-3-ACYLOXYPROPANALS | SIKA TECHNOLOGY AG (CH) | 2022-05-12 | — | — | US | disclosed |
| CN-110753711-B | Amine blocking agent, latent curing agent and polyurethane composition | SIKA技术股份公司 | 2022-04-05 | — | — | CN | disclosed |
| EP-3969435-A1 | PROCESS FOR PRODUCING 2,2-DIALKYL-3-ACYLOXYPROPANALS | Sika Technology AG (CH) | 2022-03-23 | — | — | EP | disclosed |
| CN-108368233-B | Two-component polyurethane composition | SIKA技术股份公司 | 2022-02-08 | — | — | CN | disclosed |
| US-20100130674-A1 | METHOD FOR THE PRODUCTION OF POLYURETHANE COMPOSITIONS WITH A LOW ISOCYANATE MONOMER CONTENT | SIKA TECHNOLOGY AG (CH) | 2010-05-27 | — | — | US | disclosed |
| US-20100101455-A1 | ALDIMINES AND COMPOSITIONS COMPRISING ALDIMINE | SIKA TECHNOLOGY AG (CH) | 2010-04-29 | — | — | US | disclosed |
| US-20100006221-A1 | Amorphous polyurethane polymer and its use in hotmelt adhesives | SIKA TECHNOLOGY AG (CH) | 2010-01-14 | — | — | US | disclosed |
| US-20100003526-A1 | Polyurethane composition with good initial strength | SIKA TECHNOLOGY AG (CH) | 2010-01-07 | — | — | US | disclosed |
| US-7629433-B2 | Odor-less during hydrolytic deblocking, separation; for use as source for aldehydes; crosslinking agents | SIKA TECHNOLOGY AG (CH) | 2009-12-08 | — | — | US | disclosed |
| US-20090176944-A1 | Aldimines Comprising Reactive Groups Containing Active Hydrogen, and Use Thereof | SIKA TECHNOLOGY AG (CH) | 2009-07-09 | — | — | US | disclosed |
| US-20090159204-A1 | Moisture-Hardened Polyurethane Compositions Containing Compounds Comprising Aldimine | SIKA TECHNOLOGY AG | 2009-06-25 | — | — | US | disclosed |
| US-20090099333-A1 | Compounds Containing Aldimine | SIKA TECHNOLOGY AG (CH) | 2009-04-16 | — | — | US | disclosed |
| US-20080280145-A1 | moisture-reactive hot-melt adhesive which comprises at least one aldimine and at least one polyurethane polymer ( polyesterurethane copolymer, polyetherurethane copolymer)which contains isocyanate groups and is solid at room temperature; bonded assembly is notable for improved adhesive | SIKA TECHNOLOGY AG (CH) | 2008-11-13 | — | — | US | disclosed |
| US-20080251204-A1 | Reactive Polyurethane-Hot Melt Adhesive Having a Low Isocyanate-Monomer Content | SIKA TECHNOLOGY AG (CH) | 2008-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11518736-B2 | Blocking agent for amines, latent hardeners and polyurethane compositions | ODC1, KDM2B, ALKBH2 | LMNA 1024/4885CNR1 2867/4885ADRA1A 850/4885 |
| US-20100101455-A1 | ALDIMINES AND COMPOSITIONS COMPRISING ALDIMINE | ALDH7A1, ILK, ALDH3A1 | LMNA 404/4885CNR1 4806/4885ADRA1A 2896/4885 |
| US-20090176944-A1 | Aldimines Comprising Reactive Groups Containing Active Hydrogen, and Use Thereof | ADH5, ADH1C, ADH1A | LMNA 2995/4885CNR1 3485/4885ADRA1A 562/4885 |
| US-20220144746-A1 | PROCESS FOR PRODUCING 2,2-DIALKYL-3-ACYLOXYPROPANALS | ADCY4, ADCY1, ADCY2 | LMNA 1370/4885CNR1 2378/4885ADRA1A 294/4885 |
| US-20090099333-A1 | Compounds Containing Aldimine | ALDH7A1, ALDH3A1, ALDH1A1 | LMNA 2415/4885CNR1 2903/4885ADRA1A 1771/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.