Sugi Predict

Sugi Predict / Compounds / SCHEMBL336773

SCHEMBL336773

SCHEMBL336773

Cc1ccc([C](c2ccccc2)c2ccc(C)cc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CES2 O00748 2/20 0.65
▸ CES1 P23141 2/20 0.65
▸ NPC1 O15118 4/20 0.58
▸ RAB9A P51151 4/20 0.58
▸ MEN1 O00255 1/20 0.58
▸ KMT2A Q03164 1/20 0.58
▸ LMNA P02545 3/20 0.53
▸ ACHE P22303 2/20 0.53
▸ TSHR P16473 1/20 0.53
▸ ALOX12 P18054 1/20 0.53
▸ ALDH1A1 P00352 3/20 0.52
▸ SMN1; SMN2 Q16637 2/20 0.52
▸ POLB P06746 1/20 0.52
▸ HPGD P15428 2/20 0.48
▸ MAPT P10636 2/20 0.48
▸ CYP2D6 P10635 1/20 0.48
▸ HIF1A Q16665 1/20 0.48
▸ AKR1C3 P42330 1/20 0.48
▸ SRD5A2 P31213 1/20 0.46
▸ CTSL P07711 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL60996 1.00 CES2 (0.65) CES2CES1NPC1RAB9AMEN1
SCHEMBL1775710 0.88 ALDH1A1 (0.58) CES2CES1NPC1RAB9AMEN1
SCHEMBL69744 0.83 CES2 (0.65) CES2CES1NPC1RAB9AMEN1
SCHEMBL15301748 0.83 CES2 (0.65) CES2CES1NPC1RAB9AMEN1
SCHEMBL69743 0.83 CES2 (0.65) CES2CES1NPC1RAB9AMEN1
SCHEMBL143 0.82 CES1 (0.53) CES2CES1MEN1KMT2ALMNA
SCHEMBL259065 0.79 ALDH1A1 (0.80) CES2CES1NPC1RAB9AMEN1
Benzophenone SCHEMBL5162782 0.79 ALDH1A1 (0.80) CES2CES1NPC1RAB9AMEN1
SCHEMBL4738437 0.79 CES2 (0.60) CES2CES1NPC1RAB9AMEN1
SCHEMBL22101687 0.79 CES2 (0.60) CES2CES1NPC1RAB9AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 480 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118084988-A Polymerization monomer for preparing beta-1, 3 glucan and polymerization method 山东大学 2024-05-28 — — CN claimed
US-11827667-B2 Production method for guanosine derivative having fluorine atom-containing functional group at position 8 and application thereof UNIVERSITY OF MIYAZAKI (JP) 2023-11-28 — — US claimed
CN-111925403-A Glucosamine donors and application thereof 山东大学 2020-11-13 — — CN claimed
EP-2623507-B1 MORPHOLINO NUCLEIC ACID DERIVATIVE NIPPON SHINYAKU CO LTD (JP) 2016-11-02 — — EP claimed
US-8592214-B2 Chemical reaction monitor ILLUMINA, INC. (US) 2013-11-26 — — US claimed
US-20130197220-A1 Morpholino Nucleic Acid Derivatives NIPPON SHINYAKU CO., LTD. (JP) 2013-08-01 — — US claimed
US-20130052690-A1 PCR PRIMER AND METHOD FOR REDUCING NON-SPECIFIC NUCLEIC ACID AMPLIFICATION USING A PHOTOLABILE PROTECTING GROUP SAMSUNG ELECTRONICS CO., LTD. (KR) 2013-02-28 — — US claimed
US-8299206-B2 Method of synthesis of morpholino oligomers AVI BIOPHARMA, INC. (US) 2012-10-30 — — US claimed
US-8076476-B2 Synthesis of morpholino oligomers using doubly protected guanine morpholino subunits AVI BIOPHARMA, INC. (US) 2011-12-13 — — US claimed
US-20110136684-A1 CHEMICAL REACTION MONITOR ILLUMINA, INC. 2011-06-09 — — US claimed
WO-2006031814-A2 ELECTROCHEMICAL DEBLOCKING USING A HYDRAZINE DERIVATIVE COMBIMATRIX CORPORATION (US) 2006-03-23 — — WO claimed
US-20060054511-A1 Electrochemical deblocking using a hydrazine derivative CUSTOMARRAY, INC. 2006-03-16 — — US claimed
WO-2006019471-A2 FLUID PROCESSING DEVICE APPLERA CORPORATION (US) 2006-02-23 — — WO claimed
US-20060013742-A1 Fluid processing device APPLIED BIOSYSTEMS, LLC 2006-01-19 — — US claimed
EP-1236736-A1 2-AMINOPURINE DERIVATIVES HISAMITSU PHARMACEUTICAL CO. INC. (JP) 2002-09-04 — — EP claimed
US-6165726-A Non-radioactive methods for chemical cleavage sequencing and footprinting of nucleic acids UT-BATTELLE, LLC (US) 2000-12-26 — — US claimed
EP-0536710-B1 Amino acid derivatives for peptide synthesis BACHEM FEINCHEMIKALIEN AG (CH) 1996-05-08 — — EP claimed
US-5455363-A Having trityl as amide-protecting group for asparagine and glutamine; reduced side reaction GOSTELI JACQUES (CH) 1995-10-03 — — US claimed
US-5221736-A Sequential peptide and oligonucleotide syntheses using immunoaffinity techniques BIONEBRASKA, INC. (US) 1993-06-22 — — US claimed
EP-0536710-A1 Amino acid derivatives for peptide synthesis BACHEM FEINCHEMIKALIEN AG (CH) 1993-04-14 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130052690-A1 PCR PRIMER AND METHOD FOR REDUCING NON-SPECIFIC NUCLEIC ACID AMPLIFICATION USING A PHOTOLABILE PROTECTING GROUP POLL, POLRMT, POLN CES2 1593/4885CES1 1267/4885NPC1 3926/4885
US-20130197220-A1 Morpholino Nucleic Acid Derivatives MORF4L1, METTL16, METTL3 CES2 4444/4885CES1 3415/4885NPC1 3060/4885
US-11827667-B2 Production method for guanosine derivative having fluorine atom-containing functional group at position 8 and application thereof RNMT, FBL, NOP2 CES2 4421/4885CES1 4408/4885NPC1 2063/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.