Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGF1 known ✓ | P05230 | 1/20 | 0.34 |
| ▸ | CA12 known ✓ | O43570 | 1/20 | 0.33 |
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.33 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | RHOA | P61586 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29869308 | 0.86 | THRB (0.34) | RECQLPARP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL1921217 | 0.86 | THRB (0.34) | RECQLPARP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL4950631 | 0.81 | — | — | |
| SCHEMBL21436488 | 0.80 | L3MBTL1 (0.31) | KMT2AMEN1POLB | |
| SCHEMBL5359195 | 0.79 | EIF2AK2 (0.34) | PARP1PTPN1LMNA | |
| SCHEMBL3624402 | 0.79 | LMNA (0.38) | ALDH1A1MAPTLMNA | |
| SCHEMBL2868621 | 0.77 | MAPT (0.37) | PARP1KMT2AMEN1MAPTPTPN1 | |
| SCHEMBL28997618 | 0.76 | THRB (0.35) | RECQLKMT2AMEN1RHOA | |
| SCHEMBL1639154 | 0.75 | PLCG1 (0.34) | — | |
| SCHEMBL29387249 | 0.75 | LMNA (0.35) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004013178-A1 | FUSION PROTEINS BETWEEN A FLUORESCENT PROTEIN AND AN IONOTROPIC RECEPTOR AND USES THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2004-02-12 | — | — | WO | claimed |
| EP-0986759-A2 | USE OF A FLUORESCENT PROTEIN FOR DETECTING INTERACTION BETWEEN A TARGET PROTEIN AND ITS LIGAND | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2000-03-22 | — | — | EP | claimed |
| WO-1998055873-A2 | USE OF A FLUORESCENT PROTEIN FOR DETECTING INTERACTION BETWEEN A TARGET PROTEIN AND ITS LIGAND | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 1998-12-10 | — | — | WO | claimed |
| WO-2022188373-A1 | METHOD FOR DETECTING WATER-SOLUBLE ANIONIC SYNTHETIC PIGMENT IN FOOD | 广州市食品检验所（广州市酒类检测中心） | 2022-09-15 | — | — | WO | disclosed |
| US-10589003-B2 | Methods for coating surfaces with antimicrobial agents | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2020-03-17 | — | — | US | disclosed |
| US-20180303977-A1 | METHODS FOR COATING SURFACES WITH ANTIMICROBIAL AGENTS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2018-10-25 | — | — | US | disclosed |
| US-7713472-B2 | Antiseptic derivatives with broad spectrum antimicrobial activity for the impregnation of surfaces | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2010-05-11 | — | — | US | disclosed |
| US-7651661-B2 | Medical devices with broad spectrum antimicrobial activity | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2010-01-26 | — | — | US | disclosed |
| US-20080183152-A1 | MEDICAL DEVICES WITH BROAD SPECTRUM ANTIMICROBIAL ACTIVITY | RAAD ISSAM | 2008-07-31 | — | — | US | disclosed |
| US-20070154621-A1 | METHODS FOR COATING SURFACES WITH ANTIMICROBIAL AGENTS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2007-07-05 | — | — | US | disclosed |
| US-7202046-B2 | interactions with the fluorescent ligand are then detected by means of the changes in the donor's and acceptor's excitation and/or emission energy spectra; ligands are defined as being pharmacologically significant if interaction with target protein is inhibited by the addition of non-fluorescent ligand | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2007-04-10 | — | — | US | disclosed |
| US-20060194259-A1 | Method for isolating an allosteric effector of a receptor | UNIVERSITE LOUIS PASTEUR DE STRASSOURG (FR) | 2006-08-31 | — | — | US | disclosed |
| EP-0986759-B1 | USE OF A FLUORESCENT PROTEIN FOR DETECTING THE INTERACTION BETWEEN A MEMBRANE RECEPTOR AND ITS LIGAND | CENTRE NAT RECH SCIENT (FR) | 2006-04-26 | — | — | EP | disclosed |
| US-20050197634-A1 | Methods for coating and impregnating medical devices with antiseptic compositions | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2005-09-08 | — | — | US | disclosed |
| US-20050059036-A1 | Use of a fluorescent protein for detecting interaction between a target protein and its ligand | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2005-03-17 | — | — | US | disclosed |
| EP-1514112-A2 | METHOD FOR ISOLATING AN ALLOSTERIC EFFECTOR OF A RECEPTOR | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2005-03-16 | — | — | EP | disclosed |
| WO-2004013178-A1 | FUSION PROTEINS BETWEEN A FLUORESCENT PROTEIN AND AN IONOTROPIC RECEPTOR AND USES THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2004-02-12 | — | — | WO | disclosed |
| WO-2003107004-A2 | METHOD FOR ISOLATING AN ALLOSTERIC EFFECTOR OF A RECEPTOR | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2003-12-24 | — | — | WO | disclosed |
| EP-0986759-A2 | USE OF A FLUORESCENT PROTEIN FOR DETECTING INTERACTION BETWEEN A TARGET PROTEIN AND ITS LIGAND | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2000-03-22 | — | — | EP | disclosed |
| WO-1998055873-A2 | USE OF A FLUORESCENT PROTEIN FOR DETECTING INTERACTION BETWEEN A TARGET PROTEIN AND ITS LIGAND | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 1998-12-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10589003-B2 | Methods for coating surfaces with antimicrobial agents | CUTA, CD63, CDC37 | FGF1 3465/4885CA12 1935/4885CA1 2772/4885 |
| US-20180303977-A1 | METHODS FOR COATING SURFACES WITH ANTIMICROBIAL AGENTS | CUTA, CD63, CDC37 | FGF1 3465/4885CA12 1935/4885CA1 2772/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.