SCHEMBL1639154

SCHEMBL1639154

O=C1C(S(=O)(=O)[O-])=Cc2cc(S(=O)(=O)[O-])ccc2/C1=N/Nc1cc(N=Nc2ccc(S(=O)(=O)[O-])cc2)ccc1S(=O)(=O)[O-].[Na+].[Na+].[Na+].[Na+]

nearest known ligand 0.34

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
THRB known ✓ P10828 1/20 0.33
PLCG1 P19174 1/20 0.34
SLC7A11 Q9UPY5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2868621 0.81 MAPT (0.37) PLCG1THRBSLC7A11
SCHEMBL1921217 0.80 THRB (0.34) THRB
SCHEMBL29869308 0.80 THRB (0.34) THRB
SCHEMBL5359195 0.80 EIF2AK2 (0.34)
SCHEMBL3624402 0.78 LMNA (0.38)
SCHEMBL2866129 0.75 RECQL (0.34)
SCHEMBL20512992 0.74 LMNA (0.40) PLCG1
SCHEMBL4950631 0.73
SCHEMBL29387249 0.73 LMNA (0.35)
SCHEMBL21436488 0.72 L3MBTL1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250361217-A1 FATTY ACID COMPOUNDS UNIV PITTSBURGH COMMONWEALTH SYS HIGHER EDUCATION (US) 2025-11-27 US disclosed
EP-4543842-A1 FATTY ACID COMPOUNDS UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2025-04-30 EP disclosed
CN-110501499-B Lateral flow reagent strip with indicator zone and method of making same 上海艾瑞德生物科技有限公司 2025-02-14 CN disclosed
WO-2023250486-A1 FATTY ACID COMPOUNDS UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2023-12-28 WO disclosed
CN-212031502-U Lateral flow reagent strip with indicating area and detection card comprising same 上海艾瑞德生物科技有限公司 2020-11-27 CN disclosed
US-10589003-B2 Methods for coating surfaces with antimicrobial agents THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2020-03-17 US disclosed
CN-110501499-A Effluent reagent strip with indicating area and preparation method thereof SHANGHAI I READER BIOLOGICAL TECH CO LTD 2019-11-26 CN disclosed
EP-2257807-B1 METHOD FOR DETECTING AND QUANTIFYING A MOLECULE INCLUDING AT LEAST ONE PROTON GROUP ON A SOLID SUBSTRATE CENTRE NAT ETD SPATIALES (FR) 2018-12-19 EP disclosed
US-20180303977-A1 METHODS FOR COATING SURFACES WITH ANTIMICROBIAL AGENTS THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2018-10-25 US disclosed
US-20180117084-A1 METHODS FOR ENHANCING AN IMMUNE RESPONSE WITH A CTLA-4 ANTAGONIST BAYLOR COLLEGE OF MEDICINE 2018-05-03 US disclosed
US-6863866-B2 Self-contained devices for detecting biological contaminants BIOCONTROL SYSTEMS, INC. (US) 2005-03-08 US disclosed
EP-1289659-B1 SELF-CONTAINED DEVICES FOR DETECTING BIOLOGICAL CONTAMINANTS BIOCONTROL SYSTEMS INC (US) 2005-01-26 EP disclosed
US-20030235512-A1 Detection of contaminants using self-contained devices employing target material binding dyes BIOCONTROL SYSTEMS, INC. 2003-12-25 US disclosed
US-6551834-B2 Sampler for collecting target material, sampler wash solution, signal generator comprising dye which binds to target material to signal presence of target material; testing for biological contamination BIOCONTROL SYSTEMS, INC. 2003-04-22 US disclosed
EP-1289659-A2 SELF-CONTAINED DEVICES FOR DETECTING BIOLOGICAL CONTAMINANTS BioControl Systems, Inc. (US) 2003-03-12 EP disclosed
US-20020057991-A1 Self-contained devices for detecting biological contaminants BIOCONTROL SYSTEM INC. 2002-05-16 US disclosed
WO-2001091903-A2 SELF-CONTAINED DEVICES FOR DETECTING BIOLOGICAL CONTAMINANTS BIOCONTROL SYSTEMS, INC. (US) 2001-12-06 WO disclosed
US-20010026942-A1 Detection of contaminants using self-contained devices employing target material binding dyes BIOCONTROL SYSTEMS, INC. 2001-10-04 US disclosed
EP-1104257-A1 DETECTION OF CONTAMINANTS USING SELF-CONTAINED DEVICES EMPLOYING TARGET MATERIAL BINDING DYES BioControl Systems, Inc. (US) 2001-06-06 EP disclosed
WO-2000009016-A1 DETECTION OF CONTAMINANTS USING SELF-CONTAINED DEVICES EMPLOYING TARGET MATERIAL BINDING DYES BIOCONTROL SYSTEMS, INC. (US) 2000-02-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10589003-B2 Methods for coating surfaces with antimicrobial agents CUTA, CD63, CDC37 THRB 4713/4885PLCG1 3351/4885SLC7A11 4501/4885
US-20250361217-A1 FATTY ACID COMPOUNDS FASN, FABP2, ELOVL1 THRB 3252/4885PLCG1 2398/4885SLC7A11 233/4885
US-20180303977-A1 METHODS FOR COATING SURFACES WITH ANTIMICROBIAL AGENTS CUTA, CD63, CDC37 THRB 4713/4885PLCG1 3351/4885SLC7A11 4501/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.