SCHEMBL26017268

SCHEMBL26017268

Cc1cc(C(F)(F)F)c(-c2cc(-c3ccc(C)c(C)c3)ccc2C)c(C(F)(F)F)c1

nearest known ligand 0.37

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ AR P10275 3/20 0.37
▸ TRPA1 O75762 1/20 0.34
▸ NOTUM Q6P988 1/20 0.33
▸ PTGS2 P35354 4/20 0.33
▸ RXRA P19793 1/20 0.33
▸ RXRB P28702 1/20 0.33
▸ MCL1 Q07820 1/20 0.33
▸ S1PR1 P21453 2/20 0.32
▸ AKR1C3 P42330 1/20 0.32
▸ AKR1C2 P52895 1/20 0.32
▸ PTGS1 P23219 2/20 0.32
▸ RAPGEF4 Q8WZA2 1/20 0.32
▸ PDK2 Q15119 1/20 0.32
▸ ALPL P05186 1/20 0.32
▸ ALPI P09923 1/20 0.32
▸ CTSS P25774 1/20 0.32
▸ CTSK P43235 1/20 0.32
▸ TP53 P04637 1/20 0.32
▸ MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26532565 0.89 RXRA (0.41) ARTRPA1NOTUMPTGS2RXRA
SCHEMBL5936705 0.76 NOTUM (0.49) ARNOTUMRXRARXRBMCL1
SCHEMBL26017262 0.75 RXRA (0.44) NOTUMPTGS2RXRARXRBMCL1
SCHEMBL5936706 0.74 NOTUM (0.47) ARNOTUMRXRARXRBS1PR1
SCHEMBL26532925 0.74 ALOX5AP (0.39) ARNOTUMRXRARXRBS1PR1
SCHEMBL26532921 0.74 KIF11 (0.45) NOTUMPTGS2RXRARXRBTP53
SCHEMBL26017271 0.73 S1PR1 (0.43) ARTRPA1MCL1S1PR1TP53
SCHEMBL28147440 0.73 AR (0.41) ARTRPA1NOTUMPTGS2S1PR1
SCHEMBL26017265 0.73 PTGS2 (0.42) NOTUMPTGS2MCL1PTGS1MAPT
SCHEMBL26532922 0.72 RXRB (0.51) NOTUMPTGS2RXRARXRBMCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240218004-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-07-04 — — US disclosed
US-20240224782-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-07-04 — — US disclosed
US-20240209013-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-06-27 — — US disclosed
US-20230371358-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-16 — — US disclosed
US-20230365606-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-16 — — US disclosed
US-20230357296-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-09 — — US disclosed
US-20230348510-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-02 — — US disclosed
US-20230348509-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-02 — — US disclosed
US-20230337519-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 — — US disclosed
US-20230337521-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 — — US disclosed
US-20230337522-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 — — US disclosed
US-20230263049-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-08-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230337522-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES L1CAM, EML4, LBR AR 1923/4885TRPA1 469/4885NOTUM 4371/4885
US-20230357296-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OPRD1, OXER1, LBR AR 402/4885TRPA1 1268/4885NOTUM 3080/4885
US-20230337521-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, NR1H2 AR 175/4885TRPA1 373/4885NOTUM 3688/4885
US-20240209013-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, SSB, L1CAM AR 949/4885TRPA1 817/4885NOTUM 3893/4885
US-20230263049-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OSBPL3, OCIAD1, OSBP AR 698/4885TRPA1 95/4885NOTUM 1647/4885
US-20230348510-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LBR, OXER1, OXSR1 AR 294/4885TRPA1 1363/4885NOTUM 4481/4885
US-20230348509-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES MLX, OCIAD1, LBR AR 506/4885TRPA1 536/4885NOTUM 3986/4885
US-20230337519-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES SSB, YBX3, LBR AR 989/4885TRPA1 1632/4885NOTUM 4721/4885
US-20230371358-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIFR, SOD1, ROS1 AR 455/4885TRPA1 1686/4885NOTUM 4781/4885
US-20230365606-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OXER1, OPRD1, OXSR1 AR 350/4885TRPA1 1388/4885NOTUM 4135/4885
US-20240224782-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES RER1, OCIAD2, OCIAD1 AR 335/4885TRPA1 1204/4885NOTUM 4272/4885
US-20240218004-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, CCND2 AR 946/4885TRPA1 380/4885NOTUM 3442/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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