SCHEMBL22080172

SCHEMBL22080172

Cc1ccc(-c2cc(C)c(C(C)(C)C)cn2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LDHA P00338 1/20 0.39
▸ METAP2 P50579 1/20 0.38
▸ METAP1 P53582 1/20 0.38
▸ CYP11B1 P15538 1/20 0.38
▸ CYP11B2 P19099 1/20 0.38
▸ CCR1 P32246 1/20 0.38
▸ CCR5 P51681 1/20 0.38
▸ CCR8 P51685 1/20 0.38
▸ HDAC6 Q9UBN7 1/20 0.38
▸ KDM1A O60341 1/20 0.37
▸ KMT2A Q03164 2/20 0.35
▸ KDM4E B2RXH2 2/20 0.35
▸ ALDH1A1 P00352 2/20 0.35
▸ HPGD P15428 2/20 0.35
▸ MEN1 O00255 1/20 0.35
▸ MAPT P10636 1/20 0.35
▸ TDP1 Q9NUW8 1/20 0.35
▸ L3MBTL1 Q9Y468 1/20 0.35
▸ TDO2 P48775 1/20 0.35
▸ TSHR P16473 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22675050 0.87 METAP2 (0.39) METAP2METAP1CYP11B1CYP11B2CCR1
SCHEMBL24701251 0.86 LDHA (0.54) LDHACYP11B1CYP11B2KMT2AKDM4E
SCHEMBL22079793 0.83 LDHA (0.36) LDHAMETAP2METAP1CYP11B1CYP11B2
SCHEMBL24066428 0.83 LDHA (0.36) LDHAMETAP2METAP1CYP11B1CYP11B2
SCHEMBL26477339 0.80 XDH (0.40) LDHAKMT2AKDM4EMEN1MAPT
SCHEMBL24292157 0.79 ALPL (0.38) CCR1CCR5CCR8HDAC6KDM1A
SCHEMBL18729621 0.79 CCR1 (0.44) LDHAMETAP2METAP1CCR1CCR5
SCHEMBL25796037 0.77 CYP11B1 (0.37) METAP2METAP1CYP11B1CYP11B2CCR1
SCHEMBL2187669 0.76 LDHA (0.46) LDHAMETAP2METAP1CCR1CCR5
SCHEMBL23561573 0.75 CYP11B1 (0.35) METAP2METAP1CYP11B1CYP11B2CCR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11864458-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-01-02 — — US disclosed
US-11839141-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-12-05 — — US disclosed
US-20230365606-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-16 — — US disclosed
US-20230345811-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-26 — — US disclosed
US-20230331757-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 — — US disclosed
US-20230320188-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-05 — — US disclosed
US-20230303601-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-28 — — US disclosed
US-20230287011-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-14 — — US disclosed
US-20230292606-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-14 — — US disclosed
US-11746122-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-09-05 — — US disclosed
US-20230029347-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-01-26 — — US disclosed
US-20220402954-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-12-22 — — US disclosed
US-20220402953-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSITY DISPLAY CORPORATION (US) 2022-12-22 — — US disclosed
US-20220194974-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-06-23 — — US disclosed
US-20220135606-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-05-05 — — US disclosed
US-20210380617-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-12-09 — — US disclosed
US-20210288269-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-09-16 — — US disclosed
US-20210167302-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-06-03 — — US disclosed
US-20210104690-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-04-08 — — US disclosed
US-20200181182-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-06-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (18 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220402954-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES CTCF, CCNY, RUVBL2 LDHA 2130/4885METAP2 4246/4885METAP1 4499/4885
US-20220135606-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES GLRA3, GLRA2, LIFR LDHA 2081/4885METAP2 4053/4885METAP1 4522/4885
US-20230303601-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES MGLL, SELENOI, APOL1 LDHA 1714/4885METAP2 3418/4885METAP1 3798/4885
US-11746122-B2 Organic electroluminescent materials and devices GLRA3, GLRA2, LIFR LDHA 2081/4885METAP2 4053/4885METAP1 4522/4885
US-20230320188-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, MLX LDHA 452/4885METAP2 4654/4885METAP1 4569/4885
US-20230029347-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, OSBP LDHA 100/4885METAP2 4638/4885METAP1 4397/4885
US-20220194974-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OTC LDHA 539/4885METAP2 2978/4885METAP1 3749/4885
US-20230287011-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OXGR1, OCIAD1 LDHA 273/4885METAP2 4476/4885METAP1 4743/4885
US-11839141-B2 Organic electroluminescent materials and devices OSBP, OCIAD1, OCIAD2 LDHA 319/4885METAP2 3731/4885METAP1 4032/4885
US-11864458-B2 Organic electroluminescent materials and devices RAP1A, L1CAM, SOD1 LDHA 73/4885METAP2 4831/4885METAP1 4762/4885
US-20200181182-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, ICOSLG LDHA 534/4885METAP2 3796/4885METAP1 3430/4885
US-20230331757-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, SSB, L1CAM LDHA 297/4885METAP2 4607/4885METAP1 4688/4885
US-20210288269-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, OXA1L LDHA 86/4885METAP2 4841/4885METAP1 4803/4885
US-20220402953-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, OSBP LDHA 119/4885METAP2 3975/4885METAP1 3797/4885
US-20230365606-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OXER1, OPRD1, OXSR1 LDHA 981/4885METAP2 4826/4885METAP1 4771/4885
US-20210380617-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES SOD1, CRKL, ROS1 LDHA 609/4885METAP2 4123/4885METAP1 4277/4885
US-20210104690-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES RAP1A, L1CAM, SOD1 LDHA 73/4885METAP2 4831/4885METAP1 4762/4885
US-20230345811-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OPRD1, L1CAM, OPRM1 LDHA 1161/4885METAP2 3011/4885METAP1 2676/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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