Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28493916 | 0.87 | USP2 (0.44) | USP2TSHRCA1CA2 | |
| SCHEMBL19196417 | 0.77 | KDM4E (0.46) | USP2TSHRCA1CA2 | |
| SCHEMBL15221739 | 0.73 | — | — | |
| SCHEMBL15221738 | 0.73 | — | — | |
| SCHEMBL12183673 | 0.71 | — | — | |
| SCHEMBL31278598 | 0.71 | — | — | |
| SCHEMBL22441900 | 0.71 | — | — | |
| SCHEMBL9574444 | 0.67 | USP2 (0.44) | USP2TSHRCA1CA2 | |
| SCHEMBL17319610 | 0.67 | — | — | |
| SCHEMBL4295035 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060085922-A1 | Oxidizing composition comprising at least one electrophilic monomer and at least one non-benzoquinone oxidant | L'OREAL S.A. (FR) | 2006-04-27 | — | — | US | claimed |
| US-20120156270-A1 | METHOD FOR SMOOTHING OUT THE SKIN BY FILLING IN RECESSED PORTIONS | L'OREAL (FR) | 2012-06-21 | — | — | US | disclosed |
| EP-2451536-A2 | METHOD FOR SMOOTHING OUT THE SKIN BY FILLING IN RECESSED PORTIONS | L'Oréal (FR) | 2012-05-16 | — | — | EP | disclosed |
| US-20100172858-A1 | COSMETIC COMPOSITION COMPRISING AT LEAST ONE POLYMER OBTAINED FROM A DIELECTROPHILIC MONOMER | L'OREAL S.A. (FR) | 2010-07-08 | — | — | US | disclosed |
| US-7621966-B2 | Cosmetic composition comprising at least one pigment and/or at least one filler surface-treated beforehand with at least one organic agent and at least one electrophilic monomer | L'OREAL S.A. (FR) | 2009-11-24 | — | — | US | disclosed |
| US-20080038218-A1 | Cosmetic composition comprising at least one electrophilic monomer, at least one fluoro compound and at least one liquid organic solvent | L'OREAL S.A. (FR) | 2008-02-14 | — | — | US | disclosed |
| US-20070251028-A1 | Dyeing composition comprising at least one electrophilic monomer, one hydrophilic dye and one liquid organic solvent | L'OREAL S.A. (FR) | 2007-11-01 | — | — | US | disclosed |
| US-20070251027-A1 | Dyeing composition comprising at least one soluble fluorescent compound, at least one electrophilic monomer and at least one liquid organic solvent | L'OREAL S.A. (FR) | 2007-11-01 | — | — | US | disclosed |
| US-20070253927-A1 | Cosmetic compositions comprising at least one dielectrophile monomer and at least one radical initiator | L'OREAL S.A. (FR) | 2007-11-01 | — | — | US | disclosed |
| WO-2007118812-A1 | COMPOSITION FOR DYEING KERATIN FIBRES, COMPRISING AN ELECTROPHILIC MONOMER, A HYDROPHOBIC DIRECT DYE AND A LIQUID ORGANIC SOLVENT | L'ORÉAL (FR) | 2007-10-25 | — | — | WO | disclosed |
| US-20060110334-A1 | Two-compartment aerosol device comprising electrophilic monomers, and use thereof for the cosmetic treatment of the hair | L'OREAL S.A. (FR) | 2006-05-25 | — | — | US | disclosed |
| US-20060088493-A1 | Composition and process for the cosmetic treatment of keratin materials based on electrophilic monomers and non-silicone polymers | L'OREAL S.A. (FR) | 2006-04-27 | — | — | US | disclosed |
| US-20060088488-A1 | Dyeing composition comprising a mixture of at least one pigment and at least one electrophilic monomer | L'OREAL S.A. (FR) | 2006-04-27 | — | — | US | disclosed |
| US-20060085922-A1 | Oxidizing composition comprising at least one electrophilic monomer and at least one non-benzoquinone oxidant | L'OREAL S.A. (FR) | 2006-04-27 | — | — | US | disclosed |
| CN-1762327-A | Use for the cosmetic treatment of keratinous material of not sticky compositions based on electrophilic monomers and non-silicon polymers | OREAL (FR) | 2006-04-26 | — | — | CN | disclosed |
| US-20060083706-A1 | Haircare composition comprising at least one electrophilic monomer and micro- or nanoparticles of at least one solid lubricant | L'OREAL S.A. (FR) | 2006-04-20 | — | — | US | disclosed |
| US-20060083762-A1 | Uses of compositions comprising electrophilic monomers and micro-particles or nanoparticles | L'OREAL S.A. (FR) | 2006-04-20 | — | — | US | disclosed |
| US-20060080792-A1 | Film-forming composition for the cosmetic treatment of keratin materials comprising at least one electrophilic monomer and at least one non-silicone polymer | L'OREAL S.A. (FR) | 2006-04-20 | — | — | US | disclosed |
| US-20060078523-A1 | Composition comprising at least one electrophilic monomer and at least one acid in a cosmetically acceptable anhydrous medium, and use thereof for cosmetic treatment of the hair | L'OREAL S.A. (FR) | 2006-04-13 | — | — | US | disclosed |
| US-20060078522-A1 | Composition for treating keratin materials comprising at least one electrophilic monomer and at least one salt | L'OREAL S.A. (FR) | 2006-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (14 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080038218-A1 | Cosmetic composition comprising at least one electrophilic monomer, at least one fluoro compound and at least one liquid organic solvent | KRT18, CUTA, FLNA | USP2 3896/4885TSHR 3393/4885CA1 3300/4885 |
| US-20060110334-A1 | Two-compartment aerosol device comprising electrophilic monomers, and use thereof for the cosmetic treatment of the hair | POLR1C, TRPA1, GSTM2 | USP2 786/4885TSHR 4318/4885CA1 3614/4885 |
| US-20070251028-A1 | Dyeing composition comprising at least one electrophilic monomer, one hydrophilic dye and one liquid organic solvent | KRT18, DSG1, IK | USP2 1684/4885TSHR 4753/4885CA1 2562/4885 |
| US-20060088493-A1 | Composition and process for the cosmetic treatment of keratin materials based on electrophilic monomers and non-silicone polymers | KRT18, CUTA, MARK1 | USP2 2854/4885TSHR 4581/4885CA1 3524/4885 |
| US-20060083762-A1 | Uses of compositions comprising electrophilic monomers and micro-particles or nanoparticles | KRT18, PRKDC, ACP1 | USP2 1971/4885TSHR 4297/4885CA1 2181/4885 |
| US-20100172858-A1 | COSMETIC COMPOSITION COMPRISING AT LEAST ONE POLYMER OBTAINED FROM A DIELECTROPHILIC MONOMER | KRT18, DSG1, DSC1 | USP2 4029/4885TSHR 4403/4885CA1 1180/4885 |
| US-20060085922-A1 | Oxidizing composition comprising at least one electrophilic monomer and at least one non-benzoquinone oxidant | KRT18, GPX4, NOX4 | USP2 1996/4885TSHR 4243/4885CA1 3266/4885 |
| US-20060083706-A1 | Haircare composition comprising at least one electrophilic monomer and micro- or nanoparticles of at least one solid lubricant | MITF, CUTA, NACA | USP2 1866/4885TSHR 3327/4885CA1 3873/4885 |
| US-20060078523-A1 | Composition comprising at least one electrophilic monomer and at least one acid in a cosmetically acceptable anhydrous medium, and use thereof for cosmetic treatment of the hair | HOGA1, OAT, SUCLG1 | USP2 3505/4885TSHR 4459/4885CA1 841/4885 |
| US-20060088488-A1 | Dyeing composition comprising a mixture of at least one pigment and at least one electrophilic monomer | KRT18, IK, DDR1 | USP2 4315/4885TSHR 4653/4885CA1 2129/4885 |
| US-20060078522-A1 | Composition for treating keratin materials comprising at least one electrophilic monomer and at least one salt | KRT18, DSG1, DSC1 | USP2 4051/4885TSHR 4360/4885CA1 787/4885 |
| US-20070251027-A1 | Dyeing composition comprising at least one soluble fluorescent compound, at least one electrophilic monomer and at least one liquid organic solvent | KRT18, VIM, DSG1 | USP2 3188/4885TSHR 4879/4885CA1 3349/4885 |
| US-20070253927-A1 | Cosmetic compositions comprising at least one dielectrophile monomer and at least one radical initiator | KRT18, DSG1, PRKDC | USP2 2028/4885TSHR 4464/4885CA1 2941/4885 |
| US-20120156270-A1 | METHOD FOR SMOOTHING OUT THE SKIN BY FILLING IN RECESSED PORTIONS | EPAS1, PGF, PASK | USP2 2168/4885TSHR 4804/4885CA1 4402/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.