Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 known ✓ | O43570 | 3/20 | 0.39 |
| ▸ | CA2 known ✓ | P00918 | 3/20 | 0.39 |
| ▸ | GABBR2 known ✓ | O75899 | 2/20 | 0.34 |
| ▸ | GABBR1 known ✓ | Q9UBS5 | 2/20 | 0.34 |
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28363012 | 0.78 | GABBR2 (0.49) | CCR5GABBR2GABBR1CYP2C19NPSR1 | |
| SCHEMBL5598365 | 0.75 | TSHR (0.48) | GABBR2GABBR1NPSR1CYP1A2CYP2D6 | |
| SCHEMBL10638205 | 0.73 | LMNA (0.47) | CA12CA2CA9CYP2C19PKM | |
| SCHEMBL4760112 | 0.69 | MTNR1A (0.60) | — | |
| SCHEMBL2237751 | 0.67 | LMNA (0.48) | CCR5CYP2D6TSHRLMNA | |
| SCHEMBL28576347 | 0.67 | TRPA1 (0.42) | GABBR2GABBR1NPSR1CYP1A2CYP2D6 | |
| SCHEMBL8032906 | 0.67 | TRPA1 (0.42) | GABBR2GABBR1NPSR1CYP1A2CYP2D6 | |
| Sulfuric Acid SCHEMBL6557209 | 0.67 | TSHR (0.67) | CA12CA2CA9CYP2C19CYP2D6 | |
| SCHEMBL27882751 | 0.67 | GABBR2 (0.37) | GABBR2GABBR1NPSR1CYP1A2CYP2D6 | |
| SCHEMBL4175640 | 0.67 | GABBR2 (0.66) | GABBR2GABBR1CYP2C19NPSR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110835522-B | Temperature-resistant and salt-resistant type super-thick oil emulsifying viscosity reducer and preparation method thereof | 中国石油化工股份有限公司 | 2022-02-15 | — | — | CN | claimed |
| CN-110835522-A | Temperature-resistant and salt-resistant type super-thick oil emulsifying viscosity reducer and preparation method thereof | 中国石油化工股份有限公司 | 2020-02-25 | — | — | CN | claimed |
| CN-110835522-B | Temperature-resistant and salt-resistant type super-thick oil emulsifying viscosity reducer and preparation method thereof | 中国石油化工股份有限公司 | 2022-02-15 | — | — | CN | disclosed |
| CN-110835522-A | Temperature-resistant and salt-resistant type super-thick oil emulsifying viscosity reducer and preparation method thereof | 中国石油化工股份有限公司 | 2020-02-25 | — | — | CN | disclosed |