Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium Ion SCHEMBL17438932 | 0.97 | THRB (0.38) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL2742237 | 0.85 | THRB (0.40) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL2742244 | 0.80 | THRB (0.36) | THRBTSHR | |
| SCHEMBL4476422 | 0.76 | THRB (0.36) | THRBTSHR | |
| SCHEMBL14129207 | 0.73 | THRB (0.42) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL18530923 | 0.72 | THRB (0.39) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL8473833 | 0.72 | THRB (0.52) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL543948 | 0.72 | TSHR (0.39) | THRBTSHRALDH1A1 | |
| SCHEMBL27701673 | 0.72 | THRB (0.47) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL29091115 | 0.71 | TSHR (0.53) | THRBTSHRALDH1A1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230013430-A1 | SULFONIUM SALT, ACID GENERATOR, RESIST COMPOSITION, AND METHOD FOR PRODUCING DEVICE | TOYO GOSEI CO., LTD. (JP) | 2023-01-19 | — | — | US | disclosed |
| CN-109843853-B | Composition and method for manufacturing device using the same | 东洋合成工业株式会社 | 2022-09-20 | — | — | CN | disclosed |
| US-11142495-B2 | Composition and method for manufacturing device using same | TOYO GOSEI CO., LTD. (JP) | 2021-10-12 | — | — | US | disclosed |
| WO-2021095356-A1 | SULFONIUM SALT, ACID GENERATOR, RESIST COMPOSITION, AND METHOD FOR PRODUCING DEVICE | 東洋合成工業株式会社 | 2021-05-20 | — | — | WO | disclosed |
| US-20200048191-A1 | COMPOSITION AND METHOD FOR MANUFACTURING DEVICE USING SAME | TOYO GOSEI CO., LTD. (JP) | 2020-02-13 | — | — | US | disclosed |
| CN-109843853-A | The manufacturing method of composition and the equipment using the composition | 东洋合成工业株式会社 | 2019-06-04 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230013430-A1 | SULFONIUM SALT, ACID GENERATOR, RESIST COMPOSITION, AND METHOD FOR PRODUCING DEVICE | ARSA, SULT1A1, RER1 | THRB 1664/4885TSHR 955/4885ALDH1A1 1281/4885 |
| US-20200048191-A1 | COMPOSITION AND METHOD FOR MANUFACTURING DEVICE USING SAME | LBR, LMTK2, MMS19 | THRB 4482/4885TSHR 2146/4885ALDH1A1 4785/4885 |
| US-11142495-B2 | Composition and method for manufacturing device using same | LBR, LMTK2, MMS19 | THRB 4482/4885TSHR 2146/4885ALDH1A1 4785/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.