SCHEMBL39033

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL39571	0.89	KAT8 (0.50)	PTPN1PTPN11KAT8PPARACYP3A4
	Grevillol SCHEMBL31345744	0.86	KAT8 (0.59)	PTPN1PTPN11KAT8MCL1PPARA
	SCHEMBL39025	0.85	CA12 (0.45)	PTPN1PTPN11KAT8PPARAPTPN2
	SCHEMBL19433113	0.81	CA12 (0.50)	PTPN1PTPN11PTPN2CA12CA1
	SCHEMBL15537699	0.81	PTPN1 (0.42)	PTPN1PTPN11PTPN2PGAM1CA12
	SCHEMBL6832976	0.80	HTT (0.52)	PTPN1PTPN11PGAM1ALOX5PTGS2
	SCHEMBL22660353	0.79	CA12 (0.40)	PTPN1PTPN11KAT8PPARACA12
	SCHEMBL22629	0.78	LDHA (0.49)	PTPN1PTPN11KAT8MCL1PPARA
	SCHEMBL27639352	0.78	LDHA (0.49)	PTPN1PTPN11KAT8MCL1PPARA
	SCHEMBL3392969	0.77	CA2 (0.45)	PTPN1PTPN11CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.