SCHEMBL4351696

SCHEMBL4351696

CC(=Nc1c(C)cccc1C)C(C)=Nc1c(C)cccc1C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 4/20 0.50
GRIN2D O15399 2/20 0.50
GRIN3B O60391 2/20 0.50
GRIN1 Q05586 2/20 0.50
GRIN2A Q12879 2/20 0.50
GRIN2B Q13224 2/20 0.50
GRIN2C Q14957 2/20 0.50
GRIN3A Q8TCU5 2/20 0.50
ATM Q13315 3/20 0.46
KMT2A Q03164 2/20 0.46
MEN1 O00255 1/20 0.46
HSP90AA1 P07900 1/20 0.46
ALDH1A1 P00352 3/20 0.43
CYP2A6 P11509 2/20 0.39
CYP1A2 P05177 1/20 0.39
TRPA1 O75762 2/20 0.39
TSHR P16473 1/20 0.38
ACHE P22303 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5354754 1.00 SIGMAR1 (0.50) SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL4351689 1.00 SIGMAR1 (0.50) SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL5588010 0.97 SIGMAR1 (0.48) SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A
Hydrochloric Acid SCHEMBL11298158 0.95 SIGMAR1 (0.47) SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A
Hydrochloric Acid SCHEMBL11298156 0.95 SIGMAR1 (0.47) SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL3736651 0.93 SIGMAR1 (0.46) SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL7056457 0.93 SIGMAR1 (0.46) SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL6056657 0.91 SIGMAR1 (0.44) SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL6056681 0.91 SIGMAR1 (0.44) SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL11298160 0.91 SIGMAR1 (0.44) SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1110941-B1 Process for the codimerisation of polyunsaturated fatty compounds and olefines with iron complexes INST FRANCAIS DU PETROLE (FR) 2004-03-17 EP claimed
US-12544733-B2 Gas/liquid oligomerization reactor having successive zones with variable diameters IFP Energies Nouvelles (FR) 2026-02-10 US disclosed
US-12479780-B2 Oligomerisation process comprising a step of recycling a pre-cooled solvent IFP Energies Nouvelles (FR) 2025-11-25 US disclosed
US-12364960-B2 Method for oligomerization in a reactor comprising a gas/liquid double distributor IFP Energies Nouvelles (FR) 2025-07-22 US disclosed
US-12312288-B2 Gas/liquid oligomerization reactor comprising transverse internals IFP Energies Nouvelles (FR) 2025-05-27 US disclosed
US-20250084014-A1 OLIGOMERISATION PROCESS COMPRISING A STEP OF RECYCLING A PRE-COOLED SOLVENT IFP Energies Nouvelles (FR) 2025-03-13 US disclosed
CN-119409591-A Preparation method of alpha-diimine ligand, nickel catalyst thereof and application of nickel catalyst in olefin polymerization 中国科学院长春应用化学研究所 2025-02-11 CN disclosed
US-12168213-B2 Ethylene oligomerization plant for producing alpha-olefins IFP Energies Nouvelles (FR) 2024-12-17 US disclosed
US-12157712-B2 Oligomerization process implementing the recycling of the gas headspace IFP Energies Nouvelles (FR) 2024-12-03 US disclosed
US-12151994-B2 Method for oligomerising olefins in an olifomerisation reactor IFP Energies Nouvelles (FR) 2024-11-26 US disclosed
US-20030225303-A1 Hydroformylation process employing a cobalt-based catalyst in a non-aqueous liquid with improved catalyst recycling INSTITUT FRANCAIS DU PETROLE (FR) 2003-12-04 US disclosed
US-6617474-B2 Reacting olefinically unsaturated compound with carbon monoxide and hydrogen in presence of polar phase comprising: a non-aqueous ionic liquid comprising quaternary ammonium and/or a quaternary phosphonium compound and catalyst; adding solvent INSTITUT FRANCAIS DU PETROLE (FR) 2003-09-09 US disclosed
US-20030055299-A1 Catalyst based on cobalt and/or rhodium employed in a two-phase medium INSTITUT FRANCAIS DU PETROLE (FR) 2003-03-20 US disclosed
US-6469216-B2 CO OR RH COMPLEX COORDINATED WITH A NITROGEN-CONTAINING LIGAND; QUATERNARY AMMONIUM OR PHOSPHONIUM IONIC SOLVENT INSTITUT FRANCAIS DU PETROLE (FR) 2002-10-22 US disclosed
US-6444831-B2 A MONOOLEFINIC COMPOUND IS ADDED TO A FATTY SUBSTANCE THAT COMPRISES TWO CONJUGATED OR UNCONJUGATED ETHYELNE BONDS IN PRESENCE OF A CATALYTIC SYSTEM CONTAINING IRON COMPOUNDS, A REDUCING AGENT, A LIGAND WHICH CONTAINS NITROGEN, ARSANIC ETC INSTITUT FRANCAIS DU PETROLE (FR) 2002-09-03 US disclosed
US-20020099243-A1 Process for the hydroformylation of olefinically unsaturated compounds in a non-aqueous ionic solvent INSTITUT FRANCAIS DU PETROLE (FR) 2002-07-25 US disclosed
US-20010039363-A1 Process for hydroformylation using a catalyst based on cobalt and/or rhodium employed in a two-phase medium INSTITUT FRANCAIS DU PETROLE (FR) 2001-11-08 US disclosed
US-20010005758-A1 Process for the codimerization of polyunsaturated fatty substances and olefins by iron complexes INSTITUT FRANCAIS DE PETROLE (FR) 2001-06-28 US disclosed
US-4369325-A ANTIPHLOGISTIC AND DIURETIC ACTIVITY EGYT GYOGYSZERVEGYESZETI GYAR (HU) 1983-01-18 US disclosed
US-4284642-A DIURETICS, ANTIPHLOGISTICS EGYT GYOGYSZERVEGYESZETI GYAR (HU) 1981-08-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12544733-B2 Gas/liquid oligomerization reactor having successive zones with variable diameters NOD1, VAT1, DECR1 SIGMAR1 523/4885GRIN2D 1771/4885GRIN3B 3079/4885
US-12479780-B2 Oligomerisation process comprising a step of recycling a pre-cooled solvent COG4, PRPF40A, PRPF6 SIGMAR1 2077/4885GRIN2D 4680/4885GRIN3B 4636/4885
US-12157712-B2 Oligomerization process implementing the recycling of the gas headspace OXER1, OXGR1, RRS1 SIGMAR1 308/4885GRIN2D 4128/4885GRIN3B 4455/4885
US-12312288-B2 Gas/liquid oligomerization reactor comprising transverse internals DCXR, OTUB1, INF2 SIGMAR1 3917/4885GRIN2D 2868/4885GRIN3B 4291/4885
US-20020099243-A1 Process for the hydroformylation of olefinically unsaturated compounds in a non-aqueous ionic solvent NUDT1, PHOSPHO1, SRSF6 SIGMAR1 250/4885GRIN2D 4031/4885GRIN3B 3550/4885
US-20250084014-A1 OLIGOMERISATION PROCESS COMPRISING A STEP OF RECYCLING A PRE-COOLED SOLVENT COG4, PRPF40A, PRPF6 SIGMAR1 2077/4885GRIN2D 4680/4885GRIN3B 4636/4885
US-12364960-B2 Method for oligomerization in a reactor comprising a gas/liquid double distributor DUOX2, COASY, DUOX1 SIGMAR1 3068/4885GRIN2D 3941/4885GRIN3B 4308/4885
US-20030225303-A1 Hydroformylation process employing a cobalt-based catalyst in a non-aqueous liquid with improved catalyst recycling NUDT1, AP2S1, SRSF1 SIGMAR1 24/4885GRIN2D 553/4885GRIN3B 340/4885
US-12168213-B2 Ethylene oligomerization plant for producing alpha-olefins FDFT1, ECE1, OXER1 SIGMAR1 1332/4885GRIN2D 2644/4885GRIN3B 3534/4885
US-12151994-B2 Method for oligomerising olefins in an olifomerisation reactor C1S, C9, COG4 SIGMAR1 3268/4885GRIN2D 2293/4885GRIN3B 3360/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.