SCHEMBL2519465

SCHEMBL2519465

CC(=O)C(=O)Oc1ccc(C=Cc2cc(O)cc(O)c2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PTGS2 P35354 5/20 0.59
▸ PTGS1 P23219 5/20 0.59
▸ KDM4E B2RXH2 4/20 0.59
▸ LMNA P02545 4/20 0.59
▸ CYP1A1 P04798 3/20 0.59
▸ CYP1B1 Q16678 3/20 0.59
▸ ALOX12 P18054 1/20 0.59
▸ MEN1 O00255 4/20 0.58
▸ MAPT P10636 4/20 0.58
▸ KMT2A Q03164 4/20 0.58
▸ TP53 P04637 3/20 0.58
▸ CYP3A4 P08684 3/20 0.58
▸ SMN1; SMN2 Q16637 3/20 0.58
▸ TTR P02766 3/20 0.58
▸ CYP19A1 P11511 3/20 0.53
▸ CA12 O43570 2/20 0.53
▸ CA1 P00915 2/20 0.53
▸ CA2 P00918 2/20 0.53
▸ CA3 P07451 2/20 0.53
▸ CA4 P22748 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2519163 0.94 MEN1 (0.64) PTGS2PTGS1KDM4ELMNACYP1A1
SCHEMBL2517137 0.88 TTR (0.75) PTGS2PTGS1KDM4ELMNACYP1A1
SCHEMBL2515226 0.87 PTGS2 (0.61) PTGS2PTGS1KDM4ELMNACYP1A1
SCHEMBL2574064 0.86 LMNA (0.77) PTGS2PTGS1KDM4ELMNACYP1A1
SCHEMBL2574065 0.86 LMNA (0.77) PTGS2PTGS1KDM4ELMNACYP1A1
SCHEMBL2521934 0.85 TTR (0.61) PTGS2PTGS1KDM4ELMNACYP1A1
Resveratrol SCHEMBL28375834 0.80 PTGS1 (0.76) PTGS2PTGS1KDM4ELMNACYP1A1
SCHEMBL18383806 0.80 KMT2A (0.56) PTGS2PTGS1KDM4ELMNACYP1A1
SCHEMBL1808386 0.80 MEN1 (0.84) PTGS2PTGS1KDM4ELMNACYP1A1
SCHEMBL1808387 0.80 MEN1 (0.84) PTGS2PTGS1KDM4ELMNACYP1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9861564-B2 Valeric acid esters of resveratrol and cosmetic compositions ELC MANAGEMENT, LLC (US) 2018-01-09 — — US disclosed
US-9782335-B2 Malic acid esters of resveratrol and cosmetic compositions ELC MANAGEMENT LLC (US) 2017-10-10 — — US disclosed
US-20160303016-A1 Valeric Acid Esters Of Resveratrol And Cosmetic Compositions ELC MAN LLC (US) 2016-10-20 — — US disclosed
EP-2445511-B1 SKIN REPAIR COMPOSITIONS COMPRISING CIRCADIAN GENE ACTIVATORS AND A SYNERGISTIC COMBINATION OF SIRT1 GENE ACTIVATORS ELC MAN LLC (US) 2016-09-07 — — EP disclosed
US-20160229791-A1 Malic Acid Esters Of Resveratrol And Cosmetic Compositions ELC MAN LLC (US) 2016-08-11 — — US disclosed
US-9358194-B2 Succinic acid esters of resveratrol and cosmetic compositions ELC MANAGEMENT LLC (US) 2016-06-07 — — US disclosed
US-9295621-B2 Emulsion cosmetic compositions containing resveratrol derivatives and silicone surfactant ELC MANAGEMENT LLC (US) 2016-03-29 — — US disclosed
US-20160038389-A1 Succinic Acid Esters Of Resveratrol And Cosmetic Compositions ELC MAN LLC (US) 2016-02-11 — — US disclosed
US-9180316-B2 Butyric acid esters of resveratrol and cosmetic compositions ELC MANAGEMENT LLC (US) 2015-11-10 — — US disclosed
US-9162083-B2 Linoleic and Linolenic acid esters of resveratrol and cosmetic compositions ELC MANAGEMENT LLC (US) 2015-10-20 — — US disclosed
US-8084496-B2 Resveratrol ferulate compounds and compositions ELC MANAGEMENT LLC (US) 2011-12-27 — — US disclosed
US-20110250251-A1 Cosmetic Methods And Compositions For Repairing Human Skin MAES DANIEL H 2011-10-13 — — US disclosed
US-20100216879-A1 Resveratrol Ferulate Compounds And Compositions MAES DANIEL H 2010-08-26 — — US disclosed
US-20100080845-A1 Cosmetic Methods And Compositions For Repairing Human Skin MAES DANIEL H 2010-04-01 — — US disclosed
US-20090047309-A1 COSMETIC METHODS AND COMPOSITIONS FOR REPAIRING HUMAN SKIN ELC MANAGEMENT LLC 2009-02-19 — — US disclosed
US-20090035243-A1 Anhydrous Cosmetic Compositions Containing Resveratrol Derivatives ELC MANAGEMENT LLC 2009-02-05 — — US disclosed
US-20090035240-A1 Aqueous Based Cosmetic Compositions Containing Resveratrol Derivatives And An Aqueous Phase Structuring Agent ELC MANAGEMENT LLC 2009-02-05 — — US disclosed
US-20090035242-A1 Emulsion Cosmetic Compositions Containing Resveratrol Derivatives And Linear Or Branched Silicone ELC MANAGEMENT LLC 2009-02-05 — — US disclosed
US-20090035237-A1 Emulsion Cosmetic Compositions Containing Resveratrol Derivatives And Silicone Surfactant ELC MANAGEMENT LLC 2009-02-05 — — US disclosed
US-20090035236-A1 Emulsion Cosmetic Compositions Containing Resveratrol Derivatives And An Oil Phase Structuring Agent ELC MANAGEMENT LLC 2009-02-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090035243-A1 Anhydrous Cosmetic Compositions Containing Resveratrol Derivatives RB1, SIRT1, EP300 PTGS2 3838/4885PTGS1 3215/4885KDM4E 506/4885
US-20090035242-A1 Emulsion Cosmetic Compositions Containing Resveratrol Derivatives And Linear Or Branched Silicone SQLE, SMURF1, PIK3R1 PTGS2 3228/4885PTGS1 2865/4885KDM4E 1188/4885
US-20100216879-A1 Resveratrol Ferulate Compounds And Compositions FER, FOLR1, FOLR2 PTGS2 2446/4885PTGS1 1735/4885KDM4E 1158/4885
US-20090047309-A1 COSMETIC METHODS AND COMPOSITIONS FOR REPAIRING HUMAN SKIN CUTA, ERCC1, OGG1 PTGS2 3235/4885PTGS1 2179/4885KDM4E 1584/4885
US-20110250251-A1 Cosmetic Methods And Compositions For Repairing Human Skin CUTA, ERCC1, OGG1 PTGS2 3235/4885PTGS1 2179/4885KDM4E 1584/4885
US-20160303016-A1 Valeric Acid Esters Of Resveratrol And Cosmetic Compositions CUTA, SUV39H1, RARA PTGS2 2796/4885PTGS1 2111/4885KDM4E 450/4885
US-20090035237-A1 Emulsion Cosmetic Compositions Containing Resveratrol Derivatives And Silicone Surfactant SMURF1, CUTA, SMURF2 PTGS2 3901/4885PTGS1 3381/4885KDM4E 1074/4885
US-20090035236-A1 Emulsion Cosmetic Compositions Containing Resveratrol Derivatives And An Oil Phase Structuring Agent CUTA, LRAT, RARA PTGS2 2396/4885PTGS1 2344/4885KDM4E 1813/4885
US-20090035240-A1 Aqueous Based Cosmetic Compositions Containing Resveratrol Derivatives And An Aqueous Phase Structuring Agent SMARCC1, RARG, RARA PTGS2 3031/4885PTGS1 2412/4885KDM4E 2286/4885
US-20100080845-A1 Cosmetic Methods And Compositions For Repairing Human Skin CUTA, ERCC1, OGG1 PTGS2 3235/4885PTGS1 2179/4885KDM4E 1584/4885
US-20160229791-A1 Malic Acid Esters Of Resveratrol And Cosmetic Compositions ME1, ME2, ME3 PTGS2 2574/4885PTGS1 1938/4885KDM4E 421/4885
US-20160038389-A1 Succinic Acid Esters Of Resveratrol And Cosmetic Compositions SUCNR1, SIRT1, SUCLA2 PTGS2 1728/4885PTGS1 1360/4885KDM4E 368/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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