Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 11/20 | 0.38 |
| ▸ | FAAH | O00519 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | WRN | Q14191 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6480093 | 0.71 | MGLL (0.48) | MGLLFAAHALDH1A1BLMLMNA | |
| SCHEMBL24854625 | 0.68 | MGLL (0.44) | MGLLFAAHALDH1A1BLMLMNA | |
| SCHEMBL28836760 | 0.68 | MGLL (0.43) | MGLLFAAHALDH1A1BLMLMNA | |
| SCHEMBL145760 | 0.66 | MGLL (0.56) | MGLLFAAHALDH1A1BLMLMNA | |
| SCHEMBL88581 | 0.66 | CASP3 (0.48) | MGLLFAAHALDH1A1BLMLMNA | |
| SCHEMBL8747671 | 0.65 | ALDH1A1 (0.53) | MGLLFAAHALDH1A1BLMLMNA | |
| SCHEMBL7980544 | 0.65 | MGLL (0.41) | MGLLFAAHALDH1A1BLMLMNA | |
| SCHEMBL22264531 | 0.62 | MGLL (0.52) | MGLLFAAHALDH1A1BLMLMNA | |
| SCHEMBL8510666 | 0.62 | MGLL (0.48) | MGLLFAAHALDH1A1BLMLMNA | |
| SCHEMBL277926 | 0.62 | MGLL (0.55) | MGLLFAAHALDH1A1BLMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2132248-B1 | ALDIMINES WITH REACTIVE GROUPS COMPRISING ACTIVE HYDROGEN | SIKA TECHNOLOGY AG (CH) | 2016-07-13 | — | — | EP | disclosed |
| US-8519038-B2 | Aldimines and compositions comprising aldimine | SIKA TECHNOLOGY AG (CH) | 2013-08-27 | — | — | US | disclosed |
| US-20120220736-A1 | ALDIMINES AND COMPOSITIONS COMPRISING ALDIMINE | SIKA TECHNOLOGY AG (CH) | 2012-08-30 | — | — | US | disclosed |
| US-8252859-B2 | Aldimines and compositions comprising aldimine | SIKA TECHNOLOGY AG (CH) | 2012-08-28 | — | — | US | disclosed |
| EP-1934172-B1 | COMPOUNDS CONTAINING ALDIMINE | SIKA TECHNOLOGY AG (CH) | 2011-09-28 | — | — | EP | disclosed |
| US-20100101455-A1 | ALDIMINES AND COMPOSITIONS COMPRISING ALDIMINE | SIKA TECHNOLOGY AG (CH) | 2010-04-29 | — | — | US | disclosed |
| EP-2178828-A1 | ALDIMINES AND COMPOSITIONS COMPRISING ALDAMINE | Sika Technology AG (CH) | 2010-04-28 | — | — | EP | disclosed |
| EP-2132248-A1 | ALDIMINES WITH REACTIVE GROUPS COMPRISING ACTIVE HYDROGEN | Sika Technology AG (CH) | 2009-12-16 | — | — | EP | disclosed |
| US-7629433-B2 | Odor-less during hydrolytic deblocking, separation; for use as source for aldehydes; crosslinking agents | SIKA TECHNOLOGY AG (CH) | 2009-12-08 | — | — | US | disclosed |
| US-20090176944-A1 | Aldimines Comprising Reactive Groups Containing Active Hydrogen, and Use Thereof | SIKA TECHNOLOGY AG (CH) | 2009-07-09 | — | — | US | disclosed |
| WO-2009010522-A1 | ALDIMINES AND COMPOSITIONS COMPRISING ALDAMINE | SIKA TECHNOLOGY AG (CH) | 2009-01-22 | — | — | WO | disclosed |
| EP-2017260-A1 | Aldimines and compounds containing aldimine | Sika Technology AG (CH) | 2009-01-21 | — | — | EP | disclosed |
| WO-2008116928-A1 | ALDIMINES WITH REACTIVE GROUPS COMPRISING ACTIVE HYDROGEN | SIKA TECHNOLOGY AG (CH) | 2008-10-02 | — | — | WO | disclosed |
| EP-1975190-A1 | Aldimines with reactive groups containing active hydrogen | Sika Technology AG (CH) | 2008-10-01 | — | — | EP | disclosed |
| EP-1934169-A1 | ALDIMINES COMPRISING REACTIVE GROUPS CONTAINING ACTIVE HYDROGEN, AND USE THEREOF | Sika Technology AG (CH) | 2008-06-25 | — | — | EP | disclosed |
| EP-1934172-A1 | COMPOUNDS CONTAINING ALDIMINE | Sika Technology AG (CH) | 2008-06-25 | — | — | EP | disclosed |
| EP-1775284-A1 | Compounds comprising aldimine groups | Sika Technology AG (CH) | 2007-04-18 | — | — | EP | disclosed |
| EP-1772447-A1 | Aldimines with reactive groups comprising active hydrogen, and their use | Sika Technology AG (CH) | 2007-04-11 | — | — | EP | disclosed |
| WO-2007036572-A1 | COMPOUNDS CONTAINING ALDIMINE | SIKA TECHNOLOGY AG (CH) | 2007-04-05 | — | — | WO | disclosed |
| WO-2007036571-A1 | ALDIMINES COMPRISING REACTIVE GROUPS CONTAINING ACTIVE HYDROGEN, AND USE THEREOF | SIKA TECHNOLOGY AG (CH) | 2007-04-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120220736-A1 | ALDIMINES AND COMPOSITIONS COMPRISING ALDIMINE | ALDOA, ALDH7A1, ALDH3A1 | MGLL 2518/4885FAAH 1394/4885ALDH1A1 6/4885 |
| US-20100101455-A1 | ALDIMINES AND COMPOSITIONS COMPRISING ALDIMINE | ALDH7A1, ILK, ALDH3A1 | MGLL 2157/4885FAAH 2183/4885ALDH1A1 5/4885 |
| US-20090176944-A1 | Aldimines Comprising Reactive Groups Containing Active Hydrogen, and Use Thereof | ADH5, ADH1C, ADH1A | MGLL 1258/4885FAAH 551/4885ALDH1A1 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.