SCHEMBL2907058

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL11365313	0.88	KDM4E (0.49)	TTRMEN1KMT2ANPC1RAB9A
	SCHEMBL2907889	0.88	TTR (0.54)	TTRMEN1KMT2ANPC1RAB9A
	SCHEMBL2907061	0.87	TTR (0.53)	TTRMEN1KMT2ANPC1RAB9A
	SCHEMBL2907068	0.87	TTR (0.53)	TTRMEN1KMT2ANPC1RAB9A
	SCHEMBL2908306	0.83	TBK1 (0.57)	TTRNPC1RAB9AKDM4ETBK1
	SCHEMBL11108156	0.81	MAOB (0.56)	TTRMEN1KMT2ANPC1RAB9A
	SCHEMBL11356857	0.77	TTR (0.56)	TTRMEN1KMT2ANPC1RAB9A
	SCHEMBL11549501	0.76	MEN1 (0.70)	TTRMEN1KMT2ANPC1RAB9A
	SCHEMBL11375422	0.76	GPR35 (0.46)	TTRMEN1KMT2ANPC1RAB9A
	SCHEMBL11352938	0.75	KDM4E (0.48)	TTRMEN1KMT2ANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.