SCHEMBL2516306

SCHEMBL2516306

O=C(O)Cc1ccc(C=Cc2cc(O)cc(CC(=O)O)c2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CA2 P00918 3/20 0.53
▸ CAMK2A Q9UQM7 1/20 0.53
▸ KDM4E B2RXH2 4/20 0.48
▸ LMNA P02545 4/20 0.48
▸ PTGS2 P35354 4/20 0.48
▸ PTGS1 P23219 4/20 0.48
▸ MAPT P10636 3/20 0.48
▸ HPGD P15428 3/20 0.48
▸ HIF1A Q16665 3/20 0.48
▸ HSD17B10 Q99714 3/20 0.48
▸ CYP1A2 P05177 3/20 0.48
▸ CYP19A1 P11511 3/20 0.48
▸ CYP1A1 P04798 3/20 0.48
▸ CA12 O43570 2/20 0.48
▸ CA1 P00915 2/20 0.48
▸ CA3 P07451 2/20 0.48
▸ CA4 P22748 2/20 0.48
▸ CA6 P23280 2/20 0.48
▸ CA5A P35218 2/20 0.48
▸ CA7 P43166 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2521051 0.93 CA2 (0.58) CA2CAMK2AKDM4ELMNAPTGS2
SCHEMBL2517179 0.93 PTGS1 (0.57) CA2CAMK2AKDM4ELMNAPTGS2
SCHEMBL2520048 0.90 CA2 (0.50) CA2CAMK2AKDM4ELMNAPTGS1
SCHEMBL2519142 0.86 CA2 (0.57) CA2CAMK2AKDM4ELMNAPTGS2
SCHEMBL16888910 0.86 CA2 (0.54) CA2CAMK2AKDM4ELMNAPTGS1
SCHEMBL22046126 0.84 CA2 (0.76) CA2CAMK2AKDM4ELMNAPTGS2
SCHEMBL18109184 0.80 AKR1B1 (0.46) CA2CAMK2AKDM4ELMNAPTGS1
SCHEMBL6312946 0.78 AKR1B1 (0.64) CA2CAMK2ALMNAPTGS1MAPT
SCHEMBL6313137 0.78 AKR1B1 (0.64) CA2CAMK2ALMNAPTGS1MAPT
SCHEMBL4209130 0.78 CA2 (0.58) CA2KDM4ELMNAPTGS2PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9861564-B2 Valeric acid esters of resveratrol and cosmetic compositions ELC MANAGEMENT, LLC (US) 2018-01-09 — — US disclosed
US-9782335-B2 Malic acid esters of resveratrol and cosmetic compositions ELC MANAGEMENT LLC (US) 2017-10-10 — — US disclosed
US-20160303016-A1 Valeric Acid Esters Of Resveratrol And Cosmetic Compositions ELC MAN LLC (US) 2016-10-20 — — US disclosed
EP-2445511-B1 SKIN REPAIR COMPOSITIONS COMPRISING CIRCADIAN GENE ACTIVATORS AND A SYNERGISTIC COMBINATION OF SIRT1 GENE ACTIVATORS ELC MAN LLC (US) 2016-09-07 — — EP disclosed
US-20160229791-A1 Malic Acid Esters Of Resveratrol And Cosmetic Compositions ELC MAN LLC (US) 2016-08-11 — — US disclosed
US-9358194-B2 Succinic acid esters of resveratrol and cosmetic compositions ELC MANAGEMENT LLC (US) 2016-06-07 — — US disclosed
US-9295621-B2 Emulsion cosmetic compositions containing resveratrol derivatives and silicone surfactant ELC MANAGEMENT LLC (US) 2016-03-29 — — US disclosed
US-20160038389-A1 Succinic Acid Esters Of Resveratrol And Cosmetic Compositions ELC MAN LLC (US) 2016-02-11 — — US disclosed
US-9180316-B2 Butyric acid esters of resveratrol and cosmetic compositions ELC MANAGEMENT LLC (US) 2015-11-10 — — US disclosed
US-9162083-B2 Linoleic and Linolenic acid esters of resveratrol and cosmetic compositions ELC MANAGEMENT LLC (US) 2015-10-20 — — US disclosed
US-20100216879-A1 Resveratrol Ferulate Compounds And Compositions MAES DANIEL H 2010-08-26 — — US disclosed
EP-2185128-A1 COSMETIC COMPOSITIONS CONTAINING RESVERATROL DERIVATIVES ELC Management LLC (US) 2010-05-19 — — EP disclosed
US-20100080845-A1 Cosmetic Methods And Compositions For Repairing Human Skin MAES DANIEL H 2010-04-01 — — US disclosed
US-20090047309-A1 COSMETIC METHODS AND COMPOSITIONS FOR REPAIRING HUMAN SKIN ELC MANAGEMENT LLC 2009-02-19 — — US disclosed
US-20090035243-A1 Anhydrous Cosmetic Compositions Containing Resveratrol Derivatives ELC MANAGEMENT LLC 2009-02-05 — — US disclosed
US-20090035240-A1 Aqueous Based Cosmetic Compositions Containing Resveratrol Derivatives And An Aqueous Phase Structuring Agent ELC MANAGEMENT LLC 2009-02-05 — — US disclosed
US-20090035242-A1 Emulsion Cosmetic Compositions Containing Resveratrol Derivatives And Linear Or Branched Silicone ELC MANAGEMENT LLC 2009-02-05 — — US disclosed
US-20090035237-A1 Emulsion Cosmetic Compositions Containing Resveratrol Derivatives And Silicone Surfactant ELC MANAGEMENT LLC 2009-02-05 — — US disclosed
WO-2009017866-A1 COSMETIC COMPOSITIONS CONTAINING RESVERATROL DERIVATIVES ELC MANAGEMENT LLC (US) 2009-02-05 — — WO disclosed
US-20090035236-A1 Emulsion Cosmetic Compositions Containing Resveratrol Derivatives And An Oil Phase Structuring Agent ELC MANAGEMENT LLC 2009-02-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090035243-A1 Anhydrous Cosmetic Compositions Containing Resveratrol Derivatives RB1, SIRT1, EP300 CA2 1489/4885CAMK2A 3900/4885KDM4E 506/4885
US-20090035242-A1 Emulsion Cosmetic Compositions Containing Resveratrol Derivatives And Linear Or Branched Silicone SQLE, SMURF1, PIK3R1 CA2 4594/4885CAMK2A 4418/4885KDM4E 1188/4885
US-20100216879-A1 Resveratrol Ferulate Compounds And Compositions FER, FOLR1, FOLR2 CA2 2891/4885CAMK2A 3811/4885KDM4E 1158/4885
US-20090047309-A1 COSMETIC METHODS AND COMPOSITIONS FOR REPAIRING HUMAN SKIN CUTA, ERCC1, OGG1 CA2 3488/4885CAMK2A 4775/4885KDM4E 1584/4885
US-20160303016-A1 Valeric Acid Esters Of Resveratrol And Cosmetic Compositions CUTA, SUV39H1, RARA CA2 1711/4885CAMK2A 2685/4885KDM4E 450/4885
US-20090035237-A1 Emulsion Cosmetic Compositions Containing Resveratrol Derivatives And Silicone Surfactant SMURF1, CUTA, SMURF2 CA2 4638/4885CAMK2A 4495/4885KDM4E 1074/4885
US-20090035236-A1 Emulsion Cosmetic Compositions Containing Resveratrol Derivatives And An Oil Phase Structuring Agent CUTA, LRAT, RARA CA2 4591/4885CAMK2A 3560/4885KDM4E 1813/4885
US-20090035240-A1 Aqueous Based Cosmetic Compositions Containing Resveratrol Derivatives And An Aqueous Phase Structuring Agent SMARCC1, RARG, RARA CA2 4547/4885CAMK2A 4542/4885KDM4E 2286/4885
US-20100080845-A1 Cosmetic Methods And Compositions For Repairing Human Skin CUTA, ERCC1, OGG1 CA2 3488/4885CAMK2A 4775/4885KDM4E 1584/4885
US-20160229791-A1 Malic Acid Esters Of Resveratrol And Cosmetic Compositions ME1, ME2, ME3 CA2 1368/4885CAMK2A 1806/4885KDM4E 421/4885
US-20160038389-A1 Succinic Acid Esters Of Resveratrol And Cosmetic Compositions SUCNR1, SIRT1, SUCLA2 CA2 1319/4885CAMK2A 2225/4885KDM4E 368/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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