SCHEMBL2519142

SCHEMBL2519142

O=C(O)Cc1cc(C=Cc2ccc(O)cc2)cc(CC(=O)O)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CA2 P00918 4/20 0.57
▸ CAMK2A Q9UQM7 2/20 0.57
▸ CA12 O43570 4/20 0.53
▸ CA4 P22748 4/20 0.53
▸ CA6 P23280 4/20 0.53
▸ CA5A P35218 4/20 0.53
▸ CA7 P43166 4/20 0.53
▸ CA9 Q16790 4/20 0.53
▸ CA14 Q9ULX7 4/20 0.53
▸ CA5B Q9Y2D0 4/20 0.53
▸ AKR1B1 P15121 4/20 0.53
▸ CA1 P00915 3/20 0.53
▸ CA3 P07451 3/20 0.53
▸ TYR P14679 3/20 0.53
▸ AKR1B10 O60218 3/20 0.53
▸ ESR1 P03372 2/20 0.53
▸ PKM P14618 2/20 0.53
▸ DPP4 P27487 2/20 0.53
▸ HCAR2 Q8TDS4 1/20 0.53
▸ ESR2 Q92731 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2521051 0.93 CA2 (0.58) CA2CAMK2ACA12CA4CA6
SCHEMBL2520048 0.89 CA2 (0.50) CA2CAMK2AAKR1B1KDM4EMEN1
SCHEMBL22046126 0.87 CA2 (0.76) CA2CAMK2ACA12CA4CA6
SCHEMBL18109184 0.87 AKR1B1 (0.46) CA2CAMK2AAKR1B1KDM4EMEN1
SCHEMBL2516306 0.86 CA2 (0.53) CA2CAMK2ACA12CA4CA6
SCHEMBL2517179 0.82 PTGS1 (0.57) CA2CAMK2ACA12CA4CA6
SCHEMBL16888910 0.81 CA2 (0.54) CA2CAMK2AAKR1B1KDM4EMEN1
SCHEMBL2517612 0.79 ALB (0.55) CA2CA12CA4CA6CA5A
Resveratrol SCHEMBL30291837 0.77 PTGS2 (0.66) CA2CA12CA4CA6CA5A
Resveratrol SCHEMBL19331480 0.76 PTGS2 (0.70) CA2CA12CA4CA6CA5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9861564-B2 Valeric acid esters of resveratrol and cosmetic compositions ELC MANAGEMENT, LLC (US) 2018-01-09 — — US disclosed
US-9782335-B2 Malic acid esters of resveratrol and cosmetic compositions ELC MANAGEMENT LLC (US) 2017-10-10 — — US disclosed
US-20160303016-A1 Valeric Acid Esters Of Resveratrol And Cosmetic Compositions ELC MAN LLC (US) 2016-10-20 — — US disclosed
EP-2445511-B1 SKIN REPAIR COMPOSITIONS COMPRISING CIRCADIAN GENE ACTIVATORS AND A SYNERGISTIC COMBINATION OF SIRT1 GENE ACTIVATORS ELC MAN LLC (US) 2016-09-07 — — EP disclosed
US-20160229791-A1 Malic Acid Esters Of Resveratrol And Cosmetic Compositions ELC MAN LLC (US) 2016-08-11 — — US disclosed
US-9358194-B2 Succinic acid esters of resveratrol and cosmetic compositions ELC MANAGEMENT LLC (US) 2016-06-07 — — US disclosed
US-9295621-B2 Emulsion cosmetic compositions containing resveratrol derivatives and silicone surfactant ELC MANAGEMENT LLC (US) 2016-03-29 — — US disclosed
US-20160038389-A1 Succinic Acid Esters Of Resveratrol And Cosmetic Compositions ELC MAN LLC (US) 2016-02-11 — — US disclosed
US-9180316-B2 Butyric acid esters of resveratrol and cosmetic compositions ELC MANAGEMENT LLC (US) 2015-11-10 — — US disclosed
US-9162083-B2 Linoleic and Linolenic acid esters of resveratrol and cosmetic compositions ELC MANAGEMENT LLC (US) 2015-10-20 — — US disclosed
US-8084496-B2 Resveratrol ferulate compounds and compositions ELC MANAGEMENT LLC (US) 2011-12-27 — — US disclosed
US-20110250251-A1 Cosmetic Methods And Compositions For Repairing Human Skin MAES DANIEL H 2011-10-13 — — US disclosed
US-20100216879-A1 Resveratrol Ferulate Compounds And Compositions MAES DANIEL H 2010-08-26 — — US disclosed
US-20100080845-A1 Cosmetic Methods And Compositions For Repairing Human Skin MAES DANIEL H 2010-04-01 — — US disclosed
US-20090047309-A1 COSMETIC METHODS AND COMPOSITIONS FOR REPAIRING HUMAN SKIN ELC MANAGEMENT LLC 2009-02-19 — — US disclosed
US-20090035243-A1 Anhydrous Cosmetic Compositions Containing Resveratrol Derivatives ELC MANAGEMENT LLC 2009-02-05 — — US disclosed
US-20090035240-A1 Aqueous Based Cosmetic Compositions Containing Resveratrol Derivatives And An Aqueous Phase Structuring Agent ELC MANAGEMENT LLC 2009-02-05 — — US disclosed
US-20090035242-A1 Emulsion Cosmetic Compositions Containing Resveratrol Derivatives And Linear Or Branched Silicone ELC MANAGEMENT LLC 2009-02-05 — — US disclosed
US-20090035237-A1 Emulsion Cosmetic Compositions Containing Resveratrol Derivatives And Silicone Surfactant ELC MANAGEMENT LLC 2009-02-05 — — US disclosed
US-20090035236-A1 Emulsion Cosmetic Compositions Containing Resveratrol Derivatives And An Oil Phase Structuring Agent ELC MANAGEMENT LLC 2009-02-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090035243-A1 Anhydrous Cosmetic Compositions Containing Resveratrol Derivatives RB1, SIRT1, EP300 CA2 1489/4885CAMK2A 3900/4885CA12 4257/4885
US-20090035242-A1 Emulsion Cosmetic Compositions Containing Resveratrol Derivatives And Linear Or Branched Silicone SQLE, SMURF1, PIK3R1 CA2 4594/4885CAMK2A 4418/4885CA12 4731/4885
US-20100216879-A1 Resveratrol Ferulate Compounds And Compositions FER, FOLR1, FOLR2 CA2 2891/4885CAMK2A 3811/4885CA12 2956/4885
US-20090047309-A1 COSMETIC METHODS AND COMPOSITIONS FOR REPAIRING HUMAN SKIN CUTA, ERCC1, OGG1 CA2 3488/4885CAMK2A 4775/4885CA12 4668/4885
US-20110250251-A1 Cosmetic Methods And Compositions For Repairing Human Skin CUTA, ERCC1, OGG1 CA2 3488/4885CAMK2A 4775/4885CA12 4668/4885
US-20160303016-A1 Valeric Acid Esters Of Resveratrol And Cosmetic Compositions CUTA, SUV39H1, RARA CA2 1711/4885CAMK2A 2685/4885CA12 3566/4885
US-20090035237-A1 Emulsion Cosmetic Compositions Containing Resveratrol Derivatives And Silicone Surfactant SMURF1, CUTA, SMURF2 CA2 4638/4885CAMK2A 4495/4885CA12 4775/4885
US-20090035236-A1 Emulsion Cosmetic Compositions Containing Resveratrol Derivatives And An Oil Phase Structuring Agent CUTA, LRAT, RARA CA2 4591/4885CAMK2A 3560/4885CA12 4769/4885
US-20090035240-A1 Aqueous Based Cosmetic Compositions Containing Resveratrol Derivatives And An Aqueous Phase Structuring Agent SMARCC1, RARG, RARA CA2 4547/4885CAMK2A 4542/4885CA12 4809/4885
US-20100080845-A1 Cosmetic Methods And Compositions For Repairing Human Skin CUTA, ERCC1, OGG1 CA2 3488/4885CAMK2A 4775/4885CA12 4668/4885
US-20160229791-A1 Malic Acid Esters Of Resveratrol And Cosmetic Compositions ME1, ME2, ME3 CA2 1368/4885CAMK2A 1806/4885CA12 3341/4885
US-20160038389-A1 Succinic Acid Esters Of Resveratrol And Cosmetic Compositions SUCNR1, SIRT1, SUCLA2 CA2 1319/4885CAMK2A 2225/4885CA12 3089/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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