SCHEMBL2800851

SCHEMBL2800851

CCCCCCc1c(ON(CC)CC)cccc1C(=O)OC(=O)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 2/20 0.39
LMNA P02545 4/20 0.39
TSHR P16473 2/20 0.39
ALDH1A1 P00352 2/20 0.39
MAPT P10636 2/20 0.38
CYP3A4 P08684 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
NR1I2 O75469 1/20 0.38
CHRM2 P08172 1/20 0.38
ADRA2A P08913 1/20 0.38
OPRK1 P41145 1/20 0.38
HTR2B P41595 1/20 0.38
SLC6A3 Q01959 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
PPARG P37231 1/20 0.37
TP53 P04637 1/20 0.36
MAPK1 P28482 1/20 0.36
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28528772 0.82 SLC6A3 (0.48) LMNATSHRALDH1A1MAPTMEN1
SCHEMBL28356343 0.79 THRA (0.46) PPARALMNATSHRALDH1A1MAPT
SCHEMBL28790813 0.76 PTPN1 (0.41) PPARALMNATSHRALDH1A1CYP3A4
SCHEMBL1790208 0.76 TSHR (0.48) PPARALMNATSHRALDH1A1CYP3A4
SCHEMBL28821059 0.76 PPARA (0.44) PPARALMNATSHRALDH1A1MAPT
SCHEMBL27509767 0.74 LMNA (0.63) LMNATSHRALDH1A1MAPTCYP3A4
SCHEMBL29044418 0.74 ALDH1A1 (0.40) PPARALMNATSHRALDH1A1MAPT
SCHEMBL27934134 0.74 TSHR (0.46) PPARALMNATSHRALDH1A1CYP3A4
SCHEMBL28167194 0.74 KAT8 (0.43) PPARALMNATSHRALDH1A1PPARG
SCHEMBL995525 0.73 ALDH1A1 (0.56) PPARALMNATSHRALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3847577-A1 A METHOD AND SYSTEM FOR COSMETIC RECOMMENDATIONS Skin Rejuvenation Technologies (Pty) Ltd. (ZA) 2021-07-14 EP disclosed
WO-2020016775-A1 A METHOD AND SYSTEM FOR COSMETIC RECOMMENDATIONS SKIN REJUVENTATION TECHNOLOGIES (PTY) LTD (ZA) 2020-01-23 WO disclosed
WO-2018144796-A1 SUNSCREEN COMPOSITIONS WITH NATURAL WAXES FOR IMPROVED WATER RESISTANCE EDGEWELL PERSONAL CARE BRANDS, LLC (US) 2018-08-09 WO disclosed
US-9657228-B2 Performance boosting UV-absorbing compounds ISP INVESTMENTS LLC (US) 2017-05-23 US disclosed
US-9289631-B2 Polymer-bound UV absorbers in personal care compositions ISP INVESTMENTS INC. (US) 2016-03-22 US disclosed
US-20150265522-A1 POLYMER-BOUND UV ABSORBERS IN PERSONAL CARE COMPOSITIONS ISP INVESTMENTS INC. (US) 2015-09-24 US disclosed
US-9044623-B2 Polymer-bound UV absorbers in personal care compositions ISP INVESTMENTS INC. (US) 2015-06-02 US disclosed
US-20140023601-A1 PERFORMANCE BOOSTING UV-ABSORBING COMPOUNDS ISP INVESTMENT INC. (US) 2014-01-23 US disclosed
US-20130309185-A1 COMPOSITIONS COMPRISING STABILIZED KETO- ENOL UV ABSORBERS ISP INVESTMENTS INC. 2013-11-21 US disclosed
US-8557226-B2 Performance-boosting UV-absorbing compounds ISP INVESTMENTS INC. (US) 2013-10-15 US disclosed
WO-2012078961-A1 COMPOSITIONS COMPRISING STABILIZED KETO-ENOL UV ABSORBERS ISP INVESTMENT INS. (US) 2012-06-14 WO disclosed
US-20100189661-A1 POLYMER-BOUND UV ABSORBERS IN PERSONAL CARE COMPOSITIONS PHARMACHEM LABORATORIES LLC 2010-07-29 US disclosed
US-20100183532-A1 Performance-Boosting UV-Absorbing Compounds HERCULES LLC 2010-07-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100189661-A1 POLYMER-BOUND UV ABSORBERS IN PERSONAL CARE COMPOSITIONS CUTA, UACA, LAGE3 PPARA 3103/4885LMNA 33/4885TSHR 1383/4885
US-20130309185-A1 COMPOSITIONS COMPRISING STABILIZED KETO- ENOL UV ABSORBERS SDHB, CUTA, ALAD PPARA 2239/4885LMNA 2223/4885TSHR 4293/4885
US-20100183532-A1 Performance-Boosting UV-Absorbing Compounds APOB, ALOX5, RARG PPARA 170/4885LMNA 2251/4885TSHR 2516/4885
US-20150265522-A1 POLYMER-BOUND UV ABSORBERS IN PERSONAL CARE COMPOSITIONS CUTA, UACA, LAGE3 PPARA 3103/4885LMNA 33/4885TSHR 1383/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.