SCHEMBL2139503

SCHEMBL2139503

Cc1cccc(-c2nc3ccccc3s2)c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 9/20 0.67
SMN1; SMN2 Q16637 6/20 0.67
MAPT P10636 6/20 0.67
KDM4E B2RXH2 6/20 0.67
NPC1 O15118 6/20 0.67
NFKB1 P19838 3/20 0.67
NFKB2 Q00653 3/20 0.67
RELA Q04206 3/20 0.67
ALDH1A1 P00352 3/20 0.67
MEN1 O00255 3/20 0.67
KMT2A Q03164 3/20 0.67
LMNA P02545 2/20 0.67
TP53 P04637 1/20 0.67
POLB P06746 1/20 0.67
HSD17B10 Q99714 1/20 0.67
TDP1 Q9NUW8 2/20 0.66
GAA P10253 3/20 0.58
L3MBTL1 Q9Y468 2/20 0.56
HPGD P15428 1/20 0.56
APP P05067 4/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16141213 0.97 RAB9A (0.63) RAB9ASMN1; SMN2MAPTKDM4ENPC1
Diacetamide SCHEMBL7105201 0.88 SMN1; SMN2 (0.67) RAB9ASMN1; SMN2MAPTKDM4ENPC1
SCHEMBL5461064 0.88 RAB9A (0.77) RAB9ASMN1; SMN2MAPTKDM4ENPC1
SCHEMBL14111242 0.87 MAPT (0.65) RAB9ASMN1; SMN2MAPTKDM4ENPC1
SCHEMBL15786286 0.86 KDM4E (0.64) RAB9ASMN1; SMN2MAPTKDM4ENPC1
SCHEMBL17059020 0.86 KDM4E (0.64) RAB9ASMN1; SMN2MAPTKDM4ENPC1
SCHEMBL6258552 0.85 KDM4E (0.51) RAB9ASMN1; SMN2MAPTKDM4ENPC1
SCHEMBL23594316 0.85 RAB9A (0.57) RAB9ASMN1; SMN2MAPTKDM4ENPC1
SCHEMBL12376182 0.84 RAB9A (0.73) RAB9ASMN1; SMN2MAPTKDM4ENPC1
SCHEMBL14506051 0.84 RAB9A (0.59) RAB9ASMN1; SMN2MAPTKDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11718606-B2 Polycyclic compound and organic light emitting element comprising same LG CHEM, LTD. (KR) 2023-08-08 US disclosed
US-11569453-B2 Polycyclic compound and organic light emitting element comprising same LG CHEM, LTD. (KR) 2023-01-31 US disclosed
US-11530201-B2 Triazine compounds substituted with bulky groups NOVALED GMBH (DE) 2022-12-20 US disclosed
CN-108250157-B Method for synthesizing N- [2- (2-arylbenzothiazole) ] -amide under catalysis of rhodium 江西师范大学 2021-12-21 CN disclosed
CN-110156716-B Synthetic method of benzothiazole ester derivative 安徽师范大学 2021-08-27 CN disclosed
US-20210020848-A1 POLYCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2021-01-21 US disclosed
EP-3763707-A1 AMINE DERIVATIVE AND AN ORGANIC ELECTROLUMINESCENT DEVICE THEREOF Changchun Hyperions Scientific Co., Ltd (CN) 2021-01-13 EP disclosed
US-20200361916-A1 Triazine Compounds substituted with Bulky Groups SAMSUNG SDI CO. LTD. (KR) 2020-11-19 US disclosed
US-10822330-B2 Heterocyclic compound and organic light emitting diode containing same LG CHEM, LTD. (KR) 2020-11-03 US disclosed
US-10800969-B2 Heterocyclic compound and organic light emitting element comprising same LG CHEM, LTD. (KR) 2020-10-13 US disclosed
US-8242278-B2 Process for producing biaryl compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-08-14 US disclosed
US-20120101278-A1 PROCESS FOR PRODUCING BIARYL COMPOUND HAGIYA KOJI (JP) 2012-04-26 US disclosed
US-20100071769-A1 FLUORENE DERIVATIVES AND ORGANIC ELECTRONIC DEVICE USING THE SAME LG CHEM, LTD. (KR) 2010-03-25 US disclosed
US-20100071769-A1 FLUORENE DERIVATIVES AND ORGANIC ELECTRONIC DEVICE USING THE SAME LG CHEM, LTD. (KR) 2010-03-25 US disclosed
EP-1473286-B1 PROCESS FOR PRODUCING BIARYL COMPOUND SUMITOMO CHEMICAL CO (JP) 2009-11-04 EP disclosed
US-20090216017-A1 PROCESS FOR PRODUCING BIARYL COMPOUND HAGIYA KOJI 2009-08-27 US disclosed
US-7554000-B2 Process for producing biaryl compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-06-30 US disclosed
WO-2008069586-A1 NEW FLUORENE DERIVATIVES AND ORGANIC ELECTRONIC DEVICE USING THE SAME LG CHEM, LTD. (KR) 2008-06-12 WO disclosed
US-20050096471-A1 Process for producing biaryl compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-05-05 US disclosed
EP-1473286-A1 PROCESS FOR PRODUCING BIARYL COMPOUND Sumitomo Chemical Company, Limited (JP) 2004-11-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120101278-A1 PROCESS FOR PRODUCING BIARYL COMPOUND PPOX, CAT, TYR RAB9A 2254/4885SMN1; SMN2 4152/4885MAPT 3403/4885
US-11530201-B2 Triazine compounds substituted with bulky groups POU5F1, POU2F1, IKZF2 RAB9A 4551/4885SMN1; SMN2 3804/4885MAPT 3013/4885
US-10800969-B2 Heterocyclic compound and organic light emitting element comprising same CRY1, CRY2, PER2 RAB9A 2886/4885SMN1; SMN2 3949/4885MAPT 1231/4885
US-20200361916-A1 Triazine Compounds substituted with Bulky Groups POU5F1, POU2F1, IKZF2 RAB9A 4551/4885SMN1; SMN2 3804/4885MAPT 3013/4885
US-11718606-B2 Polycyclic compound and organic light emitting element comprising same CRY1, CRY2, CYP1A1 RAB9A 3043/4885SMN1; SMN2 4272/4885MAPT 1909/4885
US-20090216017-A1 PROCESS FOR PRODUCING BIARYL COMPOUND PPOX, CAT, TYR RAB9A 2254/4885SMN1; SMN2 4152/4885MAPT 3403/4885
US-20100071769-A1 FLUORENE DERIVATIVES AND ORGANIC ELECTRONIC DEVICE USING THE SAME VDAC2, VDAC1, FTO RAB9A 766/4885SMN1; SMN2 722/4885MAPT 2483/4885
US-20210020848-A1 POLYCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME PPOX, NFE2L2, OGFOD1 RAB9A 4703/4885SMN1; SMN2 4116/4885MAPT 1709/4885
US-10822330-B2 Heterocyclic compound and organic light emitting diode containing same CRY1, CRY2, PER2 RAB9A 3102/4885SMN1; SMN2 4371/4885MAPT 1466/4885
US-20050096471-A1 Process for producing biaryl compound PPOX, CAT, TYR RAB9A 2254/4885SMN1; SMN2 4152/4885MAPT 3403/4885
US-11569453-B2 Polycyclic compound and organic light emitting element comprising same PPOX, NFE2L2, OGFOD1 RAB9A 4703/4885SMN1; SMN2 4116/4885MAPT 1709/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.