SCHEMBL26271

SCHEMBL26271

CC(C)(C)OC(=O)N[C@@H](Cc1ccc(Br)cc1)C(=O)O

nearest known ligand 0.72

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CTSS P25774 7/20 0.72
CTSK P43235 6/20 0.72
ACE P12821 1/20 0.62
ITGB3 P05106 2/20 0.62
ITGA2B P08514 2/20 0.62
CTSB P07858 2/20 0.55
CTSL P07711 1/20 0.55
PPARA Q07869 5/20 0.54
PPARG P37231 4/20 0.54
ITGA4 P13612 1/20 0.53
ITGB7 P26010 1/20 0.53
PTPN1 P18031 2/20 0.53
PPARD Q03181 2/20 0.52
ITGB1 P05556 1/20 0.52
ITGAV P06756 1/20 0.52
ITGB5 P18084 1/20 0.52
FPR2 P25090 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL763600 1.00 CTSS (0.72) CTSSCTSKACEITGB3ITGA2B
SCHEMBL26270 1.00 CTSS (0.72) CTSSCTSKACEITGB3ITGA2B
SCHEMBL21447323 0.89 CTSS (0.69) CTSSCTSKACEITGB3ITGA2B
SCHEMBL16448051 0.89 ACE (0.62) CTSSCTSKACEITGB3ITGA2B
SCHEMBL25532536 0.89 CTSS (0.68) CTSSCTSKACEITGB3ITGA2B
SCHEMBL5887611 0.89 CTSS (0.68) CTSSCTSKACEITGB3ITGA2B
SCHEMBL5887609 0.89 CTSS (0.68) CTSSCTSKACEITGB3ITGA2B
SCHEMBL11728465 0.89 CTSS (0.61) CTSSCTSKACEITGB3ITGA2B
SCHEMBL2617401 0.88 CTSS (0.67) CTSSCTSKACEITGB3ITGA2B
SCHEMBL539218 0.88 CTSS (0.67) CTSSCTSKACEITGB3ITGA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 498 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112574245-A 4-10Preparation method of boric acid group-L-phenylalanine 四川瑶天纳米科技有限责任公司 2021-03-30 CN claimed
WO-2026107097-A1 SELF-IMMOLATIVE LINKERS AND CONJUGATES THEREOF ENLAZA THERAPEUTICS, INC. (US) 2026-05-21 WO disclosed
US-12630808-B2 Modified archaeal family b polymerases Singular Genomics Systems, Inc. (US) 2026-05-19 US disclosed
US-20260125660-A1 MODIFIED ARCHAEAL FAMILY B POLYMERASES SINGULAR GENOMICS SYSTEMS INC (US) 2026-05-07 US disclosed
US-20260117274-A1 ORTHOGONALLY CROSSLINKED PROTEINS, METHODS OF MAKING, AND USES THEREOF UNIV NEW YORK STATE RES FOUND (US) 2026-04-30 US disclosed
US-20260116923-A1 CYCLIC PEPTIDE IL-1BETA TRAP FOR THE TREATMENT OF ATHEROSCLEROSIS AND INFLAMMATORY DISORDERS MERCK SHARP & DOHME LLC (US) 2026-04-30 US disclosed
EP-4540267-B1 CYCLIC PEPTIDES FOR TRAPPING INTERLEUKIN-1 BETA MERCK SHARP & DOHME LLC (US) 2026-04-15 EP disclosed
US-20260091017-A1 TREATMENTS FOR INFLAMMATION AUCKLAND UNISERVICES LTD (NZ) 2026-04-02 US disclosed
US-20260085299-A1 ENGINEERED PYROCOCCUS ENZYMES AND USES THEREOF SINGULAR GENOMICS SYSTEMS INC (US) 2026-03-26 US disclosed
US-12564644-B2 Cyclodextrin complexes of specialized proresolving mediators THETIS PHARMACEUTICALS LLC (US) 2026-03-03 US disclosed
EP-1150565-A1 THIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF LION bioscience AG (DE) 2001-11-07 EP disclosed
CN-1288457-A Inhibitors of & alpha, 4 mediated cell adhesion TANABE SEIYAKU CO (JP) 2001-03-21 CN disclosed
WO-2000045635-A1 THIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF LION BIOSCIENCE AG (DE) 2000-08-10 WO disclosed
EP-0991619-A1 INHIBITORS OF $g(a) 4?$g(b) 1?MEDIATED CELL ADHESION TANABE SEIYAKU CO., LTD. (JP) 2000-04-12 EP disclosed
US-6008240-A AN ANTAGONIST OF HISTAMINE H3 RECEPTORS; FOR TREATING ALLERGY, INFLAMMATION, CARDIOVASCULAR DISEASE (HYPER OR HYPOTENSION), GASTROINTESTINAL DISORDERS, CNS DISORDERS INVOLVING ATTENTION OR COGNITIVE DISORDERS GLIATECH, INC. (US) 1999-12-28 US disclosed
WO-1998058902-A1 INHIBITORS OF α4β1MEDIATED CELL ADHESION TANABE SEIYAKU CO., LTD. (JP) 1998-12-30 WO disclosed
EP-0041286-B1 LH-RH ANTAGONISTS Schally, Andrew Victor (US) 1984-08-15 EP disclosed
US-4431635-A PEPTIDE ANALOGS OF LUTEINIZING HORMONE RELEASING HORMONE; GLANDULAR DISORDERS; ANTICARCINOGENIC AGENTS COY DAVID HOWARD 1984-02-14 US disclosed
US-4317815-A PEPTIDE ANALOGS OF LUTENIZING HORMONE RELEASING HORMONE ADMINISTRATORS OF THE TULANE UNIVERSITY EDUCATIONAL FUND, THE, A CORPORATE ENTITY OF TULANE UNIVERSITY A CORP. OF LA. 1982-03-02 US disclosed
EP-0041286-A1 LH-RH antagonists Schally, Andrew Victor (US) 1981-12-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260091017-A1 TREATMENTS FOR INFLAMMATION P2RX7, NLRP3, PYCARD CTSS 614/4885CTSK 583/4885ACE 3545/4885
US-12630808-B2 Modified archaeal family b polymerases SSU72, POLB, POLQ CTSS 3439/4885CTSK 3867/4885ACE 1258/4885
US-20260117274-A1 ORTHOGONALLY CROSSLINKED PROTEINS, METHODS OF MAKING, AND USES THEREOF PTMS, PSMG3, PSMB3 CTSS 3065/4885CTSK 3616/4885ACE 1510/4885
US-20260116923-A1 CYCLIC PEPTIDE IL-1BETA TRAP FOR THE TREATMENT OF ATHEROSCLEROSIS AND INFLAMMATORY DISORDERS IL1A, IL1B, IL1RN CTSS 565/4885CTSK 868/4885ACE 3189/4885
US-20260085299-A1 ENGINEERED PYROCOCCUS ENZYMES AND USES THEREOF POLB, POLM, POLRMT CTSS 1137/4885CTSK 2422/4885ACE 565/4885
US-20260125660-A1 MODIFIED ARCHAEAL FAMILY B POLYMERASES DNMT3A, POLB, POLM CTSS 2859/4885CTSK 3873/4885ACE 663/4885
US-12564644-B2 Cyclodextrin complexes of specialized proresolving mediators ALOX15, ALOX12, PTGES CTSS 823/4885CTSK 2120/4885ACE 3413/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.