Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PLA2G2A | P14555 | 4/20 | 0.41 |
| ▸ | PLA2G10 | O15496 | 3/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL21646049 | 0.98 | CYP3A4 (0.48) | CYP3A4ALDH1A1TSHRTDP1PLA2G2A | |
| SCHEMBL28681774 | 0.82 | PLA2G2A (0.57) | CYP3A4ALDH1A1TSHRTDP1PLA2G2A | |
| SCHEMBL4952428 | 0.79 | ALDH1A1 (0.50) | CYP3A4ALDH1A1TSHRTDP1PLA2G2A | |
| SCHEMBL4949010 | 0.76 | ALDH1A1 (0.62) | CYP3A4ALDH1A1TSHRTDP1PLA2G2A | |
| SCHEMBL19439093 | 0.76 | TSHR (0.53) | CYP3A4ALDH1A1TSHRTDP1PLA2G2A | |
| SCHEMBL30073173 | 0.73 | HDAC1 (0.42) | ALDH1A1TSHRTDP1GFERCA12 | |
| SCHEMBL28778955 | 0.73 | PLA2G2A (0.47) | ALDH1A1PLA2G2APLA2G10SLCO1B1 | |
| SCHEMBL5550889 | 0.73 | PLA2G2A (0.47) | ALDH1A1PLA2G2APLA2G10SLCO1B1 | |
| SCHEMBL28974830 | 0.72 | MAPT (0.40) | ALDH1A1TDP1RPS6KB1PARP10 | |
| SCHEMBL30824614 | 0.70 | DGAT1 (0.41) | ALDH1A1TSHRTDP1PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2516503-B1 | ANTIMICROBIAL POLYMERS AND METHODS OF MANUFACTURE THEREOF | IBM (US) | 2016-07-20 | — | — | EP | disclosed |
| US-9284404-B2 | Antimicrobial polymers and methods of manufacture thereof | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2016-03-15 | — | — | US | disclosed |
| US-9084735-B2 | Self-assembling bis-urea compounds for drug delivery | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2015-07-21 | — | — | US | disclosed |
| US-20150037390-A1 | SELF-ASSEMBLING BIS-UREA COMPOUNDS FOR DRUG DELIVERY | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2015-02-05 | — | — | US | disclosed |
| US-8921426-B2 | Cationic bis-urea compounds as effective antimicrobial agents | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2014-12-30 | — | — | US | disclosed |
| US-20130281515-A1 | CATIONIC BIS-UREA COMPOUNDS AS EFFECTIVE ANTIMICROBIAL AGENTS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2013-10-24 | — | — | US | disclosed |
| US-8361495-B2 | Antimicrobial polymers and methods of manufacture thereof | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2013-01-29 | — | — | US | disclosed |
| US-20130011457-A1 | ANTIMICROBIAL POLYMERS AND METHODS OF MANUFACTURE THEREOF | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2013-01-10 | — | — | US | disclosed |
| EP-2516503-A1 | ANTIMICROBIAL POLYMERS AND METHODS OF MANUFACTURE THEREOF | International Business Machines Corporation (US) | 2012-10-31 | — | — | EP | disclosed |
| WO-2011078804-A1 | ANTIMICROBIAL POLYMERS AND METHODS OF MANUFACTURE THEREOF | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2011-06-30 | — | — | WO | disclosed |
| US-20110150977-A1 | ANTIMICROBIAL POLYMERS AND METHODS OF MANUFACTURE THEREOF | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130011457-A1 | ANTIMICROBIAL POLYMERS AND METHODS OF MANUFACTURE THEREOF | MLEC, NOD2, PAM | CYP3A4 4614/4885ALDH1A1 3648/4885TSHR 4155/4885 |
| US-20130281515-A1 | CATIONIC BIS-UREA COMPOUNDS AS EFFECTIVE ANTIMICROBIAL AGENTS | NOS3, NOS1, NOS2 | CYP3A4 1443/4885ALDH1A1 4147/4885TSHR 2518/4885 |
| US-20150037390-A1 | SELF-ASSEMBLING BIS-UREA COMPOUNDS FOR DRUG DELIVERY | SLC14A1, NONO, PUF60 | CYP3A4 1581/4885ALDH1A1 4051/4885TSHR 4559/4885 |
| US-20110150977-A1 | ANTIMICROBIAL POLYMERS AND METHODS OF MANUFACTURE THEREOF | MLEC, NOD2, PAM | CYP3A4 4614/4885ALDH1A1 3648/4885TSHR 4155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.