Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | NOS2 | P35228 | 2/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7515864 | 0.72 | ALDH1A1 (0.39) | ALDH1A1NOS1NOS2NOS3 | |
| SCHEMBL8717953 | 0.69 | ALDH1A1 (0.30) | ALDH1A1NOS1NOS2NOS3 | |
| SCHEMBL4064825 | 0.68 | ALDH1A1 (0.35) | ALDH1A1NOS1NOS2NOS3 | |
| SCHEMBL895510 | 0.68 | CA1 (0.42) | ALDH1A1NOS1NOS2NOS3 | |
| SCHEMBL6593076 | 0.68 | ALDH1A1 (0.35) | ALDH1A1NOS1NOS2NOS3 | |
| SCHEMBL120444 | 0.68 | CA1 (0.42) | ALDH1A1NOS1NOS2NOS3 | |
| SCHEMBL12333841 | 0.68 | CA1 (0.42) | ALDH1A1NOS1NOS2NOS3 | |
| SCHEMBL10476883 | 0.68 | ALDH1A1 (0.35) | ALDH1A1NOS1NOS2NOS3 | |
| SCHEMBL22397285 | 0.68 | CA1 (0.42) | ALDH1A1NOS1NOS2NOS3 | |
| SCHEMBL19733321 | 0.68 | ALDH1A1 (0.35) | ALDH1A1NOS1NOS2NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 233 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240240226-A1 | FLUOROGENIC ASSAY FOR RAPID SCREENING OF BACTERIAL BETA-LACTAMASE ACTIVITY | UNIV LELAND STANFORD JUNIOR (US) | 2024-07-18 | — | — | US | disclosed |
| EP-4185293-A1 | COMPOSITIONS AND METHODS FOR ACTIVATING PYRUVATE KINASE | The Regents of The University of Michigan (US) | 2023-05-31 | — | — | EP | disclosed |
| WO-2023081261-A1 | TUNABLE FLUORESCENT COMPOUNDS AND USES THEREOF | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2023-05-11 | — | — | WO | disclosed |
| US-20210196716-A1 | COMPOSITIONS AND METHODS FOR TREATING EYE DISORDERS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2021-07-01 | — | — | US | disclosed |
| EP-3697354-A1 | COMPOSITIONS AND METHODS FOR TREATING EYE DISORDERS | The Regents of The University of Michigan (US) | 2020-08-26 | — | — | EP | disclosed |
| US-10675364-B2 | Rhodol fluorophores for near-infrared imaging | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2020-06-09 | — | — | US | disclosed |
| US-10570150-B2 | 6,7-trans cephalosporin-based probes for detecting bacteria expressing a metallo-beta-lactamase | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2020-02-25 | — | — | US | disclosed |
| US-10441588-B2 | Methods and compositions for treating bacterial infection | CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 2019-10-15 | — | — | US | disclosed |
| EP-2844258-B1 | METHODS AND COMPOSITIONS FOR TREATING BACTERIAL INFECTION | UNIV MICHIGAN REGENTS (US) | 2019-09-11 | — | — | EP | disclosed |
| EP-2063894-B1 | FORMULATIONS CONTAINING PYRIDAZINE COMPOUNDS FOR TREATING NEUROINFLAMMATORY DISEASES | UNIV NORTHWESTERN (US) | 2019-08-28 | — | — | EP | disclosed |
| US-20050113460-A1 | Compositions and methods relating to novel compounds and targets thereof | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2005-05-26 | — | — | US | disclosed |
| WO-2005034943-A1 | INDOLE ANTIVIRAL COMPOSITIONS AND METHODS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2005-04-21 | — | — | WO | disclosed |
| US-20050026910-A1 | Benzimidazole derivatives for use as therapeutic agents to treat a number of conditions associated with retroviral infection; HIV-1 treatment | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2005-02-03 | — | — | US | disclosed |
| WO-2005004988-A2 | COMPOSITIONS AND METHODS RELATING TO NOVEL COMPOUNDS AND TARGETS THEREOF | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2005-01-20 | — | — | WO | disclosed |
| US-20040241781-A1 | Compositions and methods relating to novel compounds and targets thereof | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2004-12-02 | — | — | US | disclosed |
| US-20040220180-A1 | Compositions relating to novel compounds and targets thereof | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2004-11-04 | — | — | US | disclosed |
| US-20040176358-A1 | Compositions and methods relating to novel compounds and targets thereof | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2004-09-09 | — | — | US | disclosed |
| EP-1423122-A2 | COMPOSITIONS AND METHODS RELATING TO NOVEL BENZODIAZEPINE COMPOUNDS AND TARGETS THEREOF | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2004-06-02 | — | — | EP | disclosed |
| US-20030119029-A1 | Compositions and methods relating to novel benzodiazepine compounds and targets thereof | REGENTS OF THE UNIVERSITY OF MICHIGAN | 2003-06-26 | — | — | US | disclosed |
| WO-2003015703-A2 | COMPOSITIONS AND METHODS RELATING TO NOVEL BENZODIAZEPINE COMPOUNDS AND TARGETS THEREOF | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2003-02-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10570150-B2 | 6,7-trans cephalosporin-based probes for detecting bacteria expressing a metallo-beta-lactamase | CMBL, MGAM, GUSB | ALDH1A1 1338/4885NOS1 3979/4885NOS2 4207/4885 |
| US-20050026910-A1 | Benzimidazole derivatives for use as therapeutic agents to treat a number of conditions associated with retroviral infection; HIV-1 treatment | ABAT, MAVS, ZC3HAV1 | ALDH1A1 162/4885NOS1 2525/4885NOS2 2506/4885 |
| US-20050113460-A1 | Compositions and methods relating to novel compounds and targets thereof | BAX, BAD, GABRB3 | ALDH1A1 2634/4885NOS1 1897/4885NOS2 1603/4885 |
| US-10441588-B2 | Methods and compositions for treating bacterial infection | MMP8, CUTA, ELANE | ALDH1A1 2604/4885NOS1 430/4885NOS2 225/4885 |
| US-20030119029-A1 | Compositions and methods relating to novel benzodiazepine compounds and targets thereof | GABRB1, GABRB3, GABRB2 | ALDH1A1 2307/4885NOS1 2343/4885NOS2 2095/4885 |
| US-20210196716-A1 | COMPOSITIONS AND METHODS FOR TREATING EYE DISORDERS | CRYAB, PDE6C, PDE6D | ALDH1A1 1761/4885NOS1 1513/4885NOS2 1315/4885 |
| US-20040220180-A1 | Compositions relating to novel compounds and targets thereof | BAX, BAD, GABRB1 | ALDH1A1 2873/4885NOS1 2228/4885NOS2 1963/4885 |
| US-20040241781-A1 | Compositions and methods relating to novel compounds and targets thereof | BAX, BAD, GABRB3 | ALDH1A1 2634/4885NOS1 1897/4885NOS2 1603/4885 |
| US-20040176358-A1 | Compositions and methods relating to novel compounds and targets thereof | BAX, BAD, GABRB3 | ALDH1A1 2634/4885NOS1 1897/4885NOS2 1603/4885 |
| US-20240240226-A1 | FLUOROGENIC ASSAY FOR RAPID SCREENING OF BACTERIAL BETA-LACTAMASE ACTIVITY | CDA, CMBL, CTSF | ALDH1A1 203/4885NOS1 1622/4885NOS2 1793/4885 |
| US-10675364-B2 | Rhodol fluorophores for near-infrared imaging | ALDH1A2, DNER, DBNL | ALDH1A1 14/4885NOS1 216/4885NOS2 154/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.