SCHEMBL331218

SCHEMBL331218

S=C=Nc1ccc(N=C=S)s1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MIF P14174 1/20 0.42
P2RY6 Q15077 1/20 0.37
ALDH1A1 P00352 2/20 0.33
GABRA1 P14867 1/20 0.33
GABRB2 P47870 1/20 0.33
ABCB11 O95342 1/20 0.33
NR3C1 P04150 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
ADRA2A P08913 1/20 0.33
ADORA3 P0DMS8 1/20 0.33
HPGD P15428 1/20 0.33
ALOX15 P16050 1/20 0.33
ADRA2C P18825 1/20 0.33
MAOA P21397 1/20 0.33
DRD1 P21728 1/20 0.33
SLC6A4 P31645 1/20 0.33
HTR2B P41595 1/20 0.33
CCR2 P41597 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5824801 0.83
SCHEMBL14846457 0.83
SCHEMBL5825383 0.83
SCHEMBL7866707 0.79 MIF (0.32) MIF
SCHEMBL5570720 0.69
SCHEMBL6310453 0.67
SCHEMBL29610590 0.67 CYP2A6 (0.40) MIFALDH1A1ABCB11NR3C1CYP1A2
SCHEMBL9811930 0.67 CYP2A6 (0.40) MIFALDH1A1ABCB11NR3C1CYP1A2
Bitoscanate SCHEMBL157128 0.65 MIF (0.72) MIFP2RY6ALDH1A1GABRA1GABRB2
SCHEMBL28571583 0.64 MIF (0.37) MIFALDH1A1GABRA1GABRB2ABCB11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 552 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122094934-A Polythiol composition and use thereof 2026-05-26 CN disclosed
US-12630694-B2 Polythiol composition, polymerizable composition, resin, molded body, optical material, and lens MITSUI CHEMICALS, INC. (JP) 2026-05-19 US disclosed
EP-3861977-B1 (METH)ACRYLATE, MONOMER COMPOSITION, MOLDED BODY, COMPOSITION FOR DENTAL MATERIAL, AND DENTAL MATERIAL MITSUI CHEMICALS INC (JP) 2026-05-06 EP disclosed
EP-4733341-A1 POLYMERIZABLE COMPOSITION AND METHOD FOR PRODUCING SAME, RESIN, MOLDED BODY, OPTICAL MATERIAL, AND LENS Mitsui Chemicals, Inc. (JP) 2026-04-29 EP disclosed
US-12605306-B2 Method of manufacturing monomer composition, raw material composition, monomer composition, curable composition, and molded body MITSUI CHEMICALS, INC. (JP) 2026-04-21 US disclosed
US-12606675-B2 Sulfur-containing polymer, method for producing same, and sulfur-containing polymer composition NIPPON SHOKUBAI CO., LTD. (JP) 2026-04-21 US disclosed
US-12583964-B2 Polythiol composition, polymerizable composition, resin, molded article, optical material, and lens MITSUI CHEMICALS, INC. (JP) 2026-03-24 US disclosed
EP-4198617-B1 POLYTHIOL COMPOSITION, POLYMERIZABLE COMPOSITION, RESIN, MOLDED ARTICLE, OPTICAL MATERIAL, AND LENS MITSUI CHEMICALS INC (JP) 2026-01-28 EP disclosed
US-12441821-B2 (Meth)acrylate and use thereof MITSUI CHEMICALS, INC. (JP) 2025-10-14 US disclosed
EP-4603479-A1 POLYTHIOL COMPOSITION, POLYMERIZABLE COMPOSITION, RESIN, MOLDED BODY, OPTICAL MATERIAL AND LENS Mitsui Chemicals, Inc. (JP) 2025-08-20 EP disclosed
EP-0665219-B1 Polythiol, process for producing same, sulfur-containing urethane-base resin prepared from the polythiol, process for producing the resin, and lens MITSUI TOATSU CHEMICALS (JP) 1998-04-22 EP disclosed
US-5736609-A A POLYTHIO COMPOUND CONTAINING AT LEAST TWO MERCAPTO GROUPS, A POLYISO(THIO)CYANATE COMPOUND, AND A COMPOUND HAVING TWO OR MORE UNSATURATED REACTIVE GROUPS MITSUI TOATSU CHEMICALS, INC. (JP) 1998-04-07 US disclosed
EP-0553801-B1 Use of sulfur-containing acid phosphoric ester as internal release agent MITSUI TOATSU CHEMICALS (JP) 1997-04-23 EP disclosed
US-5608115-A Polythiol useful for preparing sulfur-containing urethane-based resin and process for producing the same MITSUI TOATSU CHEMICALS, INC. (JP) 1997-03-04 US disclosed
EP-0751161-A2 Sulfur-containing urethane-based resin composition, optical element and lens comprising this resin MITSUI TOATSU CHEMICALS, Inc. (JP) 1997-01-02 EP disclosed
EP-0665219-A1 Polythiol, process for producing same, sulfur-containing urethane-base resin prepared from the polythiol, process for producing the resin, and lens MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1995-08-02 EP disclosed
US-5389708-A Polymerizing polyisocyanate or polyisothiocyanate with polyol or polythiol in presence of thiophosphoric or dithiophosphoric acid ester MITSUI TOATSU CHEMICALS, INC. (JP) 1995-02-14 US disclosed
EP-0351073-B1 Lens comprising a resin having a large refractive index and process for preparing the lens MITSUI TOATSU CHEMICALS (JP) 1994-09-21 EP disclosed
EP-0553801-A1 Use of sulfur-containing acid phosphoric ester as internal release agent MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-08-04 EP disclosed
US-5084545-A Polythiourethanes for impact strength, lightweight lenses MITSUI TOATSU CHEMICALS, INC. (JP) 1992-01-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12630694-B2 Polythiol composition, polymerizable composition, resin, molded body, optical material, and lens TXNL1, ALG3, TCOF1 MIF 2852/4885P2RY6 3649/4885ALDH1A1 2820/4885
US-12606675-B2 Sulfur-containing polymer, method for producing same, and sulfur-containing polymer composition UACA, SMC3, SMC2 MIF 2570/4885P2RY6 2542/4885ALDH1A1 1086/4885
US-12605306-B2 Method of manufacturing monomer composition, raw material composition, monomer composition, curable composition, and molded body ADH1A, ADH1C, ADH5 MIF 1119/4885P2RY6 4683/4885ALDH1A1 15/4885
US-12441821-B2 (Meth)acrylate and use thereof TST, MMAB, BHMT2 MIF 142/4885P2RY6 2353/4885ALDH1A1 144/4885
US-12583964-B2 Polythiol composition, polymerizable composition, resin, molded article, optical material, and lens EPN1, SEM1, PFN1 MIF 2580/4885P2RY6 2578/4885ALDH1A1 2000/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.