Cystetine Triphosphate

Cystetine Triphosphate

SCHEMBL2194115

Nc1ccn([C@@H]2O[C@H](COP(=O)([O-])OP(=O)(O)OP(=O)([O-])O)[C@@H](O)[C@H]2O)c(=O)n1.[Na+].[Na+]

nearest known ligand 0.75

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Cystetine Triphosphate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
P2RY2 known ✓ P41231 5/20 0.67
P2RY4 known ✓ P51582 3/20 0.61
THRB known ✓ P10828 1/20 0.57
P2RY6 known ✓ Q15077 2/20 0.57
TSHR P16473 1/20 0.75
GLA P06280 1/20 0.75
ST6GAL1 P15907 10/20 0.66
LMNA P02545 1/20 0.57
MTOR P42345 1/20 0.57
MDM2 Q00987 1/20 0.57
NCOA1 Q15788 1/20 0.57
NCOA3 Q9Y6Q9 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11616961 0.95 TSHR (0.78) TSHRGLAP2RY2ST6GAL1P2RY4
Cystetine Triphosphate SCHEMBL27611738 0.94 TSHR (0.73) TSHRGLAP2RY2ST6GAL1P2RY4
Cystetine Triphosphate SCHEMBL11613107 0.94 TSHR (0.79) TSHRGLAP2RY2ST6GAL1P2RY4
SCHEMBL5407898 0.91 TSHR (0.81) TSHRGLAP2RY2ST6GAL1P2RY4
SCHEMBL29356399 0.91 TSHR (0.81) TSHRGLAP2RY2ST6GAL1P2RY4
Potassium Ion SCHEMBL10585798 0.91 TSHR (0.80) TSHRGLAP2RY2ST6GAL1P2RY4
Cystetine Triphosphate SCHEMBL2194120 0.90 TSHR (0.79) TSHRGLAP2RY2ST6GAL1P2RY4
Cystetine Triphosphate SCHEMBL9101211 0.90 TSHR (0.81) TSHRGLAP2RY2ST6GAL1P2RY4
Cystetine Triphosphate SCHEMBL31405617 0.89 TSHR (0.80) TSHRGLAP2RY2ST6GAL1P2RY4
Cystetine Triphosphate SCHEMBL10826769 0.89 TSHR (0.80) TSHRGLAP2RY2ST6GAL1P2RY4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250195689-A1 GLYCOMIMETIC LIGANDS AVICEDA THERAPEUTICS, INC. 2025-06-19 US disclosed
EP-4457235-A1 GLYCOMIMETIC LIGANDS Aviceda Therapeutics, Inc. (US) 2024-11-06 EP disclosed
US-20240189335-A1 N4-HYDROXYCYTIDINE AND DERIVATIVES AND ANTI-VIRAL USES RELATED THERETO EMORY UNIVERSITY 2024-06-13 US disclosed
US-11903959-B2 N4-hydroxycytidine and derivatives and anti-viral uses related thereto EMORY UNIVERSITY (US) 2024-02-20 US disclosed
US-20230293566-A1 N4-Hydroxycytidine and Derivatives and Anti-Viral Uses Related Thereto EMORY UNIVERSITY 2023-09-21 US disclosed
WO-2023129737-A1 GLYCOMIMETIC LIGANDS AVICEDA THERAPEUTICS, INC. (US) 2023-07-06 WO disclosed
CN-116334020-A 6' -sialyltransferase mutant and application thereof 南京工业大学 2023-06-27 CN disclosed
US-11628181-B2 N4-hydroxycytidine and derivatives and anti-viral uses related thereto EMORY UNIVERSITY (US) 2023-04-18 US disclosed
EP-4017501-A1 N4-HYDROXYCYTIDINE AND DERIVATIVES AND ANTI-VIRAL USES RELATED THERETO Emory University (US) 2022-06-29 EP disclosed
US-11331331-B2 N4-hydroxycytidine and derivatives and anti-viral uses related thereto EMORY UNIVERSITY (US) 2022-05-17 US disclosed
WO-2016106050-A1 N4-HYDROXYCYTIDINE AND DERIVATIVES AND ANTI-VIRAL USES RELATED THERETO EMORY UNIVERSITY (US) 2016-06-30 WO disclosed
CN-101658498-B Freeze-drying manufactured product of cytidine triphosphate disodium and arginine and preparation method thereof GUANGDONG P D 2012-01-04 CN disclosed
CN-101658498-B Freeze-drying manufactured product of cytidine triphosphate disodium and arginine and preparation method thereof GUANGDONG P D 2012-01-04 CN disclosed
US-20110171737-A1 PROTEIN ENGINEERING DUKE UNIVERSITY 2011-07-14 US disclosed
CN-101658498-A Freeze-drying manufactured product of cytidine triphosphate disodium and arginine and preparation method thereof GUANGDONG P D 2010-03-03 CN disclosed
CN-101658498-A Freeze-drying manufactured product of cytidine triphosphate disodium and arginine and preparation method thereof GUANGDONG P D 2010-03-03 CN disclosed
EP-1911850-A1 Method of producing 6-thio-sialylated glycoproteins and glycoconjugates CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2008-04-16 EP disclosed
CN-1660126-A Medication of combination of sodium cytidine triphosphate and ebselen YANG XIHONG (CN) 2005-08-31 CN disclosed
CN-1562345-A Drug combination including activator for metabolism of brain and free radical scavenger YANG XIHONG (CN) 2005-01-12 CN disclosed
CN-1513468-A Compound medicine of sodium citicoline and disodium cytidine triphosphate 杨喜鸿 2004-07-21 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110171737-A1 PROTEIN ENGINEERING MRPL21, RNGTT, SERBP1 P2RY2 4830/4885P2RY4 4863/4885THRB 2357/4885
US-11331331-B2 N4-hydroxycytidine and derivatives and anti-viral uses related thereto ENTPD1, NME2, NME1 P2RY2 843/4885P2RY4 232/4885THRB 4460/4885
US-20250195689-A1 GLYCOMIMETIC LIGANDS SIGLEC9, SIGLEC7, LGALS2 P2RY2 1493/4885P2RY4 1338/4885THRB 3137/4885
US-11628181-B2 N4-hydroxycytidine and derivatives and anti-viral uses related thereto TYMP, ENTPD5, ADA P2RY2 1364/4885P2RY4 592/4885THRB 4778/4885
US-11903959-B2 N4-hydroxycytidine and derivatives and anti-viral uses related thereto ENTPD1, NME2, NME1 P2RY2 843/4885P2RY4 232/4885THRB 4460/4885
US-20240189335-A1 N4-HYDROXYCYTIDINE AND DERIVATIVES AND ANTI-VIRAL USES RELATED THERETO ENTPD1, NME2, NME1 P2RY2 843/4885P2RY4 232/4885THRB 4460/4885
US-20230293566-A1 N4-Hydroxycytidine and Derivatives and Anti-Viral Uses Related Thereto TYMP, ADA, CDA P2RY2 1313/4885P2RY4 561/4885THRB 4785/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.