Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG known ✓ | P37231 | 1/20 | 0.32 |
| ▸ | RAD51 | Q06609 | 3/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 6/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | PKLR | P30613 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28674571 | 0.90 | RAD51 (0.38) | RAD51NFE2L2TRPA1TRPV1PKLR | |
| SCHEMBL3936742 | 0.86 | NFE2L2 (0.41) | RAD51NFE2L2TRPA1NR1H2LMNA | |
| SCHEMBL14484833 | 0.84 | NFE2L2 (0.42) | RAD51NFE2L2TRPA1NR1H2LMNA | |
| SCHEMBL14484832 | 0.84 | NFE2L2 (0.42) | RAD51NFE2L2TRPA1NR1H2LMNA | |
| SCHEMBL2524357 | 0.84 | NFE2L2 (0.42) | RAD51NFE2L2TRPA1NR1H2PTPN1 | |
| (Z)-1,2-Diphenylethene SCHEMBL28675607 | 0.83 | PTPN1 (0.39) | RAD51NFE2L2TRPV1PKLRPTPN1 | |
| SCHEMBL2528157 | 0.81 | TRPA1 (0.40) | NFE2L2TRPA1TRPV1NR1H2LMNA | |
| SCHEMBL566321 | 0.80 | TRPA1 (0.39) | NFE2L2TRPA1TRPV1NR1H2SLC16A3 | |
| SCHEMBL27453977 | 0.79 | RAD51 (0.48) | RAD51NFE2L2TRPA1NR1H2LMNA | |
| SCHEMBL15982 | 0.78 | TRPV1 (0.32) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230371513-A1 | PHOTOSTABLE COMPOSITION AND METHOD OF REDUCING OR CONTROLLING WEED POPULATION APPLYING SAID COMPOSITION | UPL DO BRASIL INDUSTRIA E COMERCIO DE INSUMOS AGROPECUARIOS S.A. (BR) | 2023-11-23 | — | — | US | disclosed |
| CN-108368154-B | Polypeptides | 诺维信公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-108350441-B | Polypeptides | 诺维信公司 | 2022-09-27 | — | — | CN | disclosed |
| CN-109072133-B | Use of polypeptides having dnase activity for treating textiles | 诺维信公司 | 2021-06-15 | — | — | CN | disclosed |
| CN-112969775-A | Cleaning composition | 诺维信公司 | 2021-06-15 | — | — | CN | disclosed |
| CN-112899086-A | Detergent composition | 诺维信公司 | 2021-06-04 | — | — | CN | disclosed |
| CN-108350400-B | Laundry washing method, use of polypeptides and detergent compositions | 诺维信公司 | 2021-03-30 | — | — | CN | disclosed |
| CN-112423728-A | Detergent composition | 龙沙有限责任公司 | 2021-02-26 | — | — | CN | disclosed |
| CN-106164236-B | Detergent composition | 诺维信公司 | 2021-02-02 | — | — | CN | disclosed |
| CN-112262207-A | Polypeptides comprising carbohydrate-binding activity in detergent compositions and their use for reducing wrinkles in textiles or fabrics | 诺维信公司 | 2021-01-22 | — | — | CN | disclosed |
| CN-106795463-B | Polypeptides having DNase activity for reducing static electricity | 诺维信公司 | 2020-09-29 | — | — | CN | disclosed |
| CN-106414698-B | Detergent composition | 诺维信公司 | 2020-02-21 | — | — | CN | disclosed |
| WO-2020036064-A1 | OIL-IN-WATER EMULSION COSMETIC COMPOSITION | ダウ・東レ株式会社 | 2020-02-20 | — | — | WO | disclosed |
| US-9125411-B2 | UV absorbers for reducing the E/Z isomerization of pesticides | BASF SE (DE) | 2015-09-08 | — | — | US | disclosed |
| WO-2013072852-A4 | STRETCH MARK PREVENTER | JINDAL SONIA H (IN) | 2013-07-11 | — | — | WO | disclosed |
| WO-2013072852-A1 | STRETCH MARK PREVENTER | JINDAL SONIA H (IN) | 2013-05-23 | — | — | WO | disclosed |
| EP-2584896-A2 | HERBICIDAL COMPOSITIONS | BASF SE (DE) | 2013-05-01 | — | — | EP | disclosed |
| US-20130102463-A1 | Herbicidal Compositions | BASF SE (DE) | 2013-04-25 | — | — | US | disclosed |
| WO-2011161105-A2 | HERBICIDAL COMPOSITIONS | BASF SE (DE) | 2011-12-29 | — | — | WO | disclosed |
| US-20110257265-A1 | UV Absorbers for Reducing the E/Z Isomerization of Pesticides | BASF SE (DE) | 2011-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130102463-A1 | Herbicidal Compositions | PPOX, PAOX, DDT | PPARG 641/4885RAD51 3292/4885NFE2L2 1851/4885 |
| US-20110257265-A1 | UV Absorbers for Reducing the E/Z Isomerization of Pesticides | DDT, PIN1, ERCC4 | PPARG 1080/4885RAD51 1225/4885NFE2L2 704/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.