Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1022463 | 0.67 | — | — | |
| SCHEMBL28330102 | 0.67 | — | — | |
| SCHEMBL3139453 | 0.67 | — | — | |
| Phosphoric Acid SCHEMBL27997783 | 0.66 | LMNA (0.35) | LMNABLMPMP22CYP2C9TSHR | |
| Phosphoric Acid Monomethyl Ester SCHEMBL4399195 | 0.66 | — | — | |
| Phosphoric Acid Monomethyl Ester SCHEMBL26929140 | 0.65 | ALDH1A1 (0.36) | LMNA | |
| SCHEMBL27829275 | 0.65 | CA2 (0.39) | — | |
| Methyl Phosphonate SCHEMBL1820657 | 0.65 | — | — | |
| SCHEMBL2904505 | 0.65 | — | — | |
| Phosphoric Acid Monomethyl Ester SCHEMBL11053560 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11547639-B2 | Dental composition containing platinum nanoparticles | KURARAY NORITAKE DENTAL INC. (JP) | 2023-01-10 | — | — | US | disclosed |
| EP-3388046-B1 | DENTAL ADHESIVE | KURARAY NORITAKE DENTAL INC (JP) | 2020-06-10 | — | — | EP | disclosed |
| US-10456333-B2 | Dental adhesive | KURARAY NORITAKE DENTAL INC. (JP) | 2019-10-29 | — | — | US | disclosed |
| US-20180360696-A1 | DENTAL ADHESIVE | KURARAY NORITAKE DENTAL INC. (JP) | 2018-12-20 | — | — | US | disclosed |
| EP-3388046-A1 | DENTAL ADHESIVE | Kuraray Noritake Dental Inc. (JP) | 2018-10-17 | — | — | EP | disclosed |
| US-10071028-B2 | Dental adhesive | KURARAY NORITAKE DENTAL INC. (JP) | 2018-09-11 | — | — | US | disclosed |
| EP-3056188-B1 | DENTAL ADHESIVE KIT | KURARAY NORITAKE DENTAL INC (JP) | 2018-08-08 | — | — | EP | disclosed |
| US-9789031-B2 | Dental adhesive kit | KURARAY NORITAKE DENTAL INC. (JP) | 2017-10-17 | — | — | US | disclosed |
| US-20170196778-A1 | DENTAL ADHESIVE | KURARAY NORITAKE DENTAL INC. (JP) | 2017-07-13 | — | — | US | disclosed |
| EP-3156033-A1 | DENTAL ADHESIVE | Kuraray Noritake Dental Inc. (JP) | 2017-04-19 | — | — | EP | disclosed |
| US-20160235631-A1 | DENTAL ADHESIVE KIT | KURARAY NORITAKE DENTAL INC. (JP) | 2016-08-18 | — | — | US | disclosed |
| EP-3056188-A1 | DENTAL ADHESIVE KIT | Kuraray Noritake Dental Inc. (JP) | 2016-08-17 | — | — | EP | disclosed |
| US-8148571-B2 | Compound, composition comprising the same, and process for production of polymerizable amide | KURARAY MEDICAL INC. (JP) | 2012-04-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170196778-A1 | DENTAL ADHESIVE | ADGRF1, ADGRE5, NR1I3 | LMNA 4368/4885BLM 3736/4885PMP22 4428/4885 |
| US-20160235631-A1 | DENTAL ADHESIVE KIT | CDH1, AAK1, BRSK1 | LMNA 2183/4885BLM 2331/4885PMP22 4602/4885 |
| US-10071028-B2 | Dental adhesive | ADGRF1, ADGRE5, NR1I3 | LMNA 4368/4885BLM 3736/4885PMP22 4428/4885 |
| US-20180360696-A1 | DENTAL ADHESIVE | PTK2, CDH1, CAD | LMNA 4463/4885BLM 3409/4885PMP22 3515/4885 |
| US-10456333-B2 | Dental adhesive | PTK2, CDH1, CAD | LMNA 4463/4885BLM 3409/4885PMP22 3515/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.