Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.34 |
| ▸ | NPC1 | O15118 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | HTT | P42858 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17823701 | 0.83 | ALDH1A1 (0.48) | ALDH1A1CA1CA2CA4CA5A | |
| SCHEMBL19962274 | 0.83 | ALDH1A1 (0.48) | ALDH1A1CA1CA2CA4CA5A | |
| Hydrochloric Acid SCHEMBL28484958 | 0.81 | ALDH1A1 (0.47) | ALDH1A1CA1CA2CA4CA5A | |
| Hydrochloric Acid SCHEMBL17823608 | 0.81 | ALDH1A1 (0.47) | ALDH1A1CA1CA2CA4CA5A | |
| SCHEMBL2631500 | 0.79 | CA1 (0.37) | ALDH1A1CA1CA2CA4CA5A | |
| SCHEMBL23048580 | 0.77 | SMN1; SMN2 (0.38) | ALDH1A1SMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL23916573 | 0.76 | SMN1; SMN2 (0.32) | ALDH1A1SMN1; SMN2NPC1RAB9ACYP1A2 | |
| SCHEMBL31339479 | 0.74 | ALDH1A1 (0.65) | ALDH1A1CA1CA2CA4CA5A | |
| SCHEMBL1106504 | 0.74 | SMN1; SMN2 (0.41) | ALDH1A1SMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL23741102 | 0.74 | SMN1; SMN2 (0.34) | ALDH1A1SMN1; SMN2NPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024044778-A2 | NOVEL MODULATORS OF FSHR AND USES THEREOF | CELMATIX INC. (US) | 2024-02-29 | — | — | WO | disclosed |
| US-20230158025-A1 | GALACTOKINASE INHIBITORS | NATIONAL INSTITUTES OF HEALTH | 2023-05-25 | — | — | US | disclosed |
| US-20230157287-A1 | PESTICIDAL COMPOUNDS | BASF SE (DE) | 2023-05-25 | — | — | US | disclosed |
| US-20230158025-A1 | GALACTOKINASE INHIBITORS | NATIONAL INSTITUTES OF HEALTH | 2023-05-25 | — | — | US | disclosed |
| EP-3601231-B1 | PESTICIDAL COMPOUNDS | BASF SE (DE) | 2023-05-10 | — | — | EP | disclosed |
| US-20220002284-A1 | PESTICIDAL COMPOUNDS | BASF SE (DE) | 2022-01-06 | — | — | US | disclosed |
| US-11160280-B2 | Pesticial compounds | BASF SE (DE) | 2021-11-02 | — | — | US | disclosed |
| US-11091464-B2 | Pyridazinone compounds and uses thereof | EDGEWISE THERAPEUTICS, INC. (US) | 2021-08-17 | — | — | US | disclosed |
| US-20210188860-A1 | 3-((Hetero-)Aryl)-8-Amino-2-Oxo-1,3-Diaza-Spiro-[4.5]-Decane Derivatives | Grünenthal GmbH (DE) | 2021-06-24 | — | — | US | disclosed |
| US-20210070713-A1 | PESTICIDAL COMPOUNDS | BASF SE (DE) | 2021-03-11 | — | — | US | disclosed |
| US-7790770-B2 | Heterocyclic CETP inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-09-07 | — | — | US | disclosed |
| US-20100130486-A1 | CYCLIC AMINE SUBSTITUTED PYRIMIDINEDIAMINES AS PKC INHIBITORS | RIGEL PHARMACEUTICALS, INC. | 2010-05-27 | — | — | US | disclosed |
| US-20100130486-A1 | CYCLIC AMINE SUBSTITUTED PYRIMIDINEDIAMINES AS PKC INHIBITORS | RIGEL PHARMACEUTICALS, INC. | 2010-05-27 | — | — | US | disclosed |
| US-20100063088-A1 | Raf Kinase Inhibitors | WOOD JILL E | 2010-03-11 | — | — | US | disclosed |
| US-20090239830-A1 | Treatment of viral infections by modulation of host cell metabolic pathways | KADMON CORPORATION, LLC | 2009-09-24 | — | — | US | disclosed |
| US-20090151779-A1 | Redox Couples, Compositions and Uses Thereof | DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) | 2009-06-18 | — | — | US | disclosed |
| US-7388021-B2 | Urea antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions | BRISTOL MYERS SQUIBB COMPANY (US) | 2008-06-17 | — | — | US | disclosed |
| US-20080041438-A1 | Photoelectric conversion device | DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) | 2008-02-21 | — | — | US | disclosed |
| US-20070161685-A1 | HETEROCYCLIC CETP INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2007-07-12 | — | — | US | disclosed |
| US-20070135631-A1 | HETEROCYCLIC CETP INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2007-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070161685-A1 | HETEROCYCLIC CETP INHIBITORS | CETP, CES1, NPC1 | ALDH1A1 2353/4885CA1 4507/4885CA2 3976/4885 |
| US-20100063088-A1 | Raf Kinase Inhibitors | BRAF, RAF1, ARAF | ALDH1A1 2732/4885CA1 3863/4885CA2 3646/4885 |
| US-20070135631-A1 | HETEROCYCLIC CETP INHIBITORS | CETP, CES1, NPC1 | ALDH1A1 2353/4885CA1 4507/4885CA2 3976/4885 |
| US-20090239830-A1 | Treatment of viral infections by modulation of host cell metabolic pathways | GOT2, MAVS, ME3 | ALDH1A1 1469/4885CA1 4668/4885CA2 4167/4885 |
| US-11160280-B2 | Pesticial compounds | PNMT, DDT, NIT2 | ALDH1A1 1844/4885CA1 1010/4885CA2 530/4885 |
| US-20230158025-A1 | GALACTOKINASE INHIBITORS | GALK1, GCK, GCKR | ALDH1A1 3139/4885CA1 2710/4885CA2 2327/4885 |
| US-20230157287-A1 | PESTICIDAL COMPOUNDS | PNMT, CAT, DDT | ALDH1A1 1917/4885CA1 1357/4885CA2 793/4885 |
| US-20100130486-A1 | CYCLIC AMINE SUBSTITUTED PYRIMIDINEDIAMINES AS PKC INHIBITORS | PRKCH, PKD2, PRKCQ | ALDH1A1 3843/4885CA1 4786/4885CA2 2202/4885 |
| US-20220002284-A1 | PESTICIDAL COMPOUNDS | NIT2, PNMT, THOP1 | ALDH1A1 1528/4885CA1 1512/4885CA2 752/4885 |
| US-20210070713-A1 | PESTICIDAL COMPOUNDS | CAT, NIT2, PNMT | ALDH1A1 1368/4885CA1 1434/4885CA2 868/4885 |
| US-11091464-B2 | Pyridazinone compounds and uses thereof | IL6, IL1B, IL1A | ALDH1A1 270/4885CA1 4879/4885CA2 4866/4885 |
| US-20210188860-A1 | 3-((Hetero-)Aryl)-8-Amino-2-Oxo-1,3-Diaza-Spiro-[4.5]-Decane Derivatives | OPRK1, OPRD1, OPRL1 | ALDH1A1 337/4885CA1 4166/4885CA2 2068/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.