SCHEMBL2846646

SCHEMBL2846646

Clc1ccccc1-c1ccccc1Br

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 2/20 0.55
ALDH1A1 P00352 3/20 0.50
CYP2A6 P11509 1/20 0.50
MAPK1 P28482 1/20 0.50
DPP4 P27487 1/20 0.46
LMNA P02545 2/20 0.45
TSHR P16473 1/20 0.45
NPC1 O15118 3/20 0.43
RAB9A P51151 3/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
HPGD P15428 2/20 0.43
TP53 P04637 1/20 0.43
PTPRC P08575 1/20 0.42
ELANE P08246 1/20 0.41
MAOB P27338 2/20 0.41
POLB P06746 1/20 0.41
KMT2A Q03164 1/20 0.41
PLA2G7 Q13093 1/20 0.41
TAAR1 Q96RJ0 2/20 0.39
IDO1 P14902 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30097499 1.00 HSD11B1 (0.55) HSD11B1ALDH1A1CYP2A6MAPK1DPP4
SCHEMBL10664062 1.00 HSD11B1 (0.55) HSD11B1ALDH1A1CYP2A6MAPK1DPP4
SCHEMBL19501161 0.97 HSD11B1 (0.53) HSD11B1ALDH1A1CYP2A6MAPK1DPP4
SCHEMBL28356286 0.83 HSD11B1 (0.46) HSD11B1ALDH1A1CYP2A6MAPK1DPP4
SCHEMBL20961072 0.83 HSD11B1 (0.46) HSD11B1ALDH1A1CYP2A6MAPK1LMNA
SCHEMBL358976 0.83 ALDH1A1 (0.67) HSD11B1ALDH1A1MAPK1LMNATSHR
SCHEMBL31295703 0.83 ALDH1A1 (0.67) HSD11B1ALDH1A1MAPK1LMNATSHR
SCHEMBL671133 0.83 CYP2A6 (0.67) HSD11B1ALDH1A1CYP2A6DPP4LMNA
SCHEMBL29802156 0.83 CYP2A6 (0.67) HSD11B1ALDH1A1CYP2A6DPP4LMNA
SCHEMBL29883244 0.83 CYP2A6 (0.67) HSD11B1ALDH1A1CYP2A6DPP4LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 168 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12552809-B2 Compound for organic electric element, organic electric element comprising the same, and electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2026-02-17 US disclosed
US-20260035339-A1 TETRAHYDRONAPHTHALENE DERIVATIVE ATRANSEN PHARMA LTD (JP) 2026-02-05 US disclosed
US-12527215-B2 Compound for organic electrical element, organic electrical element using same and electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2026-01-13 US disclosed
EP-3981762-B1 NITROGEN-CONTAINING COMPOUND, ELECTRONIC ELEMENT, AND ELECTRONIC DEVICE SHAANXI LIGHTE OPTOELECTRONICS MAT CO LTD (CN) 2025-10-15 EP disclosed
CN-116283725-B Aromatic amine substituted dibenzofive-membered ring compound and application thereof 烟台显华科技集团股份有限公司 2025-06-24 CN disclosed
WO-2025121854-A1 ORGANIC LIGHT-EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 솔루스첨단소재 주식회사 2025-06-12 WO disclosed
US-12289988-B2 Nitrogen-containing compounds, electronic elements and electronic devices SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2025-04-29 US disclosed
US-12274163-B2 Compound for organic electrical element, organic electrical element using same and electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2025-04-08 US disclosed
EP-4501906-A1 TETRAHYDRONAPHTHALENE DERIVATIVE Atransen Pharma Ltd. (JP) 2025-02-05 EP disclosed
US-12193321-B2 Compound for organic electric element, organic electric element comprising the same, and electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2025-01-07 US disclosed
US-20090264428-A1 Renin Inhibitors VITAE PHARMACEUTICALS, INC. 2009-10-22 US disclosed
WO-2009096996-A1 RENIN INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 2009-08-06 WO disclosed
US-20090018103-A1 Diaminoalkane Aspartic Protease Inhibitors VITAE PHARMACEUTICAL, INC (US) 2009-01-15 US disclosed
US-20090018103-A1 Diaminoalkane Aspartic Protease Inhibitors VITAE PHARMACEUTICAL, INC (US) 2009-01-15 US disclosed
WO-2008124575-A1 RENIN INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 2008-10-16 WO disclosed
WO-2008124577-A1 RENIN INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 2008-10-16 WO disclosed
WO-2008124582-A1 RENIN INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 2008-10-16 WO disclosed
WO-2007117482-A2 RENIN INHIBITORS VITAE PHARMACEUTICALS, INC. (US) 2007-10-18 WO disclosed
WO-2007117560-A2 PIPERIDINE AND MORPHOLINE RENIN INHIBITORS VITAE PHARMACEUTICALS, INC. (US) 2007-10-18 WO disclosed
WO-2006042150-A1 DIAMINOALKANE ASPARTIC PROTEASE INHIBITORS VITAE PHARMACEUTICALS, INC. (US) 2006-04-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12274163-B2 Compound for organic electrical element, organic electrical element using same and electronic device thereof PIEZO1, ASIC1, TMEM109 HSD11B1 2375/4885ALDH1A1 664/4885CYP2A6 1830/4885
US-12289988-B2 Nitrogen-containing compounds, electronic elements and electronic devices NPPA, NES, INA HSD11B1 4061/4885ALDH1A1 1874/4885CYP2A6 2392/4885
US-20090018103-A1 Diaminoalkane Aspartic Protease Inhibitors DNPEP, PEPD, ACE HSD11B1 2182/4885ALDH1A1 587/4885CYP2A6 2233/4885
US-12193321-B2 Compound for organic electric element, organic electric element comprising the same, and electronic device thereof PIEZO1, ORAI2, OR10J3 HSD11B1 2108/4885ALDH1A1 1135/4885CYP2A6 2433/4885
US-20260035339-A1 TETRAHYDRONAPHTHALENE DERIVATIVE LATS1, LATS2, BCAT1 HSD11B1 358/4885ALDH1A1 1267/4885CYP2A6 1376/4885
US-12552809-B2 Compound for organic electric element, organic electric element comprising the same, and electronic device thereof KCNE1, KCNN4, RER1 HSD11B1 1575/4885ALDH1A1 1374/4885CYP2A6 1063/4885
US-20090264428-A1 Renin Inhibitors REN, ACE, SERPINB1 HSD11B1 314/4885ALDH1A1 1060/4885CYP2A6 1479/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.