Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLTC | Q00610 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL301992 | 0.82 | MEN1 (0.30) | MEN1PKMKMT2ASMN1; SMN2 | |
| Potassium Ion SCHEMBL9152245 | 0.81 | — | — | |
| Potassium Ion SCHEMBL9152893 | 0.72 | — | — | |
| Potassium Ion SCHEMBL31670338 | 0.62 | CLTC (0.46) | CLTCMEN1KMT2A | |
| Potassium Ion SCHEMBL4636440 | 0.62 | CLTC (0.46) | CLTCMEN1KMT2A | |
| SCHEMBL170998 | 0.60 | ALDH1A1 (0.39) | MEN1PKMKMT2ASMN1; SMN2 | |
| SCHEMBL19357602 | 0.59 | PRKD3 (0.34) | MEN1PKMKMT2ASMN1; SMN2 | |
| SCHEMBL9293198 | 0.58 | CASP6 (0.47) | MEN1KMT2ASMN1; SMN2 | |
| Potassium Ion SCHEMBL3817947 | 0.58 | DUSP5 (0.47) | MEN1PKMKMT2A | |
| Potassium Ion SCHEMBL9082284 | 0.57 | CASP1 (0.54) | CLTCMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7550447-B2 | Method for precipitating nucleic acid with visible carrier | MERCK PATENT GMBH (DE) | 2009-06-23 | — | — | US | claimed |
| US-20070178601-A1 | METHOD FOR PRECIPITATING NUCLEIC ACID WITH VISIBLE CARRIER | EMD BIOSCIENCES, INC. | 2007-08-02 | — | — | US | claimed |
| US-7144713-B1 | Method for precipitating nucleic acid with visible carrier | EMD BIOSCIENCES, INC. (US) | 2006-12-05 | — | — | US | claimed |
| EP-0853680-B1 | METHOD FOR PRECIPITATING NUCLEIC ACID WITH VISIBLE CARRIER | EMD BIOSCIENCES INC (US) | 2004-03-31 | — | — | EP | claimed |
| US-10030275-B2 | Primer and probe sequences for detecting chlamydia trachomatis | ABBOTT MOLECULAR INC. (US) | 2018-07-24 | — | — | US | disclosed |
| EP-2514838-B1 | Primer and probe sequences for detecting chlamydia trachomatis | ABBOTT MOLECULAR INC (US) | 2017-12-06 | — | — | EP | disclosed |
| US-20160002711-A1 | PRIMER AND PROBE SEQUENCES FOR DETECTING CHLAMYDIA TRACHOMATIS | ABBOTT MOLECULAR INC. | 2016-01-07 | — | — | US | disclosed |
| US-9102986-B2 | Primer and probe sequences for detecting Chlamydia trachomatis | ABBOTT MOLECULAR INC. (US) | 2015-08-11 | — | — | US | disclosed |
| EP-2514838-A1 | Primer and probe sequences for detecting chlamydia trachomatis | Abbott Laboratories (US) | 2012-10-24 | — | — | EP | disclosed |
| EP-2035440-B1 | PRIMER AND PROBE SEQUENCES FOR DETECTING CHLAMYDIA TRACHOMATIS | ABBOTT LAB (US) | 2012-06-13 | — | — | EP | disclosed |
| US-20080299567-A1 | PRIMER AND PROBE SEQUENCES FOR DETECTING CHLAMYDIA TRACHOMATIS | ABBOTT LABORATORIES (US) | 2008-12-04 | — | — | US | disclosed |