Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17689094 | 0.84 | ACHE (0.46) | KEAP1NFE2L2MEN1HPGDKMT2A | |
| SCHEMBL13131553 | 0.84 | SLC40A1 (0.44) | KEAP1NFE2L2MEN1HPGDKMT2A | |
| SCHEMBL23507187 | 0.84 | TRPA1 (0.48) | KEAP1NFE2L2MEN1HPGDKMT2A | |
| SCHEMBL5638259 | 0.84 | CD44 (0.48) | KEAP1NFE2L2MEN1HPGDKMT2A | |
| SCHEMBL30450974 | 0.82 | ALDH1A1 (0.56) | KEAP1NFE2L2MEN1HPGDKMT2A | |
| SCHEMBL1200695 | 0.82 | ALDH1A1 (0.56) | KEAP1NFE2L2MEN1HPGDKMT2A | |
| SCHEMBL31311046 | 0.80 | CA2 (0.42) | MAPK1ALDH1A1CA1CA2CA7 | |
| SCHEMBL2052455 | 0.80 | KMT2A (0.45) | KEAP1NFE2L2MEN1KMT2ACYP1A2 | |
| SCHEMBL647766 | 0.79 | KEAP1 (0.35) | KEAP1NFE2L2MEN1HPGDKMT2A | |
| SCHEMBL15461578 | 0.79 | TSHR (0.52) | KEAP1NFE2L2MEN1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111170908-B | Synthesis method of 2, 4-dimethyl-3-methylsulfonyl halogeno-benzene | 北京印刷学院 | 2021-08-17 | — | — | CN | claimed |
| CN-111170908-A | Synthesis method of 2, 4-dimethyl-3-methylsulfonyl halogeno-benzene | 北京印刷学院 | 2020-05-19 | — | — | CN | claimed |
| EP-1718605-B1 | PROCESSES FOR THE PREPARATION OF ARYL-AND HETEROARYL-ALKYLSULFONYL HALIDES | WYETH CORP (US) | 2009-06-17 | — | — | EP | claimed |
| CN-111170908-B | Synthesis method of 2, 4-dimethyl-3-methylsulfonyl halogeno-benzene | 北京印刷学院 | 2021-08-17 | — | — | CN | disclosed |
| CN-111170908-B | Synthesis method of 2, 4-dimethyl-3-methylsulfonyl halogeno-benzene | 北京印刷学院 | 2021-08-17 | — | — | CN | disclosed |
| CN-111170908-A | Synthesis method of 2, 4-dimethyl-3-methylsulfonyl halogeno-benzene | 北京印刷学院 | 2020-05-19 | — | — | CN | disclosed |
| CN-111170908-A | Synthesis method of 2, 4-dimethyl-3-methylsulfonyl halogeno-benzene | 北京印刷学院 | 2020-05-19 | — | — | CN | disclosed |
| US-20140038822-A1 | USE OF SUBSTITUTED SPIROCYCLIC SULFONAMIDOCARBOXYLIC ACIDS, CARBOXYLIC ESTERS THEREOF, CARBOXAMIDES THEREOF AND CARBONITRILES THEREOF OR SALTS THEREOF FOR ENHANCEMENT OF STRESS TOLERANCE IN PLANTS | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-02-06 | — | — | US | disclosed |
| US-20090306376-A1 | OPTICAL RECORDING MEDIUM AND COMPOUND USED FOR THE SAME | MITSUI CHEMICALS, INC. (JP) | 2009-12-10 | — | — | US | disclosed |
| US-20090163692-A1 | AROMATIC POLYETHERS | GENERAL ELECTRIC COMPANY (US) | 2009-06-25 | — | — | US | disclosed |
| US-20080318966-A1 | Sinomenine Derivatives and Preparation and Uses Thereof | NIMBUS INNOWORKS LIMITED (CN) | 2008-12-25 | — | — | US | disclosed |
| US-7405030-B2 | Imide compound and optical recording media made by using the same | MITSUI CHEMICALS, INC. (JP) | 2008-07-29 | — | — | US | disclosed |
| EP-1930339-A2 | Imide compound | MITSUI CHEMICALS, INC. (JP) | 2008-06-11 | — | — | EP | disclosed |
| US-20070259151-A1 | Imide compound and optical recording media made by using the same | MITSUI CHEMICALS, INC. (JP) | 2007-11-08 | — | — | US | disclosed |
| US-7259260-B2 | Imide compound and optical recording media made by using the same | MITSUI CHEMICALS, INC. (JP) | 2007-08-21 | — | — | US | disclosed |
| WO-2007070703-A2 | SINOMENINE DERIVATIVES AND PREPARATION AND USES THEREOF | NATUREMED GROUP CORPORATION (US) | 2007-06-21 | — | — | WO | disclosed |
| US-20070054084-A1 | Optical recording medium and compound used for the same | MITSUI CHEMICALS, INC. (JP) | 2007-03-08 | — | — | US | disclosed |
| EP-1672626-A1 | OPTICAL RECORDING MEDIUM AND COMPOUND USED IN THE OPTICAL RECORDING MEDIUM | Mitsui Chemicals, Inc. (JP) | 2006-06-21 | — | — | EP | disclosed |
| US-20050208425-A1 | Imide compound and optical recording media made by using the same | YAMAMOTO CHEMICALS, INC. (JP) | 2005-09-22 | — | — | US | disclosed |
| EP-1445115-A1 | IMIDE COMPOUNDS AND OPTICAL RECORDING MEDIA MADE BY USING THE SAME | Mitsui Chemicals, Inc. (JP) | 2004-08-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090306376-A1 | OPTICAL RECORDING MEDIUM AND COMPOUND USED FOR THE SAME | CACNA1B, KCNN4, KCNN2 | KEAP1 3863/4885NFE2L2 2216/4885MEN1 979/4885 |
| US-20080318966-A1 | Sinomenine Derivatives and Preparation and Uses Thereof | OPRM1, SIN3A, MIF | KEAP1 537/4885NFE2L2 452/4885MEN1 2924/4885 |
| US-20050208425-A1 | Imide compound and optical recording media made by using the same | CRY1, MTNR1A, TRPA1 | KEAP1 3821/4885NFE2L2 523/4885MEN1 18/4885 |
| US-20140038822-A1 | USE OF SUBSTITUTED SPIROCYCLIC SULFONAMIDOCARBOXYLIC ACIDS, CARBOXYLIC ESTERS THEREOF, CARBOXAMIDES THEREOF AND CARBONITRILES THEREOF OR SALTS THEREOF FOR ENHANCEMENT OF STRESS TOLERANCE IN PLANTS | STS, SCLY, TST | KEAP1 326/4885NFE2L2 793/4885MEN1 4322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.