Cystetine Triphosphate

Cystetine Triphosphate

SCHEMBL9101211

Nc1ccn([C@@H]2O[C@H](COP(=O)([O-])OP(=O)([O-])OP(=O)([O-])[O-])[C@@H](O)[C@H]2O)c(=O)n1.[Na+].[Na+].[Na+].[Na+]

nearest known ligand 0.81

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Cystetine Triphosphate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
P2RY2 known ✓ P41231 4/20 0.69
P2RY4 known ✓ P51582 2/20 0.69
P2RY6 known ✓ Q15077 2/20 0.63
THRB known ✓ P10828 1/20 0.60
TSHR P16473 1/20 0.81
GLA P06280 1/20 0.81
ST6GAL1 P15907 10/20 0.69
LMNA P02545 1/20 0.60
MTOR P42345 1/20 0.60
MDM2 Q00987 1/20 0.60
NCOA1 Q15788 1/20 0.60
NCOA3 Q9Y6Q9 1/20 0.60
BLM P54132 1/20 0.56
PMP22 Q01453 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cystetine Triphosphate SCHEMBL31405617 0.99 TSHR (0.80) TSHRGLAST6GAL1P2RY2P2RY4
Cystetine Triphosphate SCHEMBL10826769 0.99 TSHR (0.80) TSHRGLAST6GAL1P2RY2P2RY4
SCHEMBL29356399 0.98 TSHR (0.81) TSHRGLAST6GAL1P2RY2P2RY4
SCHEMBL5407898 0.98 TSHR (0.81) TSHRGLAST6GAL1P2RY2P2RY4
Potassium Ion SCHEMBL10585798 0.97 TSHR (0.80) TSHRGLAST6GAL1P2RY2P2RY4
Cystetine Triphosphate SCHEMBL2194120 0.94 TSHR (0.79) TSHRGLAST6GAL1P2RY2P2RY4
Cystetine Triphosphate SCHEMBL11613107 0.94 TSHR (0.79) TSHRGLAST6GAL1P2RY2P2RY4
Cystetine Triphosphate SCHEMBL28754273 0.93 TSHR (0.72) TSHRGLAST6GAL1P2RY2P2RY4
Cystetine Triphosphate SCHEMBL27792998 0.92 TSHR (0.71) TSHRGLAST6GAL1P2RY2P2RY4
SCHEMBL11616961 0.92 TSHR (0.78) TSHRGLAST6GAL1P2RY2P2RY4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115613085-A Brush silver-plating alloy plating solution for repairing silver-plated layer of open-type isolating switch and preparation method thereof 国网山东省电力公司电力科学研究院 2023-01-17 CN claimed
CN-108265094-B Preparation method of alpha-2, 3 deaminated sialyllactulose 河南科技学院 2021-03-19 CN claimed
CN-105106240-A Novel stem cell preparation and application thereof in vascular intervention therapy of cerebral apoplexy JIANGSU STEM CELL OSDBIO CO LTD 2015-12-02 CN claimed
CN-104906055-A Preparation method of cytidine disdoium triphosphate freeze-dried powder injection HUNAN KELUN PHARMACEUTICAL CO 2015-09-16 CN claimed
CN-102614135-B Cytidine disodium triphosphate suspension powder injection and preparation method thereof ZHEJIANG PANGU PHARMACEUTICAL CO LTD 2013-08-14 CN claimed
CN-101569611-B Lyophilized cytidine disodium triphosphate powder needle reagent for injection HANGZHOU AOYA BIO TECH CO LTD 2011-05-11 CN claimed
CN-101658498-A Freeze-drying manufactured product of cytidine triphosphate disodium and arginine and preparation method thereof GUANGDONG P D 2010-03-03 CN claimed
CN-101569611-A Lyophilized cytidine disodium triphosphate powder needle reagent for injection HANGZHOU AOYA BIO TECH CO LTD (CN) 2009-11-04 CN claimed
CN-101518515-A Cytidine disodium triphosphate freeze-dried powder-injection for injection KELUN PHARMACEUTICAL RES CO LT 2009-09-02 CN claimed
CN-100528174-C Combination of cytidine disodium triphosphate and arginine, and preparation method thereof NING HUI QU HAIJUN JING FANBO (CN) 2009-08-19 CN claimed
CN-101390873-A Cytidine disodium triphosphate and arginine composition and preparation method thereof HUI NING (CN) 2009-03-25 CN claimed
CN-100370995-C Sodium triphosphate transfusion and its prepn. technique SHANTOU CITY JIANXIN MEDICAMEN (CN) 2008-02-27 CN claimed
CN-1833655-A Sodium triphosphate transfusion and its prepn. technique JIANXIN MEDICAMENTS CO LTD SHA (CN) 2006-09-20 CN claimed
CN-1660126-A Medication of combination of sodium cytidine triphosphate and ebselen YANG XIHONG (CN) 2005-08-31 CN claimed
CN-1616104-A Transfusion medicine prepared from xylitol as istonic regulator and various injections separately and its preparing method CUI XIAOTING (CN) 2005-05-18 CN claimed
CN-1579412-A Cytidine triphosphate disodium chloride injecta and its preparation process JIANG WEISHI (CN) 2005-02-16 CN claimed
CN-1562345-A Drug combination including activator for metabolism of brain and free radical scavenger YANG XIHONG (CN) 2005-01-12 CN claimed
CN-1557331-A Oral prescription of cytidine triphosphate 杨喜鸿 2004-12-29 CN claimed
CN-1513468-A Compound medicine of sodium citicoline and disodium cytidine triphosphate 杨喜鸿 2004-07-21 CN claimed
US-20230383287-A1 ACETYLATED RIBONUCLEIC ACIDS AND USES THEREOF HELIX NANOTECHNOLOGIES INC 2023-11-30 US disclosed
WO-2023215516-A2 ACETYLATED RIBONUCLEIC ACIDS AND USES THEREOF HELIX NANOTECHNOLOGIES, INC. (US) 2023-11-09 WO disclosed
CN-115613085-A Brush silver-plating alloy plating solution for repairing silver-plated layer of open-type isolating switch and preparation method thereof 国网山东省电力公司电力科学研究院 2023-01-17 CN disclosed
CN-107737339-B Calcium phosphate-biomolecule composite material and preparation method thereof 中国科学院上海硅酸盐研究所 2021-06-15 CN disclosed
CN-108265094-B Preparation method of alpha-2, 3 deaminated sialyllactulose 河南科技学院 2021-03-19 CN disclosed
CN-108265094-B Preparation method of alpha-2, 3 deaminated sialyllactulose 河南科技学院 2021-03-19 CN disclosed
US-10195226-B2 Medicinal carbohydrates for treatment of respiratory conditions AUSTRALIAN BIOMEDICAL COMPANY PTY LTD. (AU) 2019-02-05 US disclosed
EP-2448590-B1 MEDICINAL CARBOHYDRATES FOR TREATMENT OF RESPIRATORY CONDITIONS AUSTRALIAN BIOMEDICAL COMPANY PTY LTD (AU) 2018-10-31 EP disclosed
CN-106632531-A Method for preparing alpha-2,3glycolyl sialic acid lactulose 河南科技学院 2017-05-10 CN disclosed
CN-105949250-A Preparation method of alpha-2,3-sialyllactulose 河南科技学院 2016-09-21 CN disclosed
CN-105457035-A Accessory for injection or oral taking ZHONG SHUGUANG 2016-04-06 CN disclosed
CN-105106240-A Novel stem cell preparation and application thereof in vascular intervention therapy of cerebral apoplexy JIANGSU STEM CELL OSDBIO CO LTD 2015-12-02 CN disclosed
CN-105031108-A Medicine for treating chronic amyotrophic lateral sclerosis JIANG SHIFEN 2015-11-11 CN disclosed
CN-104906055-A Preparation method of cytidine disdoium triphosphate freeze-dried powder injection HUNAN KELUN PHARMACEUTICAL CO 2015-09-16 CN disclosed
US-20150238512-A1 MEDICINAL CARBOHYDRATES FOR TREATMENT OF RESPIRATORY CONDITIONS AUSTRALIAN BIOMEDICAL COMPANY PTY LTD (AU) 2015-08-27 US disclosed
US-9040503-B2 Medicinal carbohydrates for treatment of respiratory conditions AUSTRALIAN BIOMEDICAL COMPANY PTY LTD. (AU) 2015-05-26 US disclosed
CN-102614135-B Cytidine disodium triphosphate suspension powder injection and preparation method thereof ZHEJIANG PANGU PHARMACEUTICAL CO LTD 2013-08-14 CN disclosed
US-20120142619-A1 MEDICINAL CARBOHYDRATES FOR TREATMENT OF RESPIRATORY CONDITIONS Australian Blomedical Company Pty Ltd, (AU) 2012-06-07 US disclosed
CN-101569611-B Lyophilized cytidine disodium triphosphate powder needle reagent for injection HANGZHOU AOYA BIO TECH CO LTD 2011-05-11 CN disclosed
CN-101658498-A Freeze-drying manufactured product of cytidine triphosphate disodium and arginine and preparation method thereof GUANGDONG P D 2010-03-03 CN disclosed
CN-101569611-A Lyophilized cytidine disodium triphosphate powder needle reagent for injection HANGZHOU AOYA BIO TECH CO LTD (CN) 2009-11-04 CN disclosed
CN-101518515-A Cytidine disodium triphosphate freeze-dried powder-injection for injection KELUN PHARMACEUTICAL RES CO LT 2009-09-02 CN disclosed
CN-100528174-C Combination of cytidine disodium triphosphate and arginine, and preparation method thereof NING HUI QU HAIJUN JING FANBO (CN) 2009-08-19 CN disclosed
CN-101390873-A Cytidine disodium triphosphate and arginine composition and preparation method thereof HUI NING (CN) 2009-03-25 CN disclosed
CN-100370995-C Sodium triphosphate transfusion and its prepn. technique SHANTOU CITY JIANXIN MEDICAMEN (CN) 2008-02-27 CN disclosed
CN-1833655-A Sodium triphosphate transfusion and its prepn. technique JIANXIN MEDICAMENTS CO LTD SHA (CN) 2006-09-20 CN disclosed
CN-1660126-A Medication of combination of sodium cytidine triphosphate and ebselen YANG XIHONG (CN) 2005-08-31 CN disclosed
CN-1660126-A Medication of combination of sodium cytidine triphosphate and ebselen YANG XIHONG (CN) 2005-08-31 CN disclosed
CN-1579412-A Cytidine triphosphate disodium chloride injecta and its preparation process JIANG WEISHI (CN) 2005-02-16 CN disclosed
CN-1562345-A Drug combination including activator for metabolism of brain and free radical scavenger YANG XIHONG (CN) 2005-01-12 CN disclosed
CN-1557331-A Oral prescription of cytidine triphosphate 杨喜鸿 2004-12-29 CN disclosed
CN-1513468-A Compound medicine of sodium citicoline and disodium cytidine triphosphate 杨喜鸿 2004-07-21 CN disclosed
EP-0278005-A1 DNA FOR SHUTTLE VECTOR TAIYO KAGAKU Co., LTD. (JP) 1988-08-17 EP disclosed
EP-0278005-A1 DNA FOR SHUTTLE VECTOR TAIYO KAGAKU Co., LTD. (JP) 1988-08-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230383287-A1 ACETYLATED RIBONUCLEIC ACIDS AND USES THEREOF NSUN2, NSUN3, ADAR P2RY2 3581/4885P2RY4 3754/4885P2RY6 3557/4885
US-20150238512-A1 MEDICINAL CARBOHYDRATES FOR TREATMENT OF RESPIRATORY CONDITIONS FUT6, NEU3, FUT5 P2RY2 4012/4885P2RY4 3796/4885P2RY6 3285/4885
US-20120142619-A1 MEDICINAL CARBOHYDRATES FOR TREATMENT OF RESPIRATORY CONDITIONS FUT6, ST6GAL1, FUT5 P2RY2 2729/4885P2RY4 2374/4885P2RY6 2539/4885
US-10195226-B2 Medicinal carbohydrates for treatment of respiratory conditions FUT6, NEU3, FUT5 P2RY2 4012/4885P2RY4 3796/4885P2RY6 3285/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.